G Proteins and GPCRs in C. elegans Development: A Story of Mutual Infidelity
Many vital processes during C. elegans development, especially the establishment and maintenance of cell polarity in embryogenesis, are controlled by complex signaling pathways.
Daniel Matúš, Simone Prömel
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Global Analysis of Predicted G Protein-Coupled Receptor Genes in the Filamentous Fungus, Neurospora crassa. [PDF]
G protein-coupled receptors (GPCRs) regulate facets of growth, development, and environmental sensing in eukaryotes, including filamentous fungi. The largest predicted GPCR class in these organisms is the Pth11-related, with members similar to a protein ...
Ahrendt, Steven R +24 more
core
Heterotrimeric G-proteins, composed of Gα, Gβ, and Gγ subunits, regulate many fundamental processes in plants. In animals, ligand binding to seven transmembrane (7TM) cell surface receptors designated G-protein coupled receptors (GPCR) leads to ...
Justine Lorek +4 more
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Development of the mammalian axial skeleton requires signaling through the Gα i subfamily of heterotrimeric G proteins [PDF]
Nicholas W. Plummer +6 more
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Heterotrimeric G Protein-Mediated Signaling Is Involved in Stress-Mediated Growth Inhibition in Arabidopsis thaliana. [PDF]
Yang S, Jung S, Lee H.
europepmc +1 more source
The Interaction of Phospholipase C-{beta}3 with Shank2 Regulates mGluR-mediated Calcium Signal [PDF]
Phospholipase C-{beta} isozymes that are activated by G protein-coupled receptors (GPCR) and heterotrimeric G proteins carry a PSD-95/Dlg/ZO-1 (PDZ) domain binding motif at their C terminus. Through interactions with PDZ domains, this motif may endow the
Hwang, Jong-Ik +5 more
core
The α-Subunit of the Heterotrimeric G Protein G13Activates a Phospholipase D Isozyme by a Pathway Requiring Rho Family GTPases [PDF]
Steven G. Plonk +2 more
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Phosphorylation dynamics in a flg22-induced, heterotrimeric G-protein dependent signaling network in Arabidopsis thaliana reveals a candidate PP2A phosphatase involved in AtRGS1 trafficking [PDF]
Justin M. Watkins +12 more
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Functional Consequences of GPCR Heterodimerization: GPCRs as Allosteric Modulators
G Protein Coupled Receptors (GPCRs) represent the largest family of membrane proteins in the human genome, are the targets of approximately 25% of all marketed pharmaceuticals, and the focus of intensive research worldwide given that this superfamily of ...
Karla K.V. Haack, Nael A. McCarty
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Characterization of the heterotrimeric G protein gene families in Triticum aestivum and related species. [PDF]
Gawande ND +3 more
europepmc +1 more source

