Results 21 to 30 of about 3,003 (174)

Pathogen-reduced plasma, cryoprecipitate reduced for therapeutic plasma exchange. [PDF]

Transfusion
Abstract Background Therapeutic plasma exchange (TPE) for thrombotic thrombocytopenic purpura (TTP) and auto‐immune disorders involves repeated patient exposure to allogenic plasma with the risk of transfusion‐transmitted infection (TTI).
Tupin F, Mouriaux C, Hechler B, Kaastrup K, Yegneswaran S, Corash L, Mangin PH.   +6 more
europepmc   +2 more sources

The effects of a hirudin/liposome complex on a diabetic nephropathy rat model

BMC Complementary and Alternative Medicine, 2019
Background Hirudin, an extract from Hirudo spp., is an anticoagulant used to treat a variety of renal diseases, including diabetic nephropathy (DN).
Hongwu Wang, Huantian Cui, Lan Lin, Yue Ji, Qing Ni, Junchen Li, Jianli Pang, Gongyan Bing, Yuhong Bian   +8 more
doaj   +1 more source

Jalaukāvacaraṇa (Hirudo therapy) in the management of necrosed index finger due to crush injury

Ancient Science of Life, 2018
Necrosis of tissue has become the challenging case, considering the difficulties of its management to bring back the normalcy of dead tissue. Treatment choice in surgery ends up with amputation of the affected part which leads to depression to a patient.
Dudhamal Tukaram Sambhaji, Komang Sudarmi   +1 more
doaj   +1 more source

The Emergency Use of Recombinant Hirudin in Cardiopulmonary Bypass

, 2023
The most common anticoagulant used for cardiopumonary bypass is heparin. An alternate form of anticoagulant therapy is needed for patients who have immune-mediated heparinassociated thrombocytopenia (HIT). Thrombocytopenia causes bleeding and may lead to
Debra S. Douglass, Michael E. Jessen, Nicklett Johnston, Michael DiMaio   +3 more
core   +1 more source

Medicinal leech therapy—an overall perspective

Integrative Medicine Research, 2017
Complementary medicine methods have a long history, but modern medicine has just recently focused on their possible modes of action. Medicinal leech therapy (MLT) or hirudotherapy, an old technique, has been studied by many researchers for possible ...
Ali K. Sig, Mustafa Guney, Aylin Uskudar Guclu, Erkan Ozmen   +3 more
doaj   +1 more source

Ecarin clotting time but not aPTT correlates with PEG-hirudin plasma activity

, 2001
Background: Novel antithrombotic agents such as hirudin have shown promise in the therapy of acute coronary syndromes. PEG-hirudin (polyethyleneglycol conjugated hirudin) has been developed to provide a longer plasma half-life and more stable ...
Nordt, T., Gulba, D.C., Peter, K., Kuebler, W., Bode, C., Ruef, J., Kohler, B., Moser, M., Paterna, N.   +8 more
core   +1 more source

Prognostic Significance of Thrombocytopenia During Hirudin and Heparin Therapy in Acute Coronary Syndrome Without ST Elevation [PDF]

Circulation, 2001
Background —The development of thrombocytopenia in acute coronary syndromes (ACS) appears to be associated with adverse clinical outcomes. Unfractionated heparin is a recognized cause of thrombocytopenia, but the incidence, predictors, and prognostic significance of thrombocytopenia during hirudin therapy in ACS have not been ...
J W, Eikelboom, S S, Anand, S R, Mehta, J I, Weitz, C, Yi, S, Yusuf   +5 more
openaire   +2 more sources

Selective and rapid monitoring of dual platelet inhibition by aspirin and P2Y₁₂ antagonists by using multiple electrode aggregometry

Thrombosis Journal, 2010
Background Poor platelet inhibition by aspirin or clopidogrel has been associated with adverse outcomes in patients with cardiovascular diseases.
Lorenz Reinhard, Tóth Orsolya, Bernlochner Isabell, Penz Sandra M, Calatzis Andreas, Siess Wolfgang   +5 more
doaj   +1 more source

Recombinant Neorudin for the Prevention of Deep-Vein Thrombosis After Spinal-Cord Injury

Drug Design, Development and Therapy, 2023
Yu-Bin Liu,1,2 Yun Liu,1,3 Lin Zhang,1 Xing-Chen Zhou,1 Bo-Yuan Ren,1 Can Zheng,1 Chun-Hua Hao,4 Wei-Ting Wang,4 Xia Xia,5 Gang-Qiao Zhou,1,3 Chu-Tse Wu,1 Ji-De Jin1 1Department of Experimental Hematology and Biochemistry, Beijing Institute of Radiation ...
Liu YB, Liu Y, Zhang L, Zhou XC, Ren BY, Zheng C, Hao CH, Wang WT, Xia X, Zhou GQ, Wu CT, Jin JD   +11 more
doaj  

Reconstructing the Post‐Burn Auricle: A Microsurgical Approach Using a Contralateral Free Temporoparietal Fascial Flap and Autologous Costal Cartilage Framework

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Post‐burn auricular defects compromise both aesthetics and facial symmetry, often imposing significant social and psychological burdens that severely diminish patients' quality of life. Scarring in the mastoid region following burns typically exhibits poor elasticity and texture, along with compromised cutaneous blood supply.
Siming Wei, Yongjun Chen, Liwei Dong
wiley   +1 more source