Results 161 to 170 of about 128,452 (331)

Nonheme Fe Enzyme‐Catalyzed Enantiodivergent Nitrogen Migration: Directed Evolution and Computational Study of Isopenicillin N Synthases for Biocatalytic Synthesis of Arylglycines

Angewandte Chemie, EarlyView.
Nonheme Fe enzyme isopenicillin N synthase was reprogrammed and evolved as an efficient nitrogen migratase IPNSNim, converting diverse azanyl esters to valuable l‐arylglycines with up to 16 000 TTN and 97:3 e.r. IPNSNim and ACCONim allowed enantiodivergent preparation of both l‐ and d‐arylglycines.
Ken Lin, Liu‐Peng Zhao, Shengchun Wang, Huichong Liu, Yu Zhang, Binh Khanh Mai, Peng Liu, Yang Yang   +7 more
wiley   +2 more sources

Synthesis of Nitrogen Heterocycles Utilizing Molecular Nitrogen as a Nitrogen Source and Attempt to Use Air Instead of Nitrogen Gas

, 2009
Miwako Mori
openalex   +1 more source

Double E─H Bond Activation of Ammonia and Water by Cyclic Gallaphosphene L(OCP)GaPGaL

Angewandte Chemie, EarlyView.
Cyclic gallaphosphene 1 undergoes a twofold E─H bond activation with ammonia and water via a beneficial interplay between the polar “GaPGa” unit and the electrophilic nature of the C center in the bridging PCO unit, yielding six‐membered heterocycles 2 and 3, in which both nucleophilic phosphorus atoms are protonated.
Mahendra K. Sharma, Christoph Wölper, Gebhard Haberhauer, Stephan Schulz   +3 more
wiley   +2 more sources

Synthesen von Heterocyclen, CCVII Mesoionische Pyrimidine und Thiazine / Syntheses of Heterocycles, CCVII Mesoionic Pyrimidines and Thiazines [PDF]

, 1977
Erich Ziegler, W. Steiger, Charilaos Strangas   +2 more
openalex   +1 more source

Predictive, Data‐Driven Design of Red‐Light Photoredox Catalysts for C─Heteroatom Bond Formation

Angewandte Chemie, EarlyView.
From redox numbers to red light: Donor oxidation and core reduction potentials predict E0‐0 in cyanoarene dyes, guiding selection of an efficient red‐light catalyst, 4MeODPATPN (PC13). Under 620 nm light, PC13 facilitates Ni‐catalyzed C─heteroatom cross‐couplings (C─N, C─O, C─S) with high functional‐group tolerance and reduced hydrodehalogenation ...
Amir Gizatullin, Tingting Yuan, Sascha Grotjahn, Luigi Cavallo, Burkhard König, Chen Zhu, Magnus Rueping   +6 more
wiley   +2 more sources

Polar Heterobenzylic C(sp³)–H Chlorination Pathway Enabling Efficient Diversification of Aromatic Nitrogen Heterocycles [PDF]

, 2023
Soham Maity, Marco A. Lopez, Desiree M. Bates, Shishi Lin, Shane W. Krska, Shannon S. Stahl   +5 more
openalex   +1 more source

Photothermal Conversion Promotes Challenging SNAr for Facile C─N Bond Formation

Angewandte Chemie, EarlyView.
Photothermal conversion enables facile aromatic C─N bond formation via red light irradiation. A variety of inter‐ and intramolecular SNAr transformations are achieved under mild, schematically simple conditions. Additionally, a thermally promoted halogen exchange mechanism provides access to aryl bromides, chlorides, and fluorides – making this ...
Megan E. Matter, Rory C. Devin, Erin E. Stache   +2 more
wiley   +1 more source

Heterocycle-based MMP Inhibitors with P2′ Substituents

, 2001
Stanisław Pikul, Kelly McDow Dunham, Neil G. Almstead, Biswanath De, Michael G. Natchus, Yetunde O. Taiwo, Lisa E. Williams, Barbara A. Hynd, Lily C. Hsieh, Michael J. Janusz, Fei Gu, Glen E. Mieling   +11 more
openalex   +1 more source

Cationic Cascade Strategy for the Synthesis of Dihydrobenzofuran and Isochromane Scaffolds. [PDF]

Org Lett
Zybura PK, Grant KJ, Frontier AJ.
europepmc   +1 more source

Enantioselective rapid assembly of bis-heterocycles by sequential palladium-catalyzed aza-Heck cyclization coupling reaction. [PDF]

Sci Adv
Wang L, Wu S, Zhang W, Zhang S, Dong J, Hu W, Zhou C, Gao L, Zhou L, Zhang J.   +9 more
europepmc   +1 more source