Results 21 to 30 of about 14,864,540 (284)
Measuring the reproducibility and quality of Hi-C data
Genome Biology, 2019 Background Hi-C is currently the most widely used assay to investigate the 3D organization of the genome and to study its role in gene regulation, DNA replication, and disease.
Galip Gürkan Yardımcı +18 more
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Efficient iterative Hi-C scaffolder based on N-best neighbors
BMC Bioinformatics, 2021 Background Efficient and effective genome scaffolding tools are still in high demand for generating reference-quality assemblies. While long read data itself is unlikely to create a chromosome-scale assembly for most eukaryotic species, the inexpensive ...
Dengfeng Guan +5 more
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Motif-Hi-C: A motif-based framework for rapid quality control of Hi-C data. [PDF]
aBIOTECHKong D +7 more
europepmc +2 more sources
G3: Genes, Genomes, Genetics, 2020 Chromosome level assemblies are accumulating in various taxonomic groups including mosquitoes. However, even in the few reference-quality mosquito assemblies, a significant portion of the heterochromatic regions including telomeres remain unresolved ...
Austin Compton +12 more
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Cold Spring Harbor Protocols, 2015 Hi-C enables simultaneous detection of interaction frequencies between all possible pairs of restriction fragments in the genome. The Hi-C method is based on chromosome conformation capture (3C), which uses formaldehyde cross-linking to fix chromatin regions that interact in three-dimensional space, irrespective of their genomic locations.
Belton, Jon-Matthew, Dekker, Job
openaire +3 more sources
Frontiers in Plant Science, 2023 High-throughput chromosome conformation capture (Hi-C) technology has been applied to explore the chromatin interactions and shed light on the biological functions of three-dimensional genomic features.
Jin Han +8 more
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Computational Processing and Quality Control of Hi-C, Capture Hi-C and Capture-C Data [PDF]
Genes, 2019 Hi-C, capture Hi-C (CHC) and Capture-C have contributed greatly to our present understanding of the three-dimensional organization of genomes in the context of transcriptional regulation by characterizing the roles of topological associated domains, enhancer promoter loops and other three-dimensional genomic interactions.
Peter Hansen +6 more
openaire +4 more sources
BMC Genomics, 2020 Background Hi-C is a molecular biology technique to understand the genome spatial structure. However, data obtained from Hi-C experiments is biased. Therefore, several methods have been developed to model Hi-C data and identify significant interactions ...
Saman Khakmardan +4 more
doaj +1 more source
Energetics of Hi-C EUV brightenings [PDF]
Astronomy & Astrophysics, 2018 We study the thermal structure and energetics of the point-like extreme ultraviolet (EUV) brightenings within a system of fan loops observed in the active region AR 11520. These brightenings were simultaneously observed on 2012 July 11 by the High-resolution Coronal (Hi-C) imager and the Atmospheric Imaging Assembly (AIA) on board the Solar Dynamics ...
Srividya Subramanian +4 more
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Hi-C read-pair classifications.
, 2021 A reference-based classification scheme for read-pairs generated by the Hi-C protocol has previously been devised [11, 13]. Regardless of orientation, read-pairs are considered valid if two or more intervening enzymatic cut-site exist between them ...
Matthew Z. DeMaere (6404834) +1 more
core +1 more source