Results 161 to 170 of about 169,803 (413)
Advanced Science, EarlyView.The authors introduce a high‐throughput synthesis using amide‐sulfoxonium ylides as new nucleophilic reagents, enabling a catalyst‐ and base‐free hydrocarbonation of terminal alkynes under mild conditions, resulting in various E‐alkene substituted (hetero)amide‐sulfoxonium ylides with excellent regio‐ and stereoselectivity. The late‐stage modifications
Haiting Wu +6 more
wiley +1 more source
Synthesis of (macro)heterocycles by consecutive/repetitive isocyanide-based multicomponent reactions
Beilstein Journal of Organic Chemistry, 2019 Isocyanide-based multicomponent reactions are a versatile tool in the synthesis of heterocycles. This review describes recently developed approaches based on the combination of consecutive or repetitive isocyanide-based multicomponent reactions for the ...
Angélica de Fátima S. Barreto +1 more
doaj +1 more source
Synthesis and reduction of 10-phthalimidocamphor oxime
Acta Chimica Slovenica, 2017 10-Phthalimidocamphor oxime was prepared from easily available 10-iodocamphor in two steps. Reduction of the oxime functionality resulted in the formation of two novel polycyclic isoindolinone heterocycles, the attempted preparation of the primary amine ...
Uroš Grošelj +3 more
doaj +1 more source
On the Base Strength of Some Nitrogen Heterocycles in the Excited State [PDF]
, 1956 Noboru Mataga, Y. Kaifu, Masao Koizumi
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Advanced Science, EarlyView.Pd(II)/Cu(I) co‐catalyzed dual Csp2─Csp3 bonds construction from unactivated alkenes and arylsulfonyl chlorides to access benzo‐fused heterocycles with high efficiency and chemoselectivity. Abstract Transition‐metal‐catalyzed transformations offer a powerful approach to rapidly synthesize complex benzo‐fused heterocycles, crucial for drug and material ...
Jiahui Huang +9 more
wiley +1 more source
The tert-Amino Effect in Heterocyclic Chemistry. Synthesis of Spiro Heterocycles
Molecules, 2005 The tert-amino reaction effect was examined. A new method to synthesize spiro heterocycles is presented. It was shown that the “tert-amino effect†could be applied to the formation of spiro-fused heterocycles.
Y. Morzherin +4 more
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Radical‐Polar Crossover Bicyclization Enables a Modular Synthesis of Saturated Bicyclic Amines
Advanced Science, EarlyView.Herein, we report the successful realization of a radical‐polar crossover bicyclization reaction from easily available cyclopropylamines and substituted alkenes through photoredox catalysis. This approach introduces an innovative methodology for the de novo synthesis of a diverse collection of 4/5‐, 5/5‐, 6/5‐,7/5‐ and 5/6‐fused saturated bicyclic ...
Dewei Feng +4 more
wiley +1 more source
An Overview of Saturated Cyclic Ethers: Biological Profiles and Synthetic Strategies
Molecules, 2019 Saturated oxygen heterocycles are widely found in a broad array of natural products and other biologically active molecules. In medicinal chemistry, small and medium rings are also important synthetic intermediates since they can undergo ring-opening and
Qili Lu +3 more
doaj +1 more source
Ligand-Promoted Meta-C-H Arylation of Anilines, Phenols, and Heterocycles.
Journal of the American Chemical Society, 2016 Here we report the development of a versatile 3-acetylamino-2-hydroxypyridine class of ligands that promote meta-C-H arylation of anilines, heterocyclic aromatic amines, phenols, and 2-benzyl heterocycles using norbornene as a transient mediator.
Peng Wang +9 more
semanticscholar +1 more source
Advanced Science, EarlyView.Dual biomimetic active sites, i.e., mononuclear {ZnII(L)(H2O)} and dinuclear {L2ZnII(CHO2)(OH)ZnIIL2}, have been successfully intergrated into a metal–organic cage, Zn20‐MOC. These two different active sites in Zn20‐MOC catalyze different steps of cascade trimerization of 1,2‐diaminocyclohexane. The mononuclear {ZnII(L)(H2O)} site catalyzes the initial
Xiao‐Jun Chai +10 more
wiley +1 more source