Results 31 to 40 of about 34,396 (232)
BMC Cancer, 2009 Background Hepcidin has an important role in iron metabolism. We investigated whether hepcidin was involved in renal cell carcinoma (RCC). Methods We measured serum hepcidin-25 levels in 32 patients by liquid chromatograpy (LC)-mass spectrometry (MS)/MS,
Abe Hideyuki +4 more
doaj +1 more source
Hepcidin expression in iron overload diseases is variably modulated by circulating factors. [PDF]
PLoS ONE, 2012 Hepcidin is a regulatory hormone that plays a major role in controlling body iron homeostasis. Circulating factors (holotransferrin, cytokines, erythroid regulators) might variably contribute to hepcidin modulation in different pathological conditions ...
Giulia Ravasi +11 more
doaj +1 more source
Lactoferrin. A natural glycoprotein involved in iron and inflammatory homeostasis [PDF]
, 2017 Human lactoferrin (hLf), an iron-binding multifunctional cationic glycoprotein secreted by exocrine glands and by neutrophils, is a key element of host defenses.
Cutone, Antimo +4 more
core +2 more sources
Hepcidin: inflammation versus hypoxia [PDF]
Sleep and Breathing, 2014 The finding of periodic leg movements (PLM) during polysomnographic recordings is a relatively common phenomenon. PLM is associated with a variety of sleep disorders [1, 2] and other diseases. An association between obstructive sleep apnea (OSA) and PLM [3–5] has been clearly established.
F, del Campo, C, Zamarrón
openaire +2 more sources
Hepcidin, an emerging and important player in brain iron homeostasis
Journal of Translational Medicine, 2018 Hepcidin is emerging as a new important factor in brain iron homeostasis. Studies suggest that there are two sources of hepcidin in the brain; one is local and the other comes from the circulation.
Driton Vela
doaj +1 more source
Hepcidin- A Burgeoning Biomarker [PDF]
National Journal of Laboratory Medicine, 2017 The discovery of hepcidin has triggered a virtual ignition of studies on iron metabolism and related disorders. The peptide hormone hepcidin is a key homeostatic regulator of iron metabolism.
Hemkant Manikrao Deshmukh +3 more
doaj +1 more source
Heme Oxygenase Induction Suppresses Hepatic Hepcidin and Rescues Ferroportin and Ferritin Expression in Obese Mice [PDF]
, 2017 Hepcidin, a phase II reactant secreted by hepatocytes, regulates cellular iron levels by increasing internalization of ferroportin-a transmembrane protein facilitating egress of cellular iron.
Arefiev, Yevgeniy +12 more
core +2 more sources
Hepcidin in hepatocellular carcinoma
British Journal of Cancer, 2022 AbstractHepatocellular carcinoma (HCC) is one of the most common reasons for cancer-related deaths. Excess iron increases HCC risk. Inevitably, hepcidin, the iron hormone that maintains systemic iron homoeostasis is involved in HCC pathology. Distinct from other cancers that show high hepcidin expression, HCC patients can show low hepcidin levels. Thus,
Jonathan H. Joachim, Kosha J. Mehta
openaire +5 more sources
Pediatrics and Neonatology, 2018 Background: Helicobacter pylori infection is associated with iron deficiency (ID) in children. Inflammatory cytokine reactions could influence the consequences of H. pylori infection.
Szu-Ta Chen +3 more
doaj +1 more source
Hepcidin and Host Defense against Infectious Diseases. [PDF]
, 2015 Hepcidin is the master regulator of iron homeostasis in vertebrates. The synthesis of hepcidin is induced by systemic iron levels and by inflammatory stimuli.
Ganz, Tomas +3 more
core +1 more source