Results 1 to 10 of about 1,811 (95)

The comparison of acute phase proteins in experimentally induced canine acute pancreatitis [PDF]

open access: yesBMC Veterinary Research
Background Acute pancreatitis triggers the production of acute-phase proteins (APPs) in the body, among which C-reactive protein (CRP) is the most extensively studied and widely used for both diagnosis and prognosis. The diagnostic value of other APPs is
Eszter Tünde Kanyorszky   +6 more
doaj   +2 more sources

The Era of Antimicrobial Peptides: Use of Hepcidins to Prevent or Treat Bacterial Infections and Iron Disorders

open access: yesFrontiers in Immunology, 2021
The current treatments applied in aquaculture to limit disease dissemination are mostly based on the use of antibiotics, either as prophylactic or therapeutic agents, with vaccines being available for a limited number of fish species and pathogens ...
Carolina Barroso   +2 more
exaly   +3 more sources

Insights into the Antimicrobial Properties of Hepcidins: Advantages and Drawbacks as Potential Therapeutic Agents

open access: yesMolecules, 2015
The increasing frequency of multi-drug resistant microorganisms has driven research into alternative therapeutic strategies. In this respect, natural antimicrobial peptides (AMPs) hold much promise as candidates for the development of novel antibiotics ...
Lisa Lombardi   +2 more
exaly   +3 more sources

The Antimicrobial Peptide LJ-hep2 from Lateolabrax japonicus Exerting Activities against Multiple Pathogenic Bacteria and Immune Protection In Vivo [PDF]

open access: yesMarine Drugs, 2022
Hepcidin is widely present in many kinds of fish and is an important innate immune factor. A variety of HAMP2-type hepcidins have strong antimicrobial activity and immunomodulatory functions and are expected to be developed as substitutes for antibiotics.
Ruihao Gong   +4 more
doaj   +2 more sources

Identification of Antibacterial Activity of Hepcidin From Antarctic Notothenioid Fish [PDF]

open access: yesFrontiers in Microbiology, 2022
Hepcidin is a small peptide composed of signal peptide, propeptide, and the bioactive mature peptide from N terminal to C terminal. Mature hepcidin is an antibacterial peptide and iron regulator with eight highly conserved cysteines forming four ...
Mingli Liu   +11 more
doaj   +2 more sources

Revolutionizing orthopedic healthcare: a systematic review unveiling recombinant antimicrobial peptides [PDF]

open access: yesFrontiers in Microbiology
The increasing demand for orthopedic surgeries, including joint replacements, is driven by an aging population and improved diagnosis of joint conditions. Orthopedic surgeries carry a risk of infection, especially in patients with comorbidities. The rise
Vincenzo Pennone   +6 more
doaj   +2 more sources

Fish-derived hepcidins in cancer treatment: a scoping review

open access: yesBeni-Suef University Journal of Basic and Applied Sciences
Background The discovery of hepcidin, a peptide hormone primarily known for iron homeostasis regulation, has revealed promising anticancer properties.
Wan-Atirah Azemin   +2 more
exaly   +2 more sources

Human Antimicrobial Peptides as Therapeutics for Viral Infections

open access: yesViruses, 2019
Successful in vivo infection following pathogen entry requires the evasion and subversion of multiple immunological barriers. Antimicrobial peptides (AMPs) are one of the first immune pathways upregulated during infection by multiple pathogens, in ...
Aslaa Ahmed   +2 more
exaly   +3 more sources

Hepcidin as a risk marker for cardiovascular disease in periodontitis—A case control study

open access: yesJournal of Indian Academy of Oral Medicine and Radiology, 2023
Background: Hepcidin is a 25 amino acid peptide expressed in the liver. Discovered as late as 2002, hepcidin is a master regulator of iron metabolism and is sensitive to inflammation. Chronic periodontitis, being an inflammatory condition, affects levels
Tejavathi Nagaraj   +5 more
doaj   +1 more source

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