Results 41 to 50 of about 18,851,748 (235)
Dependencies AMReX: release 23.07 openPMD-api: release 0.15.1 What's Changed Replace rho field with rho - jz/c by @AlexanderSinn in https://github.com/Hi-PACE/hipace/pull/940 CI: apt retry and new Easyinstall link by @AlexanderSinn in https://github.com/
Lehe, Remi +6 more
core +1 more source
Hi-C 2.0: An optimized Hi-C procedure for high-resolution genome-wide mapping of chromosome conformation [PDF]
ABSTRACT Chromosome conformation capture-based methods such as Hi-C have become mainstream techniques for the study of the 3D organization of genomes. These methods convert chromatin interactions reflecting topological chromatin structures into digital information (counts of pair-wise interactions). Here, we describe an updated protocol
Houda Belaghzal +2 more
openaire +3 more sources
Hi–C interaction graph analysis reveals the impact of histone modifications in chromatin shape
Chromosome conformation capture experiments such as Hi–C map the three-dimensional spatial organization of genomes in a genome-wide scale. Even though Hi–C interactions are not biased towards any of the histone modifications, previous analysis has ...
Emre Sefer
doaj +1 more source
Hi-C as a new technique for detecting large-scale SVs.
(A) The expected alteration to chromatin interaction frequencies for different types of SVs. (B) The Hi-C map is shown a validated deletion event in K562 cell line.
Junping Li (614144) +2 more
core +1 more source
Role of lamins in 3D genome organization and global gene expression
Genome-wide mapping of lamin-B1-genome interactions has shown that gene-poor and transcriptionally inactive genomic regions are associated with the nuclear lamina.
Youngjo Kim, Xiaobin Zheng, Yixian Zheng
doaj +1 more source
HUGIn: Hi-C Unifying Genomic Interrogator [PDF]
Abstract Motivation High throughput chromatin conformation capture (3C) technologies, such as Hi-C and ChIA-PET, have the potential to elucidate the functional roles of non-coding variants. However, most of published genome-wide unbiased chromatin organization studies have used cultured cell ...
Joshua S. Martin +7 more
openaire +3 more sources
A Multigraph-Based Representation of Hi-C Data
Chromatin–chromatin interactions and three-dimensional (3D) spatial structures are involved in transcriptional regulation and have a decisive role in DNA replication and repair. To understand how individual genes and their regulatory elements function within the larger genomic context, and how the genome reacts to environmental stimuli, the linear ...
Diána Makai +3 more
openaire +3 more sources
Dependencies AMReX: release 22.03 openPMD-api: release 0.14.4 What's Changed update fixed ppc beams and a few other things in documentation by @SeverinDiederichs in https://github.com/Hi-PACE/hipace/pull/661 fix typo in table in documentation by ...
Lehe, Remi +6 more
core +1 more source
Analyses of significant chromatin interactions identified by Fit-Hi-C software.
(a) Three representative sub-regions (1 Mb × 1 Mb) from chromosomes 17 and 22 (GM12878 cell line), with significant loci-pairs (cut-off is the 0.5 percentile of q-values) being marked with yellow points in the upper triangle of the heatmaps.
Guifang Du (8479452) +14 more
core +1 more source

