Results 21 to 30 of about 243,805 (237)
PLoS Computational Biology, 2022 Hi-C is a genome-wide chromosome conformation capture technology that detects interactions between pairs of genomic regions and exploits higher order chromatin structures.
Hamid Alinejad-Rokny +6 more
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Frontiers in Genetics, 2023 Sericinus montelus (Lepidoptera, Papilionidae, Parnassiinae) is a high-value ornamental swallowtail butterfly species widely distributed in Northern and Central China, Japan, Korea, and Russia.
Jingjing Li +9 more
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Genome Biology, 2020 Hi-C exploits contact frequencies between pairs of loci to bridge and order contigs during genome assembly, resulting in chromosome-level assemblies. Because few robust programs are available for this type of data, we developed instaGRAAL, a complete ...
Lyam Baudry +12 more
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Cellular reprogramming is driven by widespread rewiring of promoter-enhancer interactions
BMC Biology, 2023 Background Long-range interactions between promoters and cis-regulatory elements, such as enhancers, play critical roles in gene regulation. However, the role of three-dimensional (3D) chromatin structure in orchestrating changes in transcriptional ...
Miao Wang +5 more
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GrapHi-C: graph-based visualization of Hi-C datasets
BMC Research Notes, 2018 Objectives Hi-C is a proximity-based ligation reaction used to detect regions of the genome that are close in 3D space (or “interacting”). Typically, results from Hi-C experiments (contact maps) are visualized as heatmaps or Circos plots.
Kimberly MacKay +2 more
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SRHiC: A Deep Learning Model to Enhance the Resolution of Hi-C Data
Frontiers in Genetics, 2020 Hi-C data is important for studying chromatin three-dimensional structure. However, the resolution of most existing Hi-C data is generally coarse due to sequencing cost.
Zhilan Li, Zhiming Dai, Zhiming Dai
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Influence of human peripheral blood samples preprocessing on the quality of Hi-C libraries
Вавиловский журнал генетики и селекции, 2023 The genome-wide variant of the chromatin conformation capture technique (Hi-C) is a powerful tool for revealing patterns of genome spatial organization, as well as for understanding the effects of their disturbance on disease development. In addition, Hi-
M. M. Gridina +8 more
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eLife, 2014 Genomic analyses of microbial populations in their natural environment remain limited by the difficulty to assemble full genomes of individual species.
Martial Marbouty +5 more
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Modeling the 3D genome of plants
Nucleus, 2021 Chromosomes are the carriers of inheritable traits and define cell function and development. This is not only based on the linear DNA sequence of chromosomes but also on the additional molecular information they are associated with, including the ...
Marco Di Stefano, Hans-Wilhelm Nützmann
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Genome Improvement and Core Gene Set Refinement of Fugacium kawagutii
Microorganisms, 2020 Cataloging an accurate functional gene set for the Symbiodiniaceae species is crucial for addressing biological questions of dinoflagellate symbiosis with corals and other invertebrates. To improve the gene models of Fugacium kawagutii, we conducted high-
Tangcheng Li +6 more
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