Results 11 to 20 of about 16,258 (219)

Hereditary nonpolyposis colorectal cancer

Annals of Oncology, 1997
Colorectal cancer is a leading cause of cancer related death in both Europe and the United States. Approximately 20% of cases occur in familial aggregations making this disorder the most frequent form of hereditary neoplasia [1]. Consequently, patients with colorectal cancer often present with a positive family history which may have significant ...
S, O'Reilly, K A, Johnson, J D, Brensinger, F M, Giardiello   +3 more
openaire   +4 more sources

High Grade Dysplastic Rectal Adenoma in a Young Patient With Café-Au-Lait Spots: A Case Report. [PDF]

Clin Case Rep
ABSTRACT Colorectal cancer screening guidelines typically focus on familial history and age‐related risk factors, yet Café‐au‐lait macules could serve as early indicators for tailored surveillance protocols. This case underscores the importance of considering extracolonic manifestations in young patients presenting with colorectal symptoms.
Hamdan A, Zeid RA, Khalil J, Karam K, Fiani E.   +4 more
europepmc   +2 more sources

Extensive colectomy in colorectal cancer and hereditary nonpolyposis colorectal cancer – long-term results

Journal of Coloproctology, 2019
Background: Colorectal cancer survival is better in hereditary nonpolyposis colorectal cancer patients than in sporadic colorectal cancer patients and even for hereditary nonpolyposis colorectal cancer with colorectal cancer is not consensual that ...
Marisa D. Santos, Cláudio Silva, João Oliveira, Pedro Brandão, Mónica Sampaio, Ana Cristina Silva, Anabela Rocha, Eduarda Matos, Ricardo Marcos-Pinto   +8 more
doaj   +1 more source

Syndrome in question [PDF]

Anais Brasileiros de Dermatologia, 2015
Muir-Torre syndrome is a rare genodermatosis characterized by the occurrence of at least one sebaceous tumor associated with visceral neoplasia, but with no predisposing factors.
Catharina Maria Freire de Lucena Pousa, Fernanda Guedes Lavorato, Fernanda Valente Rehfeldt, Danielle Mann, Maria de Fátima Gonçalves Scotelaro Alves   +4 more
doaj   +1 more source

Hereditary Colorectal Cancer (CRC) Program in Latvia [PDF]

, 2003
Introduction The aim of the study is to evaluate the incidence and phenotype - genotype characteristics of hereditary colorectal cancer syndromes in Latvia in order to develop the basis of clinical management for patients and their relatives affected by ...
Arvids Irmejs, Andris Gardovskis, Viktors Borosenko, Marianna Bitina, Diana Aigare, Grzegorz Kurzawski, Janina Suchy, Bohdan Górski, Janis Gardovskis   +8 more
core   +2 more sources

Advanced Colon Cancer Before the Age of 20 Years: A Case for Extension of the Current Colonscopy Surveillance Guidelines in Hereditary Nonpolyposis Colorectal Cancer Syndrome

Canadian Journal of Gastroenterology, 2004
BACKGROUND: Hereditary nonpolyposis colorectal cancer (HNPCC) currently accounts for between 2% to 6% of all colorectal adenocarcinomas. Controversies exist regarding the current guidelines for colonoscopic screening for colon cancer.
Victor K Wong, Eric M Yoshida, Anthony G Ryan, Stephen GF Ho, Baljinder Salh   +4 more
doaj   +1 more source

Hereditary Colon Cancer

Canadian Journal of Gastroenterology, 1997
Hereditary colon cancer comprises approximately 10% of total colon cancer, a disease that affects 6% of the North American population.
Dawna M Gilchrist
doaj   +1 more source

Does sex of the patient play a role in survival for MSI colorectal cancer? [PDF]

, 2018
Microsatellite instability (MSI) is a feature of colorectal tumors that develops as a result of inactivation of the DNA mismatch repair system. It is found in about 15% of all colorectal cancers and is an important prognostic molecular marker when ...
Alecu, Lucian, Hainarosie, Razvan, Iaciu, Cristian I., Jecan, Radu C., Nitipir, Cornelia, Orlov, Cristina, Pantea Stoian, Anca, Pituru, Silviu, Slavu, Iulian, Stanculeanu, Dana L., Tulin, Adrian, Tulin, Raluca   +11 more
core   +3 more sources

Muir-Torre Syndrome: The Importance of a Detailed Family History

Case Reports in Ophthalmology, 2019
Muir-Torre syndrome, a variant of Lynch syndrome or hereditary nonpolyposis colorectal cancer, is an autosomal dominant disease characterized by skin neoplasms (sebaceous or keratoacanthomas) and visceral malignancies.
Christopher K.H. Burris, Maria E. Rodriguez, Meisha L. Raven, Devasis N. Reddy, Yaohui G. Xu, Janey L. Wiggs, Heather D. Potter, Daniel M. Albert   +7 more
doaj   +1 more source

A novel nonsense mutation of MSH2 gene in a Taiwanese family with hereditary nonpolyposis colorectal cancer

Kaohsiung Journal of Medical Sciences, 2011
Hereditary nonpolyposis colorectal cancer (HNPCC) is an autosomal dominant inherited disease predisposing to the development of colorectal cancers and several other malignancies (endometrium, ovaries, stomach, small bowel, hepatobiliary, and urinary ...
Wen-Chau Chen, Shao-Chieh Lin, Jenq-Chang Lee, 陳文超, 林劭潔, 李政昌   +5 more
doaj   +1 more source