Results 31 to 40 of about 101,099 (274)
Tau Protein and Adult Hippocampal Neurogenesis [PDF]
Frontiers in Neuroscience, 2012 Tau protein is a microtubule-associated protein found in the axonal compartment that stabilizes neuronal microtubules under normal physiological conditions. Tau metabolism has attracted much attention because of its role in neurodegenerative disorders called tauopathies, mainly Alzheimer disease.
Almudena eFuster-Matanzo +9 more
openaire +5 more sources
Adult Neurogenesis and Dendritic Remodeling in Hippocampal Plasticity: Which One is more Important?
Cell Transplantation, 2014 Accumulating knowledge has shown that a decrease in hippocampal neurogenesis is linked to the pathophysiology of mood disorders and some hippocampal-dependent learning and memory tasks.
Suk-Yu Yau, Kwok-Fai So
doaj +1 more source
Frontiers in Neuroscience, 2021 Currently there are approximately 291,000 people suffering from a spinal cord injury (SCI) in the United States. SCI is associated with traumatic changes in mobility and neuralgia, as well as many other long-term chronic health complications, including ...
Arthur Sefiani, Cédric G. Geoffroy
doaj +1 more source
Modulation of Adult Hippocampal Neurogenesis by Sleep: Impact on Mental Health
Frontiers in Neural Circuits, 2017 The process of neurogenesis has been demonstrated to occur throughout life in the subgranular zone (SGZ) of the hippocampal dentate gyrus of several mammals, including humans.
Cristina Navarro-Sanchis +3 more
doaj +1 more source
Chinese Traditional Medicine and Adult Neurogenesis in the Hippocampus
Journal of Traditional and Complementary Medicine, 2014 Adult neurogenesis is an important therapeutic target in treating neurological disorders. Adult neurogenesis takes place in two regions of the brain: Subventricular zone and dentate gyrus in the hippocampus.
Endong Zhang, Jiangang Shen, Kwok Fai So
doaj +1 more source
A new age in understanding adult hippocampal neurogenesis in Alzheimer’s disease
Neural Regeneration Research, 2022 Several lines of evidence have established that proliferation and differentiation of neural stem cells into neurons within the sub-granular zone of the dentate gyrus, a process named adult hippocampal neurogenesis, contribute to maintaining healthy ...
Maya A Hanspal, Sébastien Gillotin
doaj +1 more source
Lithium treatment and human hippocampal neurogenesis [PDF]
Translational Psychiatry, 2021 AbstractLithium is a first-line treatment for bipolar disorder, where it acts as a mood-stabilizing agent. Although its precise mechanism remains unclear, neuroimaging studies have shown that lithium accumulates in the hippocampus and that chronic use amongst bipolar disorder patients is associated with larger hippocampal volumes.
Alish B. Palmos +6 more
openaire +6 more sources
Inflammasome-IL-1β signaling mediates ethanol inhibition of hippocampal neurogenesis
Frontiers in Neuroscience, 2012 Regulation of hippocampal neurogenesis is poorly understood, but appears to contribute to mood and cognition. Ethanol and neuroinflammation are known to reduce neurogenesis. We have found that ethanol induces neuroinflammation supporting the hypothesis
Fulton eCrews
doaj +1 more source
Tet2 Rescues Age-Related Regenerative Decline and Enhances Cognitive Function in the Adult Mouse Brain. [PDF]
, 2018 Restoring adult stem cell function provides an exciting approach for rejuvenating the aging brain. However, molecular mechanisms mediating neurogenic rejuvenation remain elusive.
Bieri, Gregor +6 more
core +2 more sources
Neurotrophins Role in Depression Neurobiology: A Review of Basic and Clinical Evidence [PDF]
, 2011 Depression is a neuropsychiatric disorder affecting a huge percentage of the active population especially in developed countries. Research has devoted much of its attention to this problematic and many drugs have been developed and are currently ...
Berrocoso Domínguez, Esther María +4 more
core +4 more sources