Results 91 to 100 of about 214 (132)

Therapeutic Potential of Qilianxiaopi Formula: Targeting ADAM17-Mediated Chronic Inflammation in Atrophic Gastritis. [PDF]

Pharmaceuticals (Basel)
Du S, Wang T, Li Z, Li T, Miao Z, Chen Y, Zhu S, Wei W, Deng H.   +8 more
europepmc   +1 more source

Integrated Proteomics and Metabolomics of Safflower Petal Wilting and Seed Development. [PDF]

Biomolecules
Vincent D, Reddy P, Isenegger D.
europepmc   +1 more source

Network pharmacology analysis of Chandraprabha Vati: A new hope for the treatment of Metabolic Syndrome. [PDF]

J Ayurveda Integr Med
Dongre P, Majumdar A.
europepmc   +1 more source

Impact of Shenling Baizhu Powder on lipid profiles and body mass index in breast cancer patients under adjuvant chemotherapy: a retrospective study. [PDF]

Transl Cancer Res
Song J, Jin Y, Yu Q, Wu H, Li H, Lim GH, Antonini M, Gao X.   +7 more
europepmc   +1 more source

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Heterophyllin B ameliorates gastric cancer tumor growth through activating ER stress

Tissue and Cell, 2023
Gastric cancer (GC) is the third leading cause of cancer-related death worldwide. Heterophyllin B (HB) has been proved to be a potential drug in cancer treatment.In the current study, GC cells were treated with 0, 10, 25, or 50 μM of HB. Cell viability was determined by utilizing MTT assay.
Wanli, Xue, Rui, Sun, Zheng, Hao, Zhenzhen, Xing, Hongjie, Cheng, Lei, Shao   +5 more
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Protective effects of heterophyllin B against bleomycin-induced pulmonary fibrosis in mice via AMPK activation

European Journal of Pharmacology, 2022
Pulmonary fibrosis (PF) is a chronic interstitial lung disease with unknown etiology. In the present study, we evaluated the anti-fibrotic effects of heterophyllin B, a natural product from Radix Pseudostellariae having anti-inflammatory and tyrosinase inhibitory activities. In bleomycin (BLM)-induced PF mouse model, heterophyllin B treatments (5 or 20 
Wen, Shi, Jiatong, Hao, Yanliang, Wu, Chang, Liu, Kuniyoshi, Shimizu, Renshi, Li, Chaofeng, Zhang   +6 more
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Heterophyllin B, a cyclopeptide from Pseudostellaria heterophylla, enhances cognitive function via neurite outgrowth and synaptic plasticity

Phytotherapy Research, 2021
Neurite outgrowth‐induced construction of neural circuits and networks is responsible for memory generalization, consolidation, and retrieval. In this study, we found that the traditional Chinese medicine Pseudostellaria heterophylla promoted neurite regrowth and enhanced cognitive function in normal mice.
Zhiyou Yang, Cai Zhang, Xiaohong Li, Zhihui Ma, Yuewei Ge, Zhongji Qian, Cai Song   +6 more
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Heterophyllin B, a cyclopeptide from Pseudostellaria heterophylla, improves memory via immunomodulation and neurite regeneration in i.c.v.Aβ-induced mice

Food Research International, 2022
Pseudostellaria heterophylla, has historically been used as medicine food homology plant for thousand years in China. Our previous studies had indicated that daily intake of Pseudostellaria heterophylla extract enhanced cognitive memory. Herein, heterophyllin B (HET-B), a brain permeable cyclopeptide from Pseudostellaria heterophylla was determined ...
Jiahang, Deng, Xinyue, Feng, Longjian, Zhou, Chuantong, He, Huilin, Li, Juan, Xia, Yuewei, Ge, Yuntao, Zhao, Cai, Song, Lei, Chen, Zhiyou, Yang   +10 more
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Enzymatic cyclization of linear peptide to plant cyclopeptide heterophyllin B

Science in China Series B, 2006
The crude enzyme (PH-1) isolated from Pseudostellaria heterophylla by our group has catalyzed enzymatic cyclization of linear peptide NH2-Gly1-Gly2-Leu-Pro-Pro-Pro-Ile-Phe-COOH (4) into cyclopeptide heterophyllin B (HB) from plant for the first time.
Aiqun Jia, Xiang Li, Ninghua Tan, Xiaozhu Liu, Yuemao Shen, Jun Zhou   +5 more
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Heterophyllin B an Active Cyclopeptide Alleviates Dextran Sulfate Sodium‐Induced Colitis by Modulating Gut Microbiota and Repairing Intestinal Mucosal Barrier via AMPK Activation

Molecular Nutrition & Food Research, 2022
ScopeAdvances in pathology broaden the perception of the intimate interaction between gut microbiota dysbiosis and the pathogenesis of ulcerative colitis (UC), but the potential modulating roles remain to be elucidated.Methods and resultsDSS‐induced colitis is used to investigate the effect of Heterophyllin B (HB), a typical active cyclopeptide ...
Ce Chen, Han Liang, Jiaoyang Wang, Guoqing Ren, Renshi Li, Zheng‐Guo Cui, Chaofeng Zhang   +6 more
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