Results 91 to 100 of about 16,165 (220)

Prediction of hereditary nonpolyposis colorectal cancer using mRNA MSH2 quantitative and the correlation with nonmodifiable factor. [PDF]

World J Gastrointest Pathophysiol, 2021
Tedjasaputra TR, Hatta M, Massi MN, Natzir R, Bukhari A, Masadah R, Parewangi ML, Prihantono P, Nariswati R, Tedjasaputra V.   +9 more
europepmc   +1 more source

Cáncer hereditario: fundamentos genéticos [PDF]

, 2005
Genetic counseling plays a key role in the BRCA1/BRCA2 and hMLH1/hMSH2/hMSH6 testing process. The initial genetic counselling encounter will determine the appropriateness of the test by collecting a detailed family history and determining the likelihood ...
Caldés, Trinidad
core   +1 more source

Lynch Syndrome from a surgeon perspective: retrospective study of clinical impact of mismatch repair protein expression analysis in colorectal cancer patients less than 50 years old. [PDF]

, 2014
BACKGROUND: In clinical practice, unexpected diagnosis of colorectal cancer in young patients requires prompt surgery, thus genetic testing for Lynch Syndrome is frequently missed, and clinical management may result incorrect.
Baiocchi GL, Baronchelli C, Gheza F, Giulini SM., Marchina E, Portolani N, Scaglia A, Tiberio GA, Vermi W, Zogno C   +9 more
core   +1 more source

Hereditary Nonpolyposis Colorectal Cancer in Association with Crohn's Disease and Lynch Syndrome: The Importance of a Strict Endoscopic Surveillance. [PDF]

Case Rep Gastroenterol, 2022
Hahn GD, Wetwittayakhlang P, Afif W, Bessissow T, Lakatos PL.   +4 more
europepmc   +1 more source

A survey of the clinicopathological and molecular characteristics of patients with suspected Lynch syndrome in Latin America [PDF]

, 2017
Background: Genetic counselling and testing for Lynch syndrome (LS) have recently been introduced in several Latin America countries. We aimed to characterize the clinical, molecular and mismatch repair (MMR) variants spectrum of patients with suspected ...
A Giraldo, A Gomez, A Mendoza Sanchez, A Recalde, A Stella, A Umar, A Wagner, AD Clarizia, Adriana Della Valle, AL Moisio, Alexandra Martins, AM Wielandt, André Escremim de Paula, AR Cajal, BA Thompson, Benedito Mauro Rossi, BM Rossi, BM Rossi, C Castro-Mujica Mdel, C Castro-Mujica Mdel, C Houdayer, C Nique Carbajal, C Ortiz, C Sarroca, CA Vaccaro, CA Vaccaro, CA Vaccaro, Carlos Alberto Vaccaro, Carlos Sarroca, CG Rasuck, Claudia Barletta-Carrillo, CM Egoavil, Constantino Dominguez-Barrera, DD Buchanan, DE Germini, DV Viana, E Borras, Edenir Inêz Palmero, Eivind Hovig, Enrique Spirandelli, Erika Maria Monteiro-Santos, Evaluation of Genomic Applications in P, Prevention Working G, FC Silva da, Florencia Neffa, Florencia Spirandelli, Francisco López-Kostner, G Casey, G Chong, G Ponti, G Yeo, GH Garcia, H Hampel, H Kobayashi, H Song, Henrique de Campos Reis Galvão, HF Vasen, HF Vasen, Hélène Tubeuf, I Borelli, I Thiffault, IN Freitas de, J Norum, J Risco, JP Plazzer, JT Dunnen den, Julio Sanchez de Monte, K Alvarez, Karin Alvarez, L Perez-Cabornero, L. Lena Morillas, Luis Gustavo Capochin Romagnolo, M Aarnio, M Clendenning, M Cruz-Correa, M Dominguez-Valentin, M Nystrom-Lahti, M Pinheiro, M Pinheiro, M Rodriguez-Soler, M Roque, M Tanyi, MA Ramirez-Ramirez, MA RodriguezBigas, Maria del Carmen Castro-Mujica, MD Valentin, MD Valentin, Melva Gutiérrez Angulo, Mev Dominguez-Valentin, NJ Froggatt, Norma Teresa Rossi, O Soukarieh, P Ashton-Prolla, P Koehler-Santos, P Lastella, P Vahteristo, Pablo German Kalfayan, Patricia Ashton-Prolla, Patrik Wernhoff, Pål Møller, Richard Quispe, RP Kuiper, Rui Manuel Reis, S Gupta, Sabrina Daniela da Silva, Sergio Chialina, SMO Leite, Susana Revollo, Tamara Alejandra Piñero, V Alonso-Espinaco, W Sjursen, WE Jesus-Monge De, Ximena Taborga, Y Montenegro, Yenni Rodriguez   +113 more
core   +4 more sources

Functional Characterization of MutS Homologue Mismatch Repair Proteins and their Variants [PDF]

, 2012
Lynch syndrome (LS) is one of the most common hereditary cancer syndromes and may lead to cancer development, mainly in colon or in endometrium, for 20 years earlier than in general population. LS is an autosomal dominantly inherited disorder, associated
Kantelinen, Jukka Petteri
core  

Survival of hereditary non-polyposis colorectal cancer patients compared with sporadic colorectal cancer patients

Journal of Experimental & Clinical Cancer Research, 2008
Background Patients with hereditary non-poliposys colorectal cancer (HNPCC) have better prognosis than sporadic colorectal cancer (CRC). Aim of our retrospective study was to compare the overall survival between sporadic CRC and HNPCC patients.
Mete Lupe, Mottolese Marcella, Giannarelli Diana, Palmirotta Raffaele, Cosimelli Maurizio, Assisi Daniela, Stigliano Vittoria, Mancini Raffaello, Casale Vincenzo   +8 more
doaj   +1 more source

Molecular genetic approach for screening of hereditary non-polyposis colorectal cancer

Zdravniški Vestnik, 2005
Background: The main goal of knowledge concerning human diseases is to transfer as much as possible useful information into clinical applications.
Metka Ravnik-Glavač
doaj  

Investigating of microsatellites instability in patients with hereditary non-polyposis colorectal cancer in Isfahan

Advanced Biomedical Research, 2014
Background: Microsatellites or simple sequence repeats are repeating sequences of deoxyribonucleic acid (DNA). Mutation in mismatch repair (MMR) genes can cause microsatellites instability (MSI) in some tumors.
Vida Homayouni, Mansour Salehi, Mohammad Kazemi   +2 more
doaj   +1 more source

Deficient DNA mismatch repair and persistence of SARS-CoV-2 RNA shedding: a case report of hereditary nonpolyposis colorectal cancer with COVID-19 infection. [PDF]

BMC Infect Dis, 2021
Haque F, Lillie P, Haque F, Maraveyas A.
europepmc   +1 more source