Results 11 to 20 of about 243,805 (237)

Motif-Hi-C: A motif-based framework for rapid quality control of Hi-C data [PDF]

open access: yesaBIOTECH
Dashuai Kong   +7 more
openaire   +2 more sources

Efficient iterative Hi-C scaffolder based on N-best neighbors

open access: yesBMC Bioinformatics, 2021
Background Efficient and effective genome scaffolding tools are still in high demand for generating reference-quality assemblies. While long read data itself is unlikely to create a chromosome-scale assembly for most eukaryotic species, the inexpensive ...
Dengfeng Guan   +5 more
doaj   +1 more source

The Beginning of the End: A Chromosomal Assembly of the New World Malaria Mosquito Ends with a Novel Telomere

open access: yesG3: Genes, Genomes, Genetics, 2020
Chromosome level assemblies are accumulating in various taxonomic groups including mosquitoes. However, even in the few reference-quality mosquito assemblies, a significant portion of the heterochromatic regions including telomeres remain unresolved ...
Austin Compton   +12 more
doaj   +1 more source

Hi-C in Budding Yeast [PDF]

open access: yesCold Spring Harbor Protocols, 2015
Hi-C enables simultaneous detection of interaction frequencies between all possible pairs of restriction fragments in the genome. The Hi-C method is based on chromosome conformation capture (3C), which uses formaldehyde cross-linking to fix chromatin regions that interact in three-dimensional space, irrespective of their genomic locations.
Belton, Jon-Matthew, Dekker, Job
openaire   +3 more sources

An upgraded method of high-throughput chromosome conformation capture (Hi-C 3.0) in cotton (Gossypium spp.)

open access: yesFrontiers in Plant Science, 2023
High-throughput chromosome conformation capture (Hi-C) technology has been applied to explore the chromatin interactions and shed light on the biological functions of three-dimensional genomic features.
Jin Han   +8 more
doaj   +1 more source

Computational Processing and Quality Control of Hi-C, Capture Hi-C and Capture-C Data [PDF]

open access: yesGenes, 2019
Hi-C, capture Hi-C (CHC) and Capture-C have contributed greatly to our present understanding of the three-dimensional organization of genomes in the context of transcriptional regulation by characterizing the roles of topological associated domains, enhancer promoter loops and other three-dimensional genomic interactions.
Peter Hansen   +6 more
openaire   +4 more sources

MHiC, an integrated user-friendly tool for the identification and visualization of significant interactions in Hi-C data

open access: yesBMC Genomics, 2020
Background Hi-C is a molecular biology technique to understand the genome spatial structure. However, data obtained from Hi-C experiments is biased. Therefore, several methods have been developed to model Hi-C data and identify significant interactions ...
Saman Khakmardan   +4 more
doaj   +1 more source

Energetics of Hi-C EUV brightenings [PDF]

open access: yesAstronomy & Astrophysics, 2018
We study the thermal structure and energetics of the point-like extreme ultraviolet (EUV) brightenings within a system of fan loops observed in the active region AR 11520. These brightenings were simultaneously observed on 2012 July 11 by the High-resolution Coronal (Hi-C) imager and the Atmospheric Imaging Assembly (AIA) on board the Solar Dynamics ...
Srividya Subramanian   +4 more
openaire   +3 more sources

Galaxy HiCExplorer 3: a web server for reproducible Hi-C, capture Hi-C and single-cell Hi-C data analysis, quality control and visualization [PDF]

open access: yesNucleic Acids Research, 2020
AbstractThe Galaxy HiCExplorer provides a web service at https://hicexplorer.usegalaxy.eu. It enables the integrative analysis of chromosome conformation by providing tools and computational resources to pre-process, analyse and visualize Hi-C, Capture Hi-C (cHi-C) and single-cell Hi-C (scHi-C) data.
Joachim Wolff   +6 more
openaire   +4 more sources

Role of the Nuclear Lamina in Age-Associated Nuclear Reorganization and Inflammation

open access: yesCells, 2020
Aging is characterized by the gradual loss of tissue function and integrity. Activation of inflammatory responses accelerates the deterioration of cells and tissues.
Lidya Kristiani, Miri Kim, Youngjo Kim
doaj   +1 more source

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