Results 31 to 40 of about 104,859 (295)
Heterochromatin is a condensed chromatin structure that represses transcription of repetitive DNA elements and developmental genes, and is required for genome stability.
Sarah MacKinnon+6 more
doaj +1 more source
FISH mapping and molecular organization of the major repetitive sequences of tomato [PDF]
This paper presents a bird's-eye view of the major repeats and chromatin types of tomato. Using fluorescence in-situ hybridization (FISH) with Cot-1, Cot-10 and Cot-100 DNA as probes we mapped repetitive sequences of different complexity on pachytene ...
Chang, S.B.+10 more
core +2 more sources
De Novo Polycomb Recruitment: Lessons from Latent Herpesviruses
The Human Herpesviruses persist in the form of a latent infection in specialized cell types. During latency, the herpesvirus genomes associate with cellular histone proteins and the viral lytic genes assemble into transcriptionally repressive ...
Sara A. Dochnal+2 more
doaj +1 more source
Liquid droplet formation by HP1α suggests a role for phase separation in heterochromatin. [PDF]
Gene silencing by heterochromatin is proposed to occur in part as a result of the ability of heterochromatin protein 1 (HP1) proteins to spread across large regions of the genome, compact the underlying chromatin and recruit diverse ligands.
Agard, David A+8 more
core +1 more source
Pericentromeric heterochromatin is hierarchically organized and spatially contacts H3K9me2 islands in euchromatin. [PDF]
Membraneless pericentromeric heterochromatin (PCH) domains play vital roles in chromosome dynamics and genome stability. However, our current understanding of 3D genome organization does not include PCH domains because of technical challenges associated ...
Acevedo, David+7 more
core +2 more sources
RNAi-mediated positive feedback loops are pivotal for the maintenance of heterochromatin, but how they are downregulated at heterochromatin-euchromatin borders is not well understood.
Jan H. Suhren+5 more
doaj +1 more source
Chromatin insulator elements: establishing barriers to set heterochromatin boundaries [PDF]
Epigenomic profiling has revealed that substantial portions of genomes in higher eukaryotes are organized into extensive domains of transcriptionally repressive chromatin.
Adam G West+9 more
core +1 more source
Mediator directs co-transcriptional heterochromatin assembly by RNA interference-dependent and -independent pathways. [PDF]
Heterochromatin at the pericentromeric repeats in fission yeast is assembled and spread by an RNAi-dependent mechanism, which is coupled with the transcription of non-coding RNA from the repeats by RNA polymerase II. In addition, Rrp6, a component of the
Eriko Oya+5 more
doaj +1 more source
H3K9 methylation (H3K9me) is a conserved marker of heterochromatin, a transcriptionally silent chromatin structure. Knowledge of the mechanisms for regulating heterochromatin distribution is limited.
Masato Sorida+12 more
doaj +1 more source
Sex Differences in Drosophila melanogaster Heterochromatin Are Regulated by Non-Sex Specific Factors. [PDF]
The eukaryotic genome is assembled into distinct types of chromatin. Gene-rich euchromatin has active chromatin marks, while heterochromatin is gene-poor and enriched for silencing marks.
Manasi S Apte, Victoria H Meller
doaj +1 more source