Results 31 to 40 of about 135,178 (348)
Interaction Analysis of a Two-Component System Using Nanodiscs. [PDF]
PLoS ONE, 2016 Two-component systems are the major means by which bacteria couple adaptation to environmental changes. All utilize a phosphorylation cascade from a histidine kinase to a response regulator, and some also employ an accessory protein.
Patrick Hörnschemeyer +4 more
doaj +1 more source
Cyclic di-GMP mediates a histidine kinase/phosphatase switch by noncovalent domain cross-linking [PDF]
, 2016 Histidine kinases are key components of regulatory networks in bacteria. Although many of these enzymes are bifunctional, mediating both phosphorylation and dephosphorylation of downstream targets, the molecular details of this central regulatory switch ...
Dubey, Badri N. +6 more
core +2 more sources
Histidine residue 94 is involved in pH sensing by histidine kinase ArsS of Helicobacter pylori. [PDF]
PLoS ONE, 2009 The ArsRS two-component system is the master regulator of acid adaptation in the human gastric pathogen Helicobacter pylori. Low pH is supposed to trigger the autophosphorylation of the histidine kinase ArsS and the subsequent transfer of the phosphoryl ...
Stefanie Müller +2 more
doaj +1 more source
Nature Communications, 2021 The bacteriophytochrome DrBphP from Deinococcus radiodurans shows high sequence homology to the histidine kinase Agp1 from Agrobacterium fabrum but lacks kinase activity.
Elina Multamäki +12 more
doaj +1 more source
FEBS Open Bio, 2014 Two-component signal transduction systems (TCS), consisting of a sensor histidine protein kinase and its cognate response regulator, are an important mode of environmental sensing in bacteria.
Alisha Dhiman +3 more
doaj +1 more source
Structural and chemical requirements for histidine phosphorylation by the chemotaxis kinase CheA [PDF]
, 2005 The CheA histidine kinase initiates the signal transduction pathway of bacterial chemotaxis by autophosphorylating a conserved histidine on its phosphotransferase domain (P1).
Bilwes, Alexandrine M. +6 more
core +1 more source
NikA/TcsC histidine kinase is involved in conidiation, hyphal morphology, and responses to osmotic stress and antifungal chemicals in Aspergillus fumigatus. [PDF]
PLoS ONE, 2013 The fungal high osmolarity glycerol (HOG) pathway is composed of a two-component system (TCS) and Hog1-type mitogen-activated protein kinase (MAPK) cascade.
Daisuke Hagiwara +7 more
doaj +1 more source
Oligomeric states in sodium ion-dependent regulation of cyanobacterial histidine kinase-2 [PDF]
, 2017 Two-component signal transduction systems (TCSs) consist of sensor histidine kinases and response regulators. TCSs mediate adaptation to environmental changes in bacteria, plants, fungi and protists. Histidine kinase 2 (Hik2) is a sensor histidine kinase
Allen, J +5 more
core +2 more sources
Role of water in the enzymatic catalysis: study of ATP + AMP -> 2ADP conversion by adenylate kinase [PDF]
J. Phys. Chem. A (2010), 2010 The catalytic conversion ATP + AMP -> 2ADP by the enzyme adenylate kinase (ADK) involves the binding of one ATP molecule to the LID domain and one AMP molecule to the NMP domain. The latter is followed by a phosphate transfer, and then the release of two ADP molecules. We have computed a novel two dimensional configurational free energy surface (2DCFES)
arxiv +1 more source
AMB Express, 2018 Helical alignment of the α-helical linker of the LOV (light-oxygen-voltage) domain of YtvA from Bacillus subtilis with the α-helical linker of the histidine-protein kinase domain of the Sln1 kinase of the phospho-relay system for osmoregulation of ...
Aleksandra Bury, Klaas J. Hellingwerf
doaj +1 more source