Results 31 to 40 of about 14,864,540 (284)

Galaxy HiCExplorer 3: a web server for reproducible Hi-C, capture Hi-C and single-cell Hi-C data analysis, quality control and visualization [PDF]

open access: yesNucleic Acids Research, 2020
AbstractThe Galaxy HiCExplorer provides a web service at https://hicexplorer.usegalaxy.eu. It enables the integrative analysis of chromosome conformation by providing tools and computational resources to pre-process, analyse and visualize Hi-C, Capture Hi-C (cHi-C) and single-cell Hi-C (scHi-C) data.
Joachim Wolff   +6 more
openaire   +4 more sources

Spectral and deep learning approaches to Hi-C data analysis [PDF]

open access: yes, 2021
Hi-C matrices describe the genome-wide contact probability between chromatin loci. The comparison of Hi-C matrices is important both to assess the reproducibility in biological replicates and to find significant differences between non replicates from ...
Franzini, Stefano
core  

Hi-C maps, 3D communities, and domains.

open access: yes, 2023
(a) Hi-C maps where the red-to-blue pixel colors are a proxy for short-to-long 3D distances. The squares decorating the map’s diagonals represent GenLouvain-derived 3D communities for three γ values (0.5, 0.6, and 0.7).
Dolores Bernenko (16528426)   +3 more
core   +1 more source

Role of the Nuclear Lamina in Age-Associated Nuclear Reorganization and Inflammation

open access: yesCells, 2020
Aging is characterized by the gradual loss of tissue function and integrity. Activation of inflammatory responses accelerates the deterioration of cells and tissues.
Lidya Kristiani, Miri Kim, Youngjo Kim
doaj   +1 more source

MaxHiC: A robust background correction model to identify biologically relevant chromatin interactions in Hi-C and capture Hi-C experiments.

open access: yesPLoS Computational Biology, 2022
Hi-C is a genome-wide chromosome conformation capture technology that detects interactions between pairs of genomic regions and exploits higher order chromatin structures.
Hamid Alinejad-Rokny   +6 more
doaj   +1 more source

The statistical summaries of significant interactions identified by MaxHiC, GOTHiC, CHiCAGO, Fit-Hi-C, Fit-Hi-C2, and HiCDC+ on the Mifsud GM12878 capture Hi-C library at fragments 5kb and 10kb.

open access: yes, 2022
As the table shows, the average read count of significant interactions identified by MaxHiC are much higher than those identified by CHiCAGO, GOTHiC, Fit-Hi-C, Fit-HiC2 and HiCDC+. (XLSX)
Hamid Alinejad-Rokny (518381)   +6 more
core   +1 more source

Hi-C interaction map on GM12878 HiC data.

open access: yes, 2022
Heatmap showing the raw read count of interactions at 5k bins of chr21 (36000kb to 39500kb) (same region as S10 Fig in the cLoops paper [43] on the GM12878 Hi-C dataset in Rao et al. [5]. The heatmap is colored based on the log of read count. Significant
Hamid Alinejad-Rokny (518381)   +6 more
core   +1 more source

instaGRAAL: chromosome-level quality scaffolding of genomes using a proximity ligation-based scaffolder

open access: yesGenome Biology, 2020
Hi-C exploits contact frequencies between pairs of loci to bridge and order contigs during genome assembly, resulting in chromosome-level assemblies. Because few robust programs are available for this type of data, we developed instaGRAAL, a complete ...
Lyam Baudry   +12 more
doaj   +1 more source

Cellular reprogramming is driven by widespread rewiring of promoter-enhancer interactions

open access: yesBMC Biology, 2023
Background Long-range interactions between promoters and cis-regulatory elements, such as enhancers, play critical roles in gene regulation. However, the role of three-dimensional (3D) chromatin structure in orchestrating changes in transcriptional ...
Miao Wang   +5 more
doaj   +1 more source

Hi-PACE/hipace: v22.02

open access: yes, 2022
Dependencies AMReX: release 22.02 openPMD-api: release 0.14.3 What's Changed Include destructor of hipace in profiler by @AlexanderSinn in https://github.com/Hi-PACE/hipace/pull/639 Pass the number of ghost cells to amrex::MultiFab::setVal, etc.
Lehe, Remi   +6 more
core   +1 more source

Home - About - Disclaimer - Privacy