Results 161 to 170 of about 102,928 (311)
Polymorphisms for extra heterochromatin in Phaulacridium marginale [PDF]
, 1973 Michael Westerman, P. G. Fontana
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Developmental Medicine &Child Neurology, EarlyView.Chromatin machinery influences how DNA is ‘wrapped’ around histones in the nucleosome of immune and brain cells. Plain language summary: https://onlinelibrary.wiley.com/doi/10.1111/dmcn.16299 Abstract We report eight children with de novo pathogenic DNA variants in chromatin‐related genes: MORC2, CHD7, KANSL1, KMT2D, ZMYND11, HIST1HIE, EP300, and KMT2B.
Russell C. Dale +14 more
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A bouquet-like attachment plate for telomeres in leptotene of rye revealed by heterochromatin staining [PDF]
, 1976 Julian B. Thomas, P. J. Kaltsikes
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Versatile roles of disordered transcription factor effector domains in transcriptional regulation
The FEBS Journal, EarlyView.Disordered effector domains (EDs) of transcription factors (TFs) play versatile roles in transcriptional regulation. These include mediating protein–protein interactions with protein complexes like, facilitating condensate formation to enhance transcriptional efficiency, modulating DNA‐binding specificity through genome scanning, and serving as hubs ...
Rhea R. Datta +3 more
wiley +1 more source
A MECHANISM OF CHROMOSOMAL REARRANGEMENTS: THE ROLE OF HETEROCHROMATIN AND ECTOPIC JOINING [PDF]
, 1978 Jong Sik Yoon, R. H. Richardson
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The FEBS Journal, EarlyView.Under normoxic conditions, the SUMOylated fraction of TFAP2A cannot interact with the Ku70/Ku80 complex, nor it can bind to chromatin. The unSUMOylated fraction pre‐occupies the chromatin of a subset of hypoxia‐induced genes together with the Ku70/Ku80 complex for basal euchromatin formation. Under hypoxic conditions, the SUMOylation equilibrium shifts
Amalia Kanoura +8 more
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Constitutive heterochromatin and karyotype variation in Indian pygmy mouse, Mus dunni [PDF]
, 1975 T. Sharma, Gaurav Garg
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Hybridization and gene expression: Beyond differentially expressed genes
Molecular Ecology, EarlyView.Abstract Gene expression has a key role in reproductive isolation, and studies of hybrid gene expression have identified mechanisms causing hybrid sterility. Here, we review the evidence for altered gene expression following hybridization and outline the mechanisms shown to contribute to altered gene expression in hybrids. Transgressive gene expression,
Anna Runemark +2 more
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THE CONSTRUCTION OF RING CHROMOSOMES OF AUTOSOMAL HETEROCHROMATIN IN DROSOPHILA MELANOGASTER [PDF]
, 1978 Arthur J. Hilliker
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Genetic Architecture of Immune Cell DNA Methylation in the Rhesus Macaque
Molecular Ecology, EarlyView.ABSTRACT Genetic variation that impacts gene regulation, rather than protein function, can have strong effects on trait variation both within and between species. Epigenetic mechanisms, such as DNA methylation, are often an important intermediate link between genotype and phenotype, yet genetic effects on DNA methylation remain understudied in natural ...
Christina E. Costa +12 more
wiley +1 more source