Results 41 to 50 of about 5,385 (167)

Placental Extracellular Vesicles Exhibit Reduced Neurogenic Potential Linked to Changes in Their miRNA Landscape Upon HCMV Infection

Journal of Extracellular Biology, Volume 5, Issue 1, January 2026.
ABSTRACT Extracellular vesicles (EVs) are key mediators of maternal–foetal communication, regulating placental function and foetal development through the transfer of bioactive molecules. Although placental EVs play a crucial role in placental function during pregnancy, their contribution to foetal development, notably foetal brain, remains poorly ...
Charlène Martin, Hélène Martin, Mathilde Bergamelli, Lhorane Lobjois, Lucie Franco, Emma Bordes, Alexandra Benchoua, Stéphanie Balor, Diala Kantar, Etienne Coyaud, Frédéric Martins, Alexandre Favereaux, Cécile E. Malnou   +12 more
wiley   +1 more source

Overall survival post secondary cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for recurrent colorectal cancer with peritoneal metastases

World Journal of Surgical Oncology
Background Colorectal cancer is the third-most common malignancy worldwide. It has the potential to develop peritoneal metastases (CRPM), which can be treated using cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC).
Raymond Hayler, Celine Garrett, Jessica Guo, Shoma Barat, Mina Sarofim, Ruwanthi Wijayawardana, Nima Ahmadi, Winston Liauw, David L. Morris   +8 more
doaj   +1 more source

Meta‐analysis of prognostic factors for patients with colorectal peritoneal metastasis undergoing cytoreductive surgery and heated intraperitoneal chemotherapy

BJS Open, 2019
Background Up to 15 per cent of colorectal cancers present with peritoneal metastases (CPM). Cytoreductive surgery and heated intraperitoneal chemotherapy (CRS + HIPEC) aims to achieve macroscopic tumour resection combined with HIPEC to destroy ...
S. Hallam, R. Tyler, M. Price, A. Beggs, H. Youssef   +4 more
doaj   +1 more source

Hypertherme intraperitoneale chemotherapie (HIPEC)

Huisarts en wetenschap, 2013
Hemmer PHJ, Van Leeuwen BL. Hyperthermic intraperitoneal chemotherapy (HIPEC). Huisarts Wet 2013;56(1):36-9.Surgery forms the basis of cancer therapy, and surgical resection sometimes improves survival in metastatic disease. One such surgical approach is cytoreductive surgery followed by hyperthermic intraperitoneal chemotherapy (HIPEC).
Hemmer, Patrick, Van Leeuwen, Barbara
openaire   +2 more sources

Prospective case‐control cohort analysis of two‐day/two‐stage pelvic exenteration surgery: Safety, feasibility, acceptability and medium‐term outcomes

Colorectal Disease, Volume 28, Issue 1, January 2026.
Abstract Aim Pelvic exenteration (PE) is the only curative option for extensive pelvic cancers. Advances have facilitated increasingly complex resectional and reconstructive components, including per‐operative oncological adjuncts such as intraoperative radiotherapy.
Charles T. West, Yousif Salem, Siddharth Jain, Lewis Matthews, Julian Smith, Marios Nicolaou, Hideaki Yano, Malcolm A. West, Alex H. Mirnezami   +8 more
wiley   +1 more source

Desmoplastic Small Round Cell Tumor of the Abdomen: A Case Report

Case Reports in Pathology, Volume 2026, Issue 1, 2026.
Background Desmoplastic small round cell tumor (DSRCT) is a rare and highly aggressive mesenchymal neoplasm that predominantly arises from the serosal surfaces of the peritoneum, most commonly affecting young males. Due to its rarity, overlapping histologic features with other small round blue cell tumors, and dependence on specialized ...
Ahmed Alsharakhat, Omar Elgamassy, Reema Rajeev, Fatema Kadhem, Carlos Coutinho, Sara George, Suraiya Saleem   +6 more
wiley   +1 more source

HIPEC: The Complexities of Clinical Trials [PDF]

Annals of Surgical Oncology, 2008
The treatment of peritoneal surface malignancies presents unique and challenging problems to the cancer clinician. These patients more than many other cancer patients often suffer from significant and disabling symptoms as a direct result of local tumor progression.
openaire   +2 more sources

Peritoneal Immunosurgery: Immunotherapy Augmented Surgery for the Treatment of Peritoneal Cancers

Journal of Surgical Oncology, Volume 132, Issue 5, Page 789-809, October 2025.
ABSTRACT Peritoneal malignancy often indicates disruptions in multiple physiological systems resulting from widespread cancer. The heterogenous origin and dynamic nature of peritoneal cancer make it difficult to treat with standard approaches that fit into guidelines.
Ada I. Ozcan, Arianexys Aquino López, Mary K. McKenna, Malcolm K. Brenner, Alastair M. Thompson   +4 more
wiley   +1 more source

Risk factors of chronic kidney disease in cisplatin-based hyperthermia intraperitoneal chemotherapy

International Journal of Hyperthermia
Purpose Cisplatin is commonly prescribed in hyperthermic intraperitoneal chemotherapy (HIPEC) for peritoneal malignancy. Acute kidney injury (AKI) is regarded as a common complication after HIPEC combined with cytoreductive surgery (CRS).
Chih-Chung Cheng, Hung-Chieh Yeh, Pei-Wen Su, Chien-Lin Ho, Sheng-Chi Chang   +4 more
doaj   +1 more source

MODERN STRATEGY IN TREATMENT OF PERITONEAL CARCINOMATOSIS

Учёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова, 2017
Peritoneal carcinomatosis (PC) is a common manifestation of progression in peritoneal and gynecologic malignancies. Current primary strategy in treatment of PC is the concept of regional influence by the way of cytoreductive surgery and intraperitoneal ...
A. A. Zakharenko, D. A. Zaitcev, M. A. Belyaev, A. A. Trushin, O. A. Ten, A. S. Natkha, K. N. Vovin, V. A. Rybalchenko   +7 more
doaj   +1 more source