Results 51 to 60 of about 9,440 (222)

Sorting mRNA Molecules for Cytoplasmic Transport and Localization

Frontiers in Genetics, 2018
In eukaryotic cells, gene expression is highly regulated at many layers. Nascent RNA molecules are assembled into ribonucleoprotein complexes that are then released into the nucleoplasmic milieu and transferred to the nuclear pore complex for nuclear ...
Nathalie Neriec, Piergiorgio Percipalle, Piergiorgio Percipalle   +2 more
doaj   +1 more source

Differential expression of heterogenous nuclear ribonucleoproteins in viral co-infections. [PDF]

, 2020
Co-infection is a phenomena by which a host or cell is infected by at least two pathogens (1, 2). The severe acute respiratory syndrome coronavirus 2, SARS-CoV-2, has resulted in the death of greater than 200,000 people in the United States in less than
Shahan Mamoor
core   +1 more source

A model for heterogeneous nuclear ribonucleoproteins in telomere and telomerase regulation [PDF]

Oncogene, 2002
The heterogeneous nuclear ribonucleoproteins (hnRNPs) are a large family of nucleic acid binding proteins that are often found in, but not restricted to, the 40S-ribonucleoprotein particle. Subsets of hnRNPs are strictly nuclear while others shuttle between the nucleus and cytoplasm.
Lance P, Ford, Woodring E, Wright, Jerry W, Shay   +2 more
openaire   +2 more sources

Long Non-Coding RNAs and the Innate Immune Response

Non-Coding RNA, 2019
Innate immunity provides the initial defence against infection and it is now clear that long non-coding RNAs (lncRNAs) are important regulators of this response.
Marina R. Hadjicharalambous, Mark A. Lindsay   +1 more
doaj   +1 more source

Vitamin B12 Reduces TDP-43 Toxicity by Alleviating Oxidative Stress and Mitochondrial Dysfunction

Antioxidants, 2021
TAR DNA-binding protein 43 (TDP-43) is a member of an evolutionarily conserved family of heterogeneous nuclear ribonucleoproteins that modulate multiple steps in RNA metabolic processes.
Yu-Mi Jeon, Younghwi Kwon, Shinrye Lee, Seyeon Kim, Myungjin Jo, Seongsoo Lee, Sang Ryong Kim, Kiyoung Kim, Hyung-Jun Kim   +8 more
doaj   +1 more source

Heterogeneous Nuclear Ribonucleoprotein H1, a Novel Nuclear Autoantigen [PDF]

Clinical Chemistry, 2009
AbstractBackground: Serum samples from patients with autoimmune connective tissue diseases that show a finely speckled antinuclear antibody (ANA) on indirect immune-fluorescence often have antibodies against unknown nuclear target antigens. To search for such autoantigens we applied a proteomic approach using sera from patients with a high ANA titer ...
Bergh, Karien, Hooijkaas, H (Herbert), Blockmans, D, Westhovens, R, De Beeck, KO, Verschueren, P, Goorbergh, Diana, Merwe, Joop, Fijak, M, Klug, J, Michiels, G, Devogelaere, B, De Smedt, H, Derua, R, Waelkens, E, Blanckaert, N, Bossuyt, X   +16 more
openaire   +3 more sources

Heterogeneous Nuclear Ribonucleoproteins: Implications in Neurological Diseases [PDF]

, 2020
Heterogenous nuclear ribonucleoproteins (hnRNPs) are a complex and functionally diverse family of RNA binding proteins with multifarious roles. They are involved, directly or indirectly, in alternative splicing, transcriptional and translational ...
Asi, Y, Low, Y-H, Foti, SC, Lashley, T
core  

Heterogeneous nuclear ribonucleoproteins as targets of autoantibodies in systemic rheumatic diseases. [PDF]

, 2011
peer reviewedBACKGROUND: Heterogeneous nuclear ribonucleoproteins (hnRNP) are abundant nucleoplasmic pre-mRNA-binding proteins. The aim of this study was to unravel the mosaic of autoantibodies to hnRNP's in systemic rheumatic diseases.
Waelkens, E, Van Steen, Kristel, Rita Derua, De Vlam, K, Patrick Verschueren, Van den Bergh, Karolien, Bergh, Karien, René Westhovens, Derua, R, Daniel Blockmans, Blockmans, D, De Vlam, Kurth, Karolien Van den Bergh, Bossuyt, X, Xavier Bossuyt, Bossuyt, Xavier, Kurt De Vlam, Westhovens, R, Van Steen, KristelGE348010008564850000-0001-6158-4538FB3086B8-F0ED-11E1-A9DE-61C894A0A6B4, Op de Beeck, K, Blockmans, Daniel, Herbert Hooijkaas, Op De Beeck, Katrijn, Derua, Rita, Vermeersch, Pieter, Van den Bergh, K, Maes, Liesbeth, Van Steen, K, Hooijkaas, Herbert, Waelkens, Etienne, Verschueren, Patrick, Katrijn Op De Beéck, Kristel Van Steen, Verschueren, P, Pieter Vermeersch, Etienne Waelkens, Hooijkaas, H, Westhovens, René, Liesbeth Maes, Vermeersch, P, Hooijkaas, H (Herbert), De Vlam, Kurt, Maes, L   +42 more
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Long noncoding RNA UCA1 promotes glutamine-driven anaplerosis of bladder cancer by interacting with hnRNP I/L to upregulate GPT2 expression

Translational Oncology, 2022
Long noncoding RNA urothelial cancer associated 1 (UCA1), initially identified in bladder cancer, is associated with multiple cellular processes, including metabolic reprogramming. However, its characteristics in the anaplerosis context of bladder cancer
Hua Zhao, Wenjing Wu, Xu Li, Wei Chen
doaj   +1 more source

Proteomic and 3D structure analyses highlight the C/D box snoRNP assembly mechanism and its control [PDF]

, 2014
In vitro, assembly of box C/D small nucleolar ribonucleoproteins (snoRNPs) involves the sequential recruitment of core proteins to snoRNAs. In vivo, however, assembly factors are required (NUFIP, BCD1, and the HSP90–R2TP complex), and it is unknown ...
Franck Vandermoere, Ahmad, Yasmeen, Bertrand, Edouard, Bérengère Pradet-Balade, Leonhardt, Heinrich, Charron, Christophe, Hallais, Marie, Christophe Charron, Marie Hallais, Vandermoere, Franck, Jonathan Bizarro, Pradet-Balade, Berengere, Christiane Branlant, Yasmeen Ahmad, Chagot, Marie-Eve, Céline Verheggen, Lamond, Angus; id_orcid, Heinrich Leonhardt, Branlant, Christiane, Edouard Bertrand, Lamond, Angus, Charpentier, Bruno, Angus Lamond, Xavier Manival, Manival, Xavier, Marie-Eve Chagot, Westman, Belinda, Boulon, Severine, Belinda Westman, Séverine Boulon, Verheggen, Celine, Bruno Charpentier, Bizarro, Jonathan   +32 more
core   +1 more source