Results 61 to 70 of about 18,851,748 (235)

Softshell turtle genome assemblies scaffolded with Hi-C data

open access: yes, 2019
This dataset, associated with our prospected publication by Kadota et al., contains softshell turtle genome assemblies based on Hi-C scaffolding. See the file "Assembly_ID.xlsx" for details of the combinations of tissue, enzyme, scaffolding program and ...
Phyloinformatics Lab in RIKEN Kobe (4815111)
core   +1 more source

Hi-PACE/hipace: v22.06

open access: yes, 2022
Dependencies AMReX: release 22.06 openPMD-api: release 0.14.4 What's Changed Open Boundaries by @AlexanderSinn in https://github.com/Hi-PACE/hipace/pull/666 fix beam particle ID in IO; save ID directly, CPU information is outdated by @SeverinDiederichs ...
Lehe, Remi   +6 more
core   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

open access: yesFEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia   +9 more
wiley   +1 more source

DeepHiC: A generative adversarial network for enhancing Hi-C data resolution.

open access: yesPLoS Computational Biology, 2020
Hi-C is commonly used to study three-dimensional genome organization. However, due to the high sequencing cost and technical constraints, the resolution of most Hi-C datasets is coarse, resulting in a loss of information and biological interpretability ...
Hao Hong   +14 more
doaj   +1 more source

A global high-density chromatin interaction network reveals functional long-range and trans-chromosomal relationships

open access: yesGenome Biology, 2022
Background Chromatin contacts are essential for gene-expression regulation; however, obtaining a high-resolution genome-wide chromatin contact map is still prohibitively expensive owing to large genome sizes and the quadratic scale of pairwise data ...
Ruchi Lohia, Nathan Fox, Jesse Gillis
doaj   +1 more source

Hi-C data reveals interactions within and among chromosomes.

open access: yes, 2018
A. Each element of the matrix reflects the frequency of contacts between two genomic windows in an exemplar region of chromosome 3. Repeat density and the locations of AT-rich regions (blue) are plotted below the matrix, as in Fig 2.
Daniel Berry (3482828)   +9 more
core   +1 more source

Hi-PACE/hipace: v22.12

open access: yes, 2022
Dependencies AMReX: release 22.12 openPMD-api: release 0.14.5 What's Changed Update version number before release by @MaxThevenet in https://github.com/Hi-PACE/hipace/pull/812 Fix invalid CUDA device function error in HPMG by @AlexanderSinn in https ...
Lehe, Remi   +6 more
core   +1 more source

SPG4 and Dementia: Expanding the Clinical Spectrum

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza   +19 more
wiley   +1 more source

Massively multiplex single-cell Hi-C [PDF]

open access: yesNature Methods, 2017
We present single-cell combinatorial indexed Hi-C (sciHi-C), a method that applies combinatorial cellular indexing to chromosome conformation capture. In this proof of concept, we generate and sequence six sciHi-C libraries comprising a total of 10,696 single cells.
Vijay Ramani   +8 more
openaire   +2 more sources

Stabilization by fusion to the C-terminus of hyperthermophile Sulfolobus tokodaii RNase HI: a possibility of protein stabilization tag. [PDF]

open access: yesPLoS ONE, 2011
RNase HI from the hyperthermophile Sulfolobus tokodaii (Sto-RNase HI) is stabilized by its C-terminal residues. In this work, the stabilization effect of the Sto-RNase HI C-terminal residues was investigated in detail by thermodynamic measurements of the
Kazufumi Takano   +6 more
doaj   +1 more source

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