Results 61 to 70 of about 14,864,540 (284)

Analyses of significant chromatin interactions identified by Fit-Hi-C software.

open access: yes, 2020
(a) Three representative sub-regions (1 Mb × 1 Mb) from chromosomes 17 and 22 (GM12878 cell line), with significant loci-pairs (cut-off is the 0.5 percentile of q-values) being marked with yellow points in the upper triangle of the heatmaps.
Guifang Du (8479452)   +14 more
core   +1 more source

Hi-PACE/hipace: v22.12

open access: yes, 2022
Dependencies AMReX: release 22.12 openPMD-api: release 0.14.5 What's Changed Update version number before release by @MaxThevenet in https://github.com/Hi-PACE/hipace/pull/812 Fix invalid CUDA device function error in HPMG by @AlexanderSinn in https ...
Lehe, Remi   +6 more
core   +1 more source

Massively multiplex single-cell Hi-C [PDF]

open access: yesNature Methods, 2017
We present single-cell combinatorial indexed Hi-C (sciHi-C), a method that applies combinatorial cellular indexing to chromosome conformation capture. In this proof of concept, we generate and sequence six sciHi-C libraries comprising a total of 10,696 single cells.
Vijay Ramani   +8 more
openaire   +2 more sources

Modeling the 3D genome of plants

open access: yesNucleus, 2021
Chromosomes are the carriers of inheritable traits and define cell function and development. This is not only based on the linear DNA sequence of chromosomes but also on the additional molecular information they are associated with, including the ...
Marco Di Stefano, Hans-Wilhelm Nützmann
doaj   +1 more source

Hi-PACE/hipace: v22.07

open access: yes, 2022
Dependencies AMReX: release 22.07 openPMD-api: release 0.14.5 What's Changed Fix debug crash from empty multifab by @AlexanderSinn in https://github.com/Hi-PACE/hipace/pull/752 [mini] gpu synchronize after beam particle sort per slice by ...
Lehe, Remi   +6 more
core   +1 more source

A Multigraph-Based Representation of Hi-C Data

open access: yesGenes, 2022
Chromatin–chromatin interactions and three-dimensional (3D) spatial structures are involved in transcriptional regulation and have a decisive role in DNA replication and repair. To understand how individual genes and their regulatory elements function within the larger genomic context, and how the genome reacts to environmental stimuli, the linear ...
Diána Makai   +3 more
openaire   +3 more sources

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Hi-PACE/hipace: v22.09

open access: yes, 2022
Dependencies AMReX: release 22.09 openPMD-api: release 0.14.5 What's Changed Fix adaptive time step by @SeverinDiederichs in https://github.com/Hi-PACE/hipace/pull/771 ensure that argument of sqrt in adaptive time step is positive by @SeverinDiederichs ...
Lehe, Remi   +6 more
core   +1 more source

Targeted DNase Hi-C

open access: yes, 2020
Technology advance during the past decade has greatly expanded our understanding of the higher-order structure of the genome. The various chromosome conformation capture (3C)-based techniques such as Hi-C have provided the most widely used tools for interrogating three-dimensional (3D) genome organization. We recently developed a Hi-C variant, DNase Hi-
openaire   +3 more sources

Genome Improvement and Core Gene Set Refinement of Fugacium kawagutii

open access: yesMicroorganisms, 2020
Cataloging an accurate functional gene set for the Symbiodiniaceae species is crucial for addressing biological questions of dinoflagellate symbiosis with corals and other invertebrates. To improve the gene models of Fugacium kawagutii, we conducted high-
Tangcheng Li   +6 more
doaj   +1 more source

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