Results 81 to 90 of about 14,864,540 (284)

MetaTOR: A Computational Pipeline to Recover High-Quality Metagenomic Bins From Mammalian Gut Proximity-Ligation (meta3C) Libraries

Frontiers in Genetics, 2019
Characterizing the complete genomic structure of complex microbial communities would represent a key step toward the understanding of their diversity, dynamics, and evolution.
Lyam Baudry, Lyam Baudry, Lyam Baudry, Théo Foutel-Rodier, Théo Foutel-Rodier, Théo Foutel-Rodier, Agnès Thierry, Agnès Thierry, Romain Koszul, Romain Koszul, Martial Marbouty, Martial Marbouty   +11 more
doaj   +1 more source

Stabilization by fusion to the C-terminus of hyperthermophile Sulfolobus tokodaii RNase HI: a possibility of protein stabilization tag. [PDF]

PLoS ONE, 2011
RNase HI from the hyperthermophile Sulfolobus tokodaii (Sto-RNase HI) is stabilized by its C-terminal residues. In this work, the stabilization effect of the Sto-RNase HI C-terminal residues was investigated in detail by thermodynamic measurements of the
Kazufumi Takano, Tomohiro Okamoto, Jun Okada, Shun-ichi Tanaka, Clement Angkawidjaja, Yuichi Koga, Shigenori Kanaya   +6 more
doaj   +1 more source

Softshell turtle genome assemblies scaffolded with Hi-C data

, 2019
This dataset, associated with our prospected publication by Kadota et al., contains softshell turtle genome assemblies based on Hi-C scaffolding. See the file "Assembly_ID.xlsx" for details of the combinations of tissue, enzyme, scaffolding program and ...
Phyloinformatics Lab in RIKEN Kobe (4815111)
core   +1 more source

Brainstem and Cerebellar Volume Loss and Associated Clinical Features in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Progressive Supranuclear Palsy (PSP) is a neurodegenerative ‘tauopathy’ with predominating pathology in the basal ganglia and midbrain. Caudal tau spread frequently implicates the cerebellum; however, the pattern of atrophy remains equivocal.
Chloe Spiegel, Timothy P. Siejka, Cassandra Marotta, Josh J. Y. Lee, Kelly Bertram, Terence J. O'Brien, Meng Law, Lucy Vivash, Ian H. Harding   +8 more
wiley   +1 more source

MaxHiC: robust estimation of chromatin interaction frequency in Hi-C and capture Hi-C experiments [PDF]

, 2020
Abstract Hi-C is a genome-wide chromosome conformation capture technology that detects interactions between pairs of genomic regions, and exploits higher order chromatin structures. Conceptually Hi-C data counts interaction frequencies between every position in the genome and every other position.
Alinejad-Rokny, Hamid, Ghavami, Rassa, Rabiee, Hamid R., Rezaei, Narges, Tam, Kin Tung, Forrest, Alistair R. R.   +5 more
openaire   +1 more source

HiCcompare: an R-package for joint normalization and comparison of HI-C datasets

BMC Bioinformatics, 2018
Background Changes in spatial chromatin interactions are now emerging as a unifying mechanism orchestrating the regulation of gene expression. Hi-C sequencing technology allows insight into chromatin interactions on a genome-wide scale.
John C. Stansfield, Kellen G. Cresswell, Vladimir I. Vladimirov, Mikhail G. Dozmorov   +3 more
doaj   +1 more source

Hi-C data reveals interactions within and among chromosomes.

, 2018
A. Each element of the matrix reflects the frequency of contacts between two genomic windows in an exemplar region of chromosome 3. Repeat density and the locations of AT-rich regions (blue) are plotted below the matrix, as in Fig 2.
Daniel Berry (3482828), David J. Winter (841851), Carolyn A. Young (383621), Ivan Liachko (248887), Pierre-Yves Dupont (4423090), Barry Scott (383631), Arvina Ram (4743825), Murray P. Cox (116944), Austen R. D. Ganley (531714), Christopher L. Schardl (383620)   +9 more
core   +1 more source

Impact of Asymptomatic Intracranial Hemorrhage on Outcome After Endovascular Stroke Treatment

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Endovascular treatment (EVT) achieves high rates of recanalization in acute large‐vessel occlusion (LVO) stroke, but functional recovery remains heterogeneous. While symptomatic intracranial hemorrhage (sICH) has been well studied, the prognostic impact of asymptomatic intracranial hemorrhage (aICH) after EVT is less certain ...
Shihai Yang, Chengsong Yue, Zhuang Li, Xiaolei Shi, Haoxuan Zhu, Jie Yang, Linyu Li, Jiaxing Song, Shitao Fan, Gaoming Li, Wenzhe Sun, Zhixian Ye, Jiacheng Huang, Dahong Yang, Jinfu Ma, Xu Xu, Zhixi Wang, Lilan Wang, Guojian Liu, Fengli Li, Changwei Guo, Li Qi, Wenjie Zi   +22 more
wiley   +1 more source

Inferring chromosome radial organization from Hi-C data

BMC Bioinformatics, 2020
Background The nonrandom radial organization of eukaryotic chromosome territories (CTs) inside the nucleus plays an important role in nuclear functional compartmentalization. Increasingly, chromosome conformation capture (Hi-C) based approaches are being
Priyojit Das, Tongye Shen, Rachel Patton McCord   +2 more
doaj   +1 more source

A global high-density chromatin interaction network reveals functional long-range and trans-chromosomal relationships

Genome Biology, 2022
Background Chromatin contacts are essential for gene-expression regulation; however, obtaining a high-resolution genome-wide chromatin contact map is still prohibitively expensive owing to large genome sizes and the quadratic scale of pairwise data ...
Ruchi Lohia, Nathan Fox, Jesse Gillis
doaj   +1 more source