Results 71 to 80 of about 133,661 (356)

FISH-aimed karyotype analysis in Aconitum subgen : aconitum reveals excessive rDNA sites in tetraploid taxa [PDF]

, 2018
The location of 5S and 35S rDNA sequences in chromosomes of four Aconitum subsp. Aconitum species was analyzed after fluorescence in situ hybridization (FISH). Both in diploids (2n = 2x = 16; Aconitum variegatum, A. degenii) and tetraploids (2n = 4× = 32;
Grabowska-Joachimiak, Aleksandra, Hasterok, Robert, Joachimiak, Andrzej, Musiał, Krystyna, Sliwinska, Elwira   +4 more
core   +2 more sources

Ring-like distribution of constitutive heterochromatin in bovine senescent cells. [PDF]

PLoS ONE, 2011
BACKGROUND: Cells that reach "Hayflick limit" of proliferation, known as senescent cells, possess a particular type of nuclear architecture. Human senescent cells are characterized by the presence of highly condensed senescent associated heterochromatin ...
Andrey Pichugin, Nathalie Beaujean, Xavier Vignon, Yegor Vassetzky   +3 more
doaj   +1 more source

Patterns of Heterochromatin Transitions Linked to Changes in the Expression of Plasmodium falciparum Clonally Variant Genes

Microbiology Spectrum, 2023
The survival of malaria parasites in the changing human blood environment largely depends on their ability to alter gene expression by epigenetic mechanisms.
Lucas Michel-Todó, Cristina Bancells, Núria Casas-Vila, Núria Rovira-Graells, Carles Hernández-Ferrer, Juan R. González, Alfred Cortés   +6 more
doaj   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

ZKSCAN3 counteracts cellular senescence by stabilizing heterochromatin

Nucleic Acids Research, 2020
Zinc finger protein with KRAB and SCAN domains 3 (ZKSCAN3) has long been known as a master transcriptional repressor of autophagy. Here, we identify a novel role for ZKSCAN3 in alleviating senescence that is independent of its autophagy-related activity.
Huifang Hu, Qianzhao Ji, Moshi Song, Jie Ren, Zunpeng Liu, Zehua Wang, Xiaoqian Liu, K. Yan, Jianli Hu, Yaobin Jing, Si Wang, Weiqi Zhang, Guang-Hui Liu, J. Qu   +13 more
semanticscholar   +1 more source

Cytological features of penaut genome [PDF]

, 2017
The genus Arachis is composed of 82 species (Krapovickas and Gregory 1994; Valls and Simpson 2005; Valls et al 2013; Santana and Valls 2015) mainly distributed within a large region of South America, which extends from the eastern foothills of the Andes ...
Chalup, Laura María Isabel, Lavia, Graciela Inés, Ortiz, Alejandra Marcela, Robledo Dobladez, Germán Ariel, Samoluk, Sergio Sebastián, Seijo, José Guillermo, Silvestri, María Celeste   +6 more
core   +1 more source

A Modular and Customizable CRISPR/Cas Toolkit for Epigenome Editing of Cis‐regulatory Modules

Advanced Science, EarlyView.
Epigenome editing surpasses genome editing in gene regulation. Modular epigenome editing frameworks are developed to interrogate cis‐regulome, enabling tunable reprogramming of cis‐elements, uncovering their epigenetic responsiveness and cross‐species portability.
Lingrui Zhang, Jianxin Fu, Tiandan Long, Chao Zhang, Fuhua Fan, Zhaobo Lang, Jian‐Kang Zhu   +6 more
wiley   +1 more source

Heterochromatin anomalies and double-stranded RNA accumulation underlie C9orf72 poly(PR) toxicity

Science, 2019
How dipeptide repeats cause pathology A repeat expansion in the chromosome 9 open reading frame 72 (C9orf72) gene is the most common known cause of two neurodegenerative diseases: frontotemporal dementia and amyotrophic lateral sclerosis.
Yong-Jie Zhang, Lin Guo, Patrick K Gonzales, Tania F. Gendron, Yanwei Wu, Karen R. Jansen-West, Aliesha D O'Raw, Sarah R Pickles, M. Prudencio, Y. Carlomagno, Mariam A. Gachechiladze, Connor H. Ludwig, Ruilin Tian, Jeannie Chew, M. DeTure, Wen‐lang Lin, Jimei Tong, Lillian M. Daughrity, Mei Yue, Yuping Song, Jonathan W Andersen, M. Castanedes-Casey, Aishe Kurti, A. Datta, G. Antognetti, A. McCampbell, R. Rademakers, Björn E. Oskarsson, D. Dickson, M. Kampmann, Michael E. Ward, J. Fryer, C. Link, J. Shorter, L. Petrucelli   +34 more
semanticscholar   +1 more source

Investigation of marmoset hybrids (Cebuella pygmaea x Callithrix jacchus) and related Callitrichinae (Platyrrhini) by cross-species chromosome painting and comparative genomic hybridization [PDF]

, 2005
We report on the cytogenetics of twin offspring from an interspecies cross in marmosets (Callitrichinae, Platyrrhini), resulting from a pairing between a female Common marmoset (Callithrix jacchus, 2n = 46) and a male Pygmy marmoset (Cebuella pygmaea, 2n
Canavez FC, Dugoujon JM, G. Anzenberger, M. Münch, M. Neusser, Moore CM, Muller S, Muller S, Natori M, Pellicciari C, Ratomponirina C, Rosenberger AL, Rumpler Y, Rylands AB, S. Müller, Yunis E   +15 more
core   +1 more source

Super‐Resolution Compatible DNA Labeling Technique Reveals Chromatin Mobility and Organization Changes During Differentiation

Advanced Science, EarlyView.
A novel chromatin‐labeling probe is developed to investigate chromatin mobility during differentiation. The silicon rhodamine–conjugated dCTP is efficiently delivered into iPSCs and NSCs using a synthetic transporter. Super‐resolution microscopy and single‐particle tracking show decreased chromatin mobility during differentiation.
Maruthi K. Pabba, Miroslav Kuba, Tomáš Kraus, Kerem Celikay, Janis Meyer, Sunil Kumar Pradhan, Andreas Maiser, Hartmann Harz, Heinrich Leonhardt, Karl Rohr, Michal Hocek, M. Cristina Cardoso   +11 more
wiley   +1 more source