Results 51 to 60 of about 16,258 (219)

Toward Timely Diagnosis of Pancreatic Cancer: Revolutionizing Early Detection Through Genomics, Artificial Intelligence, and Noninvasive Biomarkers

open access: yesJournal of Gastroenterology and Hepatology, Volume 41, Issue 3, Page 895-913, March 2026.
ABSTRACT Background Pancreatic ductal adenocarcinoma (PDAC) remains one of the most aggressive cancers, typically diagnosed at an advanced stage due to its subtle and often absent early symptoms. Despite representing only 3% of new cancer cases, it is projected to become the second leading cause of cancer‐related deaths by 2030.
Muhammad Masroor Hussain   +5 more
wiley   +1 more source

Ileocecal Adenocarcinoma and Ureteral Transitional Cell Carcinoma with Multiple Sebaceous Tumors and Keratoacanthomas in a Case of Muir-Torre Syndrome

open access: yesDermatology Research and Practice, 2010
Cutaneous neoplasms including sebaceous tumors, keratoacanthomas, and basal cell carcinomas with sebaceous differentiation can be markers of internal malignancy associated with the Muir-Torre Syndrome (MTS).
Michael C. Lynch, Bryan E. Anderson
doaj   +1 more source

Sebaceous gland tumors and internal malignancy in the context of Muir-Torre syndrome. A case report and review of the literature

open access: yesWorld Journal of Surgical Oncology, 2006
Background The Muir-Torre syndrome is a rare autosomal dominant condition and is currently considered a subtype of the more common hereditary nonpolyposis colorectal cancer syndrome, in which multiple primary malignancies occur together with sebaceous ...
Tsachalis T   +5 more
doaj   +1 more source

Do hereditary syndrome-related gynecologic cancers have any specific features? [PDF]

open access: yes, 2015
Hereditary syndromes are responsible for 10 % of gynaecologic cancers, among which hereditary breastovarian cancer and hereditary non-polyposis colon cancer syndromes, known as HBOC and Lynch syndromes respectively, present the highest relative risk.
Cunha, Teresa Margarida, Neto, Nelson
core   +1 more source

Patient‐Reported‐Outcome‐Measures (PROMs) After Gastrointestinal Endoscopic Resections

open access: yesUnited European Gastroenterology Journal, Volume 14, Issue 1, February 2026.
ABSTRACT Background Data on patient‐reported outcome measures (PROMs) of patients undergoing endoscopic resections have been sparse. The aim of our study was the prospective assessment of the Gastrointestinal Quality of Life Index (GIQLI) as a baseline and post‐endoscopic resection (ER) measurement in patients with epithelial mucosal neoplasms ...
Laura Retzbach   +4 more
wiley   +1 more source

Hereditary Nonpolyposis Colorectal Cancer (HNPCC)/Lynch Syndrome: Surveillance and Diagnostic strategies

open access: yesMajallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2021
Introduction: Hereditary nonpolyposis colorectal cancer (HNPCC, Lynch syndrome) is an autosomal dominant genetic disease. The disease is caused by a mutation in one of four genes of the DNA mismatch repair system and increases the risk for various ...
Mohammad Hassan Jokar   +2 more
doaj  

Rectal cancer in patients with hereditary nonpolyposis colorectal cancer: Surgical management and survival outcomes [PDF]

open access: yesHereditary Cancer in Clinical Practice, 2011
Nancy You Y   +5 more
doaj   +2 more sources

Urothelial carcinoma: Perioperative considerations from top to bottom

open access: yesCA: A Cancer Journal for Clinicians, Volume 75, Issue 6, Page 528-551, November/December 2025.
Abstract Urothelial carcinoma is an aggressive entity that is associated with significant morbidity, but there have been major advances in both our understanding of and treatment options for patients with this disease. In this review, the authors focus on novel therapeutic and diagnostic approaches in the perioperative setting, with an emphasis on ...
Wesley Yip   +8 more
wiley   +1 more source

GENETIC COUNSELOR UTILIZATION AND INTERPRETATION OF SOMATIC TUMOR TESTING IN EVALUATION FOR LYNCH SYNDROME [PDF]

open access: yes, 2019
Lynch syndrome (LS) is a hereditary cancer predisposition syndrome characterized by increased risk for colorectal and uterine cancers. Individuals with pathogenic variants in the mismatch repair (MMR) genes (MLH1, MSH2/EPCAM, MSH6, PMS2) are diagnosed ...
Williams, Danielle
core   +1 more source

Genetic testing for Lynch syndrome: family communication and motivation [PDF]

open access: yes, 2016
Current genetic counselling practice for Lynch syndrome (LS) relies on diagnosed index patients to inform their biological family about LS, referred to as the family-mediated approach.
Heijer, M. (Mariska) den   +5 more
core   +1 more source

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