Results 81 to 90 of about 133,661 (356)
Heterochromatin: an epigenetic point of view in aging
Experimental and Molecular Medicine, 2020 Aging is an inevitable process of life. Defined by progressive physiological and functional loss of tissues and organs, aging increases the risk of mortality for the organism.
Jong-Hyuk Lee +3 more
semanticscholar +1 more source
Distribution of chromosome 18 and X centric heterochromatin in the interphase nucleus of cultured human cells [PDF]
, 1990 In situ hybridization of human chromosome 18 and X-specific alphoid DNA-probes was performed in combination with three dimensional (3D) and two dimensional (2D) image analysis to study the interphase distribution of the centric heterochromatin (18c and ...
Agard +63 more
core +1 more source
Advanced Science, EarlyView.This study presents telomere‐to‐telomere genome assemblies for two populations of Larimichthys crocea. We identified centromere‐specific tandem repeats invaded by LTR/ERV1 retrotransposons, unique 5S rRNA enrichment patterns, and population‐specific structural variants. Comparative genomic analyses further reveal distinct adaptive mechanisms in the MYD
Yu Cui +9 more
wiley +1 more source
Quantitative analysis of chromatin compaction in living cells using FLIM-FRET [PDF]
, 2009 FRET analysis of cell lines expressing fluorescently tagged histones on separate nucleosomes demonstrates that variations in chromosome compaction occur during ...
Angus I. Lamond +52 more
core +5 more sources
Advanced Science, EarlyView.The quantitative proteomic and phosphoproteomic profiling reveals dynamic phosphorylation regulation of sperm morphogenesis. Kinase‐substrate phosphorylation network and phosphorylation module analysis, followed by in vivo knockdown and knockout analysis, identify TTBK2 and CSNK1G1 as key regulators of morphogenesis, including head, flagellar, and ...
Tianyu Zhu +25 more
wiley +1 more source
Ribosomal DNA heterochromatin in plants [PDF]
Cytogenetic and Genome Research, 2005 The aim of this review is to integrate earlier results and recent findings to present the current state-of-the-art vision concerning the dynamic behavior of the ribosomal DNA (rDNA) fraction in plants. The global organization and behavioral features of rDNA make it a most useful system to analyse the relationship between chromatin topology and gene ...
Neves, N. +5 more
openaire +4 more sources
H3K9me3-heterochromatin loss at protein-coding genes enables developmental lineage specification
Science, 2019 Reversing chromatin dynamics for development Compacted chromatin regions, marked by trimethylation of histone H3 at position lysine 9 (H3K9me3), occur at highly repeated DNA sequences, helping to suppress recombination and gene expression.
Dario Nicetto +14 more
semanticscholar +1 more source
Nature Communications, 2020 In flowering plants, heterochromatin is demarcated by the histone variant H2A.W, elevated levels of the linker histone H1, and specific epigenetic modifications, such as high levels of DNA methylation at both CG and non-CG sites.
Pierre Bourguet +10 more
semanticscholar +1 more source
Biphasic euchromatin-to-heterochromatin transition on the KSHV genome following de novo infection. [PDF]
, 2013 The establishment of latency is an essential step for the life-long persistent infection and pathogenesis of Kaposi's sarcoma-associated herpesvirus (KSHV).
Brulois, Kevin +6 more
core +3 more sources
Sonoepigenetic Modification Mechanoprimes Early Osteogenic Commitment in Mesenchymal Stem Cells
Advanced Science, EarlyView.Brief 10 min bursts of high frequency (10 MHz) vibrational mechanostimulation to stem cells are shown to activate their epigenetic machinery to condition their differentiation down an osteogenic lineage within just 3 days, which is much earlier than that with other forms of mechanostimuli, and without requiring any biochemical additives. Abstract Cells
Lizebona A. Ambattu +3 more
wiley +1 more source