Results 71 to 80 of about 14,864,540 (284)

Hi-PACE/hipace: v22.11

, 2022
Dependencies AMReX: release 22.11 openPMD-api: release 0.14.5 What's Changed Fix enforcePeriodic call for AMReX PR 2950 by @atmyers in https://github.com/Hi-PACE/hipace/pull/794 Multigrid smoother by @WeiqunZhang in https://github.com/Hi-PACE/hipace ...
Lehe, Remi, Sinn, Alexander, Diederichs, Severin, Zhang, Weiqun, Huebl, Axel, Myers, Andrew, Thévenet, Maxence   +6 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Hi-PACE/hipace: v22.06

, 2022
Dependencies AMReX: release 22.06 openPMD-api: release 0.14.4 What's Changed Open Boundaries by @AlexanderSinn in https://github.com/Hi-PACE/hipace/pull/666 fix beam particle ID in IO; save ID directly, CPU information is outdated by @SeverinDiederichs ...
Lehe, Remi, Sinn, Alexander, Diederichs, Severin, Zhang, Weiqun, Huebl, Axel, Myers, Andrew, Thévenet, Maxence   +6 more
core   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

HI-FRIENDS participation in the SKA Data Challenge 2

, 2021
This repository contains the workflow used to find and characterize the HI sources in the data cube of the SKA Data Challenge 2. This is developed by the HI-FRIENDS team.
Darriba, Laura, Parra, Manuel, Kamphuis, Peter, Alberdi, Antonio, Garrido, Julian, Márquez, Isabel, Józsa, Gyula, Sorgho, Amidou, Herranz, Diego, Jones, Michael, Akhlaghi, Mohammad, Kleiner, Dane, Moldon, Javier, Cannon, John, Gomez, Jose Francisco, Verdes-Montenegro, Lourdes, Sanchez, Susana   +16 more
core   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Hi-PACE/hipace: v23.05

, 2023
Dependencies AMReX: release 23.05 openPMD-api: release 0.15.1 What's Changed CI: macOS Only One by @ax3l in https://github.com/Hi-PACE/hipace/pull/881 On dev branch, we build on top of amrex dev branch by @MaxThevenet in https://github.com/Hi-PACE ...
Lehe, Remi, Sinn, Alexander, Diederichs, Severin, Zhang, Weiqun, Huebl, Axel, Myers, Andrew, Thévenet, Maxence   +6 more
core   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

FEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata, Yoichi Sakai, Keisuke Tanaka, Etsuro Yoshimura, Ken Kitano, Morio Ishikawa, Tadahiro Nakamoto, Tsutomu Takayama, Hirofumi Inoue, Kaho Nomura, Tomonori Suzuki, Masataka Uchino, Akira Abe, Youichi Niimura   +13 more
wiley   +1 more source

Learning Micro-C from Hi-C with diffusion models.

PLoS Computational Biology
In the last few years, Micro-C has shown itself as an improved alternative to Hi-C. It replaced the restriction enzymes in Hi-C assays with micrococcal nuclease (MNase), resulting in capturing nucleosome resolution chromatin interactions.
Tong Liu, Hao Zhu, Zheng Wang
doaj   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source