Results 91 to 100 of about 18,851,748 (235)
Frontiers in Genetics, 2019 Characterizing the complete genomic structure of complex microbial communities would represent a key step toward the understanding of their diversity, dynamics, and evolution.
Lyam Baudry +11 more
doaj +1 more source
Hi-C contact map of the chromosomal pseudomolecules SOL_r2.0_pseudomolecule.
Hi-C contact map of the chromosomal pseudomolecules SOL_r2.0_pseudomolecule.
Yutaka Suzuki (1379) +10 more
core +1 more source
Hi-C library statistics for different datasets used in this paper.
, 2019 Mapped read pairs denote the total number of Hi-C read pairs aligned before mapping quality filtering. Intra-contig read pairs account for the read pairs where both the reads align to same contig and inter-contig read pairs account for the read pairs ...
Arang Rhie (7296419) +7 more
core +1 more source
Synteny and rearrangement alignments - Hi-C
, 2023 SyRI output files for all pairs of genome alignments for E. melliodora Hi-C analysis. Each file contains the syntenc and rearranged sequences between each pair of genomes.
Scott Ferguson (9952223)
core +1 more source
From Adult to Adolescent: Alignment in Clinical Trials and Outcomes in Axial Spondyloarthritis
Arthritis Care &Research, EarlyView.Spondyloarthritis (SpA) is a group of chronic inflammatory diseases encompassing axial and peripheral forms, with up to 20% of patients developing symptoms before age 16. Despite this substantial pediatric burden, treatment options for juvenile‐onset SpA (JSpA), particularly those with axial disease (axJSpA), remain limited.
Pamela F. Weiss +9 more
wiley +1 more source
HiCcompare: an R-package for joint normalization and comparison of HI-C datasets
BMC Bioinformatics, 2018 Background Changes in spatial chromatin interactions are now emerging as a unifying mechanism orchestrating the regulation of gene expression. Hi-C sequencing technology allows insight into chromatin interactions on a genome-wide scale.
John C. Stansfield +3 more
doaj +1 more source
Wheat chromatin architecture is organized in genome territories and transcription factories
Genome Biology, 2020 Background Polyploidy is ubiquitous in eukaryotic plant and fungal lineages, and it leads to the co-existence of several copies of similar or related genomes in one nucleus.
Lorenzo Concia +25 more
doaj +1 more source
Arthritis Care &Research, EarlyView.Objective Orofacial manifestations are significantly impactful in patients with systemic sclerosis (SSc) yet remain understudied, with no dedicated clinical guidelines to inform their management. Methods An international online survey comprised38 questions addressing orofacial manifestations of SSc, including patients’ confidence in their treating ...
Eleni Deligianni +4 more
wiley +1 more source
Principles of Chromosome Architecture Revealed by Hi-C [PDF]
Trends in Biochemical Sciences, 2018 Chromosomes are folded and compacted in interphase nuclei, but the molecular basis of this folding is poorly understood. Chromosome conformation capture methods, such as Hi-C, combine chemical crosslinking of chromatin with fragmentation, DNA ligation, and high-throughput DNA sequencing to detect neighboring loci genome-wide.
openaire +2 more sources
Arthritis Care &Research, EarlyView.Objective To assess the validity of the Patient‐Reported Outcomes Measurement Information System (PROMIS) Pediatric measures in patients with chronic nonbacterial osteomyelitis (CNO). Methods Within the longitudinal patient registry of CNO, English‐speaking patients aged 8 years and older self‐reported PROMIS Pediatric measures of fatigue, pain ...
Mary M. Eckert +43 more
wiley +1 more source