A comparison of hirudin with heparin in the prevention of restenosis after coronary angioplasty [PDF]
, 1995 __Background:__ The likelihood of restenosis is a major limitation of coronary angioplasty. We studied whether hirudin, a highly selective inhibitor of thrombin with irreversible effects, would prevent restenosis after angioplasty.
Bode, C.H. (Christoph) +11 more
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Hirudotherapy /Leech therapy: Applications and Indications in Surgery
Archives of Clinical and Experimental Surgery, 2012 Hirudotherapy (HT) is the application of medicinal leeches (Hirudo medicinalis) for therapeutic use. It is one of the oldest remedies, being employed by various medicinal practitioners.
Swaid Abdullah +3 more
doaj +1 more source
Anticoagulants for acute ischaemic stroke [PDF]
, 2015 Peer reviewedPublisher ...
Counsell, Carl +2 more
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Drug Design, Development and Therapy, 2020 Background Inflammation-induced podocyte apoptosis plays an important role in kidney injury during diabetic nephropathy (DN). Hirudin (HIR), a natural compound extracted from leeches, can inhibit inflammation. However, whether HIR can protect the kidneys
Jiarui Han +5 more
semanticscholar +1 more source
Jalaukāvacaraṇa (Hirudo therapy) in the management of necrosed index finger due to crush injury
Ancient Science of Life, 2018 Necrosis of tissue has become the challenging case, considering the difficulties of its management to bring back the normalcy of dead tissue. Treatment choice in surgery ends up with amputation of the affected part which leads to depression to a patient.
Dudhamal Tukaram Sambhaji +1 more
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Evaluation of Dr. Szirmai's method of treating thrombosis with neomyograms resp. neomyographs [PDF]
, 1961 Neomyographic examinations were made by the authors on 28 patients. The extent of reconvalescence was measured on the basis of changes in the values recorded by the myograms taken before and after the treatment.
Haberl, A., Juranyi, R.
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Effect of the administration of recombinant hirudin and/or tissue-plasminogen activator (t-PA) on endotoxin-induced disseminated intravascular coagulation model in rabbits [PDF]
, 1999 We evaluated the effect of r-hirudin and/or tissue-plasminogen activator (t-PA) in a model of DIC in rabbits induced by i.v. infusion of 100 micrograms/kg/h/6 h endotoxin. Rabbits were treated with saline (endotoxin control group), r-hirudin at 0.3 mg/kg/
Hermida, J. (José) +5 more
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Argatroban During Percutaneous Transluminal Coronary Angioplasty: Results of a Dose-Verification Study. [PDF]
, 1996 Background. Thrombin is a key enzyme in thrombogenesis. In animals, specific antithrombotic therapy at the time of coronary angioplasty reduced the incidence of subacute occlusion and inhibited the restenosis response.
Gabriel, L. +5 more
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Local (Malaysian) Leech as Alternative Healing Treatment and an Islamic Perspective [PDF]
International Journal of Islamic Thought, 2016 The therapy is known from the time of extreme antiquity, dating back more than 2,500 years ago and still being practiced nowadays. This fact testifies to its efficiency in various health problems.
ZULHISYAM, A. K. +4 more
doaj
Endogenous t-PA release and pharmacological thrombolysis - Experimental animal studies of the coronary circulation [PDF]
, 2006 The physiologically most important activator of intravascular fibrinolysis is tissue-type plasminogen activator (t-PA) released from endothelial cells. In man, sympathomimetic drugs increase the systemic concentration of t-PA. It is therefore of interest
Björkman, Jan-Arne
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