Epigenetics and triplet-repeat neurological diseases [PDF]
The term ‘junk DNA’ has been reconsidered following the delineation of the functional significance of repetitive DNA regions. Typically associated with centromeres and telomeres, DNA repeats are found in nearly all organisms throughout their genomes ...
Festenstein, RJ, Nageshwaran, S
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Heterochromatin is usually thought of as a stable and inactive region of the genome.
openaire +5 more sources
Oogenesis: Active Heterochromatin [PDF]
The genome of Drosophila is protected from DNA damage during oogenesis by a mechanism involving short RNAs. Surprisingly transcription of these RNAs requires that their DNA is associated with a histone modification usually associated with gene silencing.
openaire +3 more sources
The composition and organization of Drosophila heterochromatin are heterogeneous and dynamic
Heterochromatin is enriched for specific epigenetic factors including Heterochromatin Protein 1a (HP1a), and is essential for many organismal functions.
Joel M Swenson+4 more
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The cAMP signaling pathway regulates Epe1 protein levels and heterochromatin assembly.
The epigenetic landscape of a cell frequently changes in response to fluctuations in nutrient levels, but the mechanistic link is not well understood.
Kehan Bao+11 more
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The significance of cytogenetics for the study of karyotype evolution and taxonomy of water bugs (Heteroptera, Belostomatidae) native to Argentina [PDF]
Male meiosis behaviour and heterochromatin characterization of three big water bug species were studied. Belostoma dentatum (Mayr, 1863), B. elongatum Montandon, 1908 and B. gestroi Montandon, 1903 possess 2n = 26 + X1X2Y (male).
Bressa, Maria Jose+2 more
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C-banding, fluorescent staining and NOR location in holokinetic chromosomes of bugs of the Neotropical genus Antiteuchus (Heteroptera: Pentatomidae: Discocephalinae) [PDF]
Different cytogenetic techniques including C-banding, base-specific fluorochromes and silver nitrate staining were used to compare the karyotypes of three species of bugs, representatives of the Neotropical genus Antiteuchus, namely A.
de Souza, Maria José, Lanzone, Cecilia
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Heterochromatin as an Important Driver of Genome Organization
Heterochromatin is a constituent of eukaryotic genomes with functions spanning from gene expression silencing to constraining DNA replication and repair.
Andrés Penagos-Puig+1 more
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Transcription of satellite DNAs in insects [PDF]
Chromatin condensation is an important regulatory mechanism of gene silencing as well as gene activation for the hundreds of functional protein genes harbored in heterochromatic regions of different insect species.
D. Ugarkovic+3 more
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Imaging the Response to DNA Damage in Heterochromatin Domains
The eukaryotic genome is assembled in a nucleoprotein complex called chromatin, whose organization markedly influences the repair of DNA lesions. For instance, compact chromatin states, broadly categorized as heterochromatin, present a challenging ...
Audrey Chansard+3 more
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