Results 1 to 10 of about 2,189 (194)

Revolutionizing orthopedic healthcare: a systematic review unveiling recombinant antimicrobial peptides [PDF]

Frontiers in Microbiology
The increasing demand for orthopedic surgeries, including joint replacements, is driven by an aging population and improved diagnosis of joint conditions. Orthopedic surgeries carry a risk of infection, especially in patients with comorbidities. The rise
Vincenzo Pennone, Elena Rosini, Elena Mascheroni, Silvia Gianola, Greta Castellini, Silvia Bargeri, Arianna B. Lovati   +6 more
doaj   +6 more sources

The Era of Antimicrobial Peptides: Use of Hepcidins to Prevent or Treat Bacterial Infections and Iron Disorders [PDF]

Frontiers in Immunology, 2021
The current treatments applied in aquaculture to limit disease dissemination are mostly based on the use of antibiotics, either as prophylactic or therapeutic agents, with vaccines being available for a limited number of fish species and pathogens ...
Carolina Barroso, Carolina Barroso, Carolina Barroso, Pedro Carvalho, Magda Nunes, José F. M. Gonçalves, Pedro N. S. Rodrigues, Pedro N. S. Rodrigues, Pedro N. S. Rodrigues, João V. Neves, João V. Neves, João V. Neves   +11 more
doaj   +3 more sources

Verification of the Automated ELISA Assay for Hepcidin-25 in Human Serum [PDF]

Southeastern European Medical Journal, 2023
Introduction: Hepcidin-25, the bioactive form of hepcidin, is the master protein in regulating iron homeostasis. Serum concentrations, measured by different methods, are often incomparable and complicate results interpretation.
Tara Rolić, Sanja Mandić, Iva Lukić, Vesna Horvat, Ines Banjari   +4 more
doaj   +3 more sources

Human Antimicrobial Peptides and Proteins [PDF]

Pharmaceuticals, 2014
As the key components of innate immunity, human host defense antimicrobial peptides and proteins (AMPs) play a critical role in warding off invading microbial pathogens.
Guangshun Wang
doaj   +4 more sources

Molecular cloning and antibacterial activity of hepcidin from Chinese rare minnow (Gobiocypris rarus) [PDF]

Electronic Journal of Biotechnology, 2015
Background: Hepcidins, a kind of cysteine-rich antimicrobial peptides, play important roles in host immunological processes and iron regulation, which have been identified from several fish species.
Fei Ke, Yun Wang, Chuan-Shun Yang, Chen Xu   +3 more
doaj   +3 more sources

Identification of Antibacterial Activity of Hepcidin From Antarctic Notothenioid Fish [PDF]

Frontiers in Microbiology, 2022
Hepcidin is a small peptide composed of signal peptide, propeptide, and the bioactive mature peptide from N terminal to C terminal. Mature hepcidin is an antibacterial peptide and iron regulator with eight highly conserved cysteines forming four ...
Mingli Liu, Mingli Liu, Ruiqin Hu, Ruiqin Hu, Wenhao Li, Wenhao Li, Wenyi Yang, Wenyi Yang, Qianghua Xu, Qianghua Xu, Liangbiao Chen, Liangbiao Chen   +11 more
doaj   +2 more sources

The Antimicrobial Peptide LJ-hep2 from Lateolabrax japonicus Exerting Activities against Multiple Pathogenic Bacteria and Immune Protection In Vivo [PDF]

Marine Drugs, 2022
Hepcidin is widely present in many kinds of fish and is an important innate immune factor. A variety of HAMP2-type hepcidins have strong antimicrobial activity and immunomodulatory functions and are expected to be developed as substitutes for antibiotics.
Ruihao Gong, Zhe An, Weibin Zhang, Fangyi Chen, Ke-Jian Wang   +4 more
doaj   +2 more sources

Hepcidin-Dependent Regulation of Erythropoiesis during Anemia in a Teleost Fish, Dicentrarchus labrax. [PDF]

PLoS ONE, 2016
Anemia is a common disorder, characterized by abnormally low levels of red blood cells or hemoglobin. The mechanisms of anemia development and response have been thoroughly studied in mammals, but little is known in other vertebrates, particularly ...
João V Neves, Carolina Caldas, Miguel F Ramos, Pedro N S Rodrigues   +3 more
doaj   +5 more sources

Hepcidin as a risk marker for cardiovascular disease in periodontitis—A case control study

Journal of Indian Academy of Oral Medicine and Radiology, 2023
Background: Hepcidin is a 25 amino acid peptide expressed in the liver. Discovered as late as 2002, hepcidin is a master regulator of iron metabolism and is sensitive to inflammation. Chronic periodontitis, being an inflammatory condition, affects levels
Tejavathi Nagaraj, V S Vaishnavi, Holenarasipur Nagesh Santosh, Durga Okade, Pooja Sinha, J Anitha   +5 more
doaj   +1 more source

Molecular analysis of endocrine disruption in hornyhead turbot at wastewater outfalls in southern california using a second generation multi-species microarray. [PDF]

, 2013
Sentinel fish hornyhead turbot (Pleuronichthysverticalis) captured near wastewater outfalls are used for monitoring exposure to industrial and agricultural chemicals of ~ 20 million people living in coastal Southern California.
Angert, Mila, Baker, Michael E, Bay, Steven M, Carnevali, Oliana, Gully, Joseph R, Hardiman, Gary, Kelley, Kevin M, Lekmine, Narimene, Ludka, Colleen, Martella, Andrea, Ribecco, Cataldo, Ricciardelli, Eugenia, Schlenk, Daniel, Sprague, L James, Vidal-Dorsch, Doris E, Šášik, Roman   +15 more
core   +9 more sources