Results 31 to 40 of about 102,928 (311)
Heterochromatin: On the ADAR Radar? [PDF]
Current Biology, 2005 Vigilin proteins, the absence of which is known to cause abnormalities in heterochromatin, have been found to bind edited RNAs. Molecular complexes including vigilin comprise proteins involved with RNA editing and with DNA repair, making connections between these processes and RNA-based silencing mechanisms.
Weiwu Xie +3 more
openaire +2 more sources
Genome mapping and characterization of the
BMC Genomics, 2010 Background Heterochromatin plays an important role in chromosome function and gene regulation. Despite the availability of polytene chromosomes and genome sequence, the heterochromatin of the major malaria vector Anopheles gambiae has not been mapped and
Sharakhova Maria V +6 more
doaj +1 more source
PLoS Genetics, 2023 Heterochromatin is a condensed chromatin structure that represses transcription of repetitive DNA elements and developmental genes, and is required for genome stability.
Sarah MacKinnon +6 more
doaj +1 more source
Positional changes of pericentromeric heterochromatin and nucleoli in postmitotic Purkinje cells during murine cerebellum development [PDF]
, 2004 Previous studies revealed changes of pericentromeric heterochromatin arrangements in postmitotic Purkinje cells (PCs) during postnatal development in the mouse cerebellum (Manuelidis, 1985; Martou and De Boni, 2000). Here, we performed vibratome sections
Cremer, Thomas +4 more
core +1 more source
FISH mapping and molecular organization of the major repetitive sequences of tomato [PDF]
, 2008 This paper presents a bird's-eye view of the major repeats and chromatin types of tomato. Using fluorescence in-situ hybridization (FISH) with Cot-1, Cot-10 and Cot-100 DNA as probes we mapped repetitive sequences of different complexity on pachytene ...
Chang, S.B. +10 more
core +2 more sources
De Novo Polycomb Recruitment: Lessons from Latent Herpesviruses
Viruses, 2021 The Human Herpesviruses persist in the form of a latent infection in specialized cell types. During latency, the herpesvirus genomes associate with cellular histone proteins and the viral lytic genes assemble into transcriptionally repressive ...
Sara A. Dochnal +2 more
doaj +1 more source
Liquid droplet formation by HP1α suggests a role for phase separation in heterochromatin. [PDF]
, 2017 Gene silencing by heterochromatin is proposed to occur in part as a result of the ability of heterochromatin protein 1 (HP1) proteins to spread across large regions of the genome, compact the underlying chromatin and recruit diverse ligands.
Agard, David A +8 more
core +1 more source
Cell Reports, 2017 RNAi-mediated positive feedback loops are pivotal for the maintenance of heterochromatin, but how they are downregulated at heterochromatin-euchromatin borders is not well understood.
Jan H. Suhren +5 more
doaj +1 more source
Chromatin insulator elements: establishing barriers to set heterochromatin boundaries [PDF]
, 2012 Epigenomic profiling has revealed that substantial portions of genomes in higher eukaryotes are organized into extensive domains of transcriptionally repressive chromatin.
Adam G West +9 more
core +1 more source
Mediator directs co-transcriptional heterochromatin assembly by RNA interference-dependent and -independent pathways. [PDF]
PLoS Genetics, 2013 Heterochromatin at the pericentromeric repeats in fission yeast is assembled and spread by an RNAi-dependent mechanism, which is coupled with the transcription of non-coding RNA from the repeats by RNA polymerase II. In addition, Rrp6, a component of the
Eriko Oya +5 more
doaj +1 more source