Results 41 to 50 of about 20,056,738 (185)
Genome Improvement and Core Gene Set Refinement of Fugacium kawagutii
Cataloging an accurate functional gene set for the Symbiodiniaceae species is crucial for addressing biological questions of dinoflagellate symbiosis with corals and other invertebrates. To improve the gene models of Fugacium kawagutii, we conducted high-
Tangcheng Li +6 more
doaj +1 more source
Role of lamins in 3D genome organization and global gene expression
Genome-wide mapping of lamin-B1-genome interactions has shown that gene-poor and transcriptionally inactive genomic regions are associated with the nuclear lamina.
Youngjo Kim, Xiaobin Zheng, Yixian Zheng
doaj +1 more source
Overview of Hi-C and Capture Hi-C datasets presented in this study.
Overview of Hi-C and Capture Hi-C datasets presented in this study.
Anne M. Molitor (8335128) +10 more
core +1 more source
HUGIn: Hi-C Unifying Genomic Interrogator [PDF]
Abstract Motivation High throughput chromatin conformation capture (3C) technologies, such as Hi-C and ChIA-PET, have the potential to elucidate the functional roles of non-coding variants. However, most of published genome-wide unbiased chromatin organization studies have used cultured cell ...
Joshua S. Martin +7 more
openaire +3 more sources
A Multigraph-Based Representation of Hi-C Data
Chromatin–chromatin interactions and three-dimensional (3D) spatial structures are involved in transcriptional regulation and have a decisive role in DNA replication and repair. To understand how individual genes and their regulatory elements function within the larger genomic context, and how the genome reacts to environmental stimuli, the linear ...
Diána Makai +3 more
openaire +3 more sources
Data for the HAdV55 RNA-seq and Hi-C
Analysis data for the RNA-seq and Hi-C about adenovirus and A549 cells ...
Kaiying Wang (14583608)
core +1 more source
DeepHiC: A generative adversarial network for enhancing Hi-C data resolution.
Hi-C is commonly used to study three-dimensional genome organization. However, due to the high sequencing cost and technical constraints, the resolution of most Hi-C datasets is coarse, resulting in a loss of information and biological interpretability ...
Hao Hong +14 more
doaj +1 more source
Software tools for visualizing Hi-C data [PDF]
Abstract Recently developed, high-throughput assays for measuring the three-dimensional configuration of DNA in the nucleus have provided unprecedented insights into the relationship between DNA 3D configuration and function. However, accurate interpretation of data from assays such as ChIA-PET and Hi-C is challenging because the data ...
Galip Gürkan Yardımcı +1 more
openaire +2 more sources
Technology advance during the past decade has greatly expanded our understanding of the higher-order structure of the genome. The various chromosome conformation capture (3C)-based techniques such as Hi-C have provided the most widely used tools for interrogating three-dimensional (3D) genome organization. We recently developed a Hi-C variant, DNase Hi-
openaire +3 more sources

