Results 51 to 60 of about 2,189 (194)
Phenotyping rare hepcidin deficiency [PDF]
Blood, 2018 In this issue of Blood , Sandhu et al 1 comprehensively catalog the individual data from all reported cases of hepcidin-deficient hemochromatosis related to HAMP , HJV , and TFR2 mutations to determine their phenotype compared with HFE hemochromatosis.
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Iron regulation by hepcidin [PDF]
Journal of Clinical Investigation, 2013 Hepcidin is a key hormone that is involved in the control of iron homeostasis in the body. Physiologically, hepcidin is controlled by iron stores, inflammation, hypoxia, and erythropoiesis. The regulation of hepcidin expression by iron is a complex process that requires the coordination of multiple proteins, including hemojuvelin, bone morphogenetic ...
Ningning, Zhao +2 more
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Fish-derived hepcidins in cancer treatment: a scoping review
Beni-Suef University Journal of Basic and Applied SciencesBackground The discovery of hepcidin, a peptide hormone primarily known for iron homeostasis regulation, has revealed promising anticancer properties.
Wan-Atirah Azemin +4 more
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FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
tudies of two kinds of hepcidins in the gonad of the mudskipper Boleophthalmus pectinirostris [PDF]
, 2015 大弹涂鱼（Boleophthalmuspectinirostris）分布于我国东南沿海潮间滩涂，生活于洞穴之中，因其肉质鲜美，营养丰富，是我国东南沿海的重要的养殖鱼类之一。前期的研究发现，生殖季节雄性大弹涂鱼在洞穴中建造产卵室，性成熟的雌雄鱼在产卵室内交配产卵，受精卵粘附在产卵室的顶部和四周，仔鱼需要5d才能孵出。虽然洞穴内底泥和海水含有许多致病菌，但大弹涂鱼受精卵在孵化期间卵膜和胚体始终保持清洁透明状态，孵化率达到99.7%。为了了解大弹涂鱼在生殖过程中的免疫抗菌机制 ...
李哲
core
Low pH enhances the action of maximin H5 against Staphylococcus aureus and helps mediate lysylated phosphatidylglycerol induced resistance [PDF]
, 2016 Maximin H5 (MH5) is an amphibian antimicrobial peptide specifically targeting Staphylococcus aureus. At pH 6, the peptide showed an increased ability to penetrate (∆П = 6.2 mN m-1) and lyse (lysis = 48 %) S.
Batabyal B. +22 more
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Annals of Gastroenterological Surgery, EarlyView.In hepatocellular carcinoma treated with atezolizumab–bevacizumab, responders showed RNA‐seq enrichment of immune and chemokine pathways with higher HAMP expression. In resected specimens, immunohistochemistry confirmed increased intratumoral CD8+ T‐cell density and hepcidin (HAMP), supporting HAMP plus CD8 as components of a composite predictor of ...
Shun Nakamura +9 more
wiley +1 more source
28-jähriger Patient mit erfolgreich behandelter dilatativer Kardiomyopathie [PDF]
, 2018 Zusammenfassung: Ein 28-jähriger Patient wurde mit dekompensierter Herzinsuffizienz notfallmäßig zugewiesen. In der Vorgeschichte bestand ein hypogonadotroper Hypogonadismus. Echokardiographisch fand sich eine dilatative Kardiomyopathie.
Burri, E. +4 more
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Clinical Journal of the American Society of Nephrology, 2009 Iron is the fourth most common element in the earth's crust and the most abundant transition metal in the human body. It is an essential element required for growth and survival. Maintaining the correct iron balance is crucial for health. All living organisms evolved sophisticated mechanisms to maintain appropriate iron levels in their cells and within
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Serum amyloid A is a positive acute phase protein in Russian sturgeon challenged with Aeromonas hydrophila [PDF]
, 2020 The immune system of sturgeons, one of the most ancient and economically valuable fsh worldwide, is poorly understood. The lack of molecular tools and data about infection biomarkers hinders the possibility to monitor sturgeon health during farming and ...
Aversa, Marcio +7 more
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