Results 31 to 40 of about 82,686 (281)

Characterization of CHARK, an unusual cytokinin receptor of rice

Scientific Reports, 2021
The signal transduction of the plant hormone cytokinin is mediated by a His-to-Asp phosphorelay. The canonical cytokinin receptor consists of an extra cytoplasmic hormone binding domain named cyclase/histidine kinase associated sensory extracellular ...
Mhyeddeen Halawa, Anne Cortleven, Thomas Schmülling, Alexander Heyl   +3 more
doaj   +1 more source

Crystallization and initial X-ray diffraction analysis of the multi-domain Brucella blue light-activated histidine kinase LOV-HK in its illuminated state

Biochemistry and Biophysics Reports, 2018
The pathogenic bacterium Brucella abortus codes for a multi-domain dimeric cytoplasmic histidine kinase called LOV-HK, which is a key blue light-activated virulence factor in this microorganism.
Jimena Rinaldi, Ignacio Fernández, Lucía M. Poth, William E. Shepard, Martin Savko, Fernando A. Goldbaum, Sebastián Klinke   +6 more
doaj   +1 more source

Preliminary Study of Resistance Mechanism of Botrytis cinerea to SYAUP-CN-26

Molecules, 2022
SYAUP-CN-26 (1S, 2R-((3-bromophenethyl)amino)-N-(4-chloro-2-trifluoromethylphenyl) cyclohexane-1-sulfonamide) is a novel sulfonamide compound with excellent activity against Botrytis cinerea.
Kai Wang, Huazhong Zhang, Wanying Zhu, Jingnan Peng, Xinghai Li, Yingzi Wang, Zhiqiu Qi   +6 more
doaj   +1 more source

A Unique Sensor Histidine Kinase [PDF]

Journal of Bacteriology, 2009
Sporulation initiation in Bacillus species is controlled by an extended version of two-component signal transduction systems, termed phosphorelay ([4][1]). The cascade of His→Asp→His→Asp phosphotransfer is typically initiated by the ATP-dependent autophosphorylation of the histidine ...
openaire   +2 more sources

Cryo-EM structure of the QseG-QseE complex reveals an accessory protein-driven two-component system activation mechanism

mBio
The two-component system (TCS) enables bacteria to sense and respond to environmental changes through histidine kinase-mediated signaling cascades. Although the core components of TCSs have been extensively studied, the molecular basis of accessory ...
Piqian Gong, Guobang Li, Weixun Li, Mengyuan Xu, Xuyao Jiao, Xudong Chen, Beile Gao, Xiang Gao   +7 more
doaj   +1 more source

A Transmembrane Histidine Kinase Functions as a pH Sensor

Biomolecules, 2020
The two-component system DesK-DesR regulates the synthesis of unsaturated fatty acids in the soil bacteria Bacillus subtilis. This system is activated at low temperature and maintains membrane lipid fluidity upon temperature variations.
Ana Bortolotti, Daniela Belén Vazquez, Juan Cruz Almada, Maria Eugenia Inda, Salvador Iván Drusin, Juan Manuel Villalba, Diego M. Moreno, Jean Marie Ruysschaert, Larisa Estefania Cybulski   +8 more
doaj   +1 more source

Modification of histidine repeat proteins by inorganic polyphosphate

Cell Reports, 2023
Summary: Inorganic polyphosphate (polyP) is a linear polymer of orthophosphate that is present in nearly all organisms studied to date. A remarkable function of polyP involves its attachment to lysine residues via non-enzymatic post-translational ...
Nolan Neville, Kirsten Lehotsky, Zhiyun Yang, Kody A. Klupt, Alix Denoncourt, Michael Downey, Zongchao Jia   +6 more
doaj   +1 more source

Hybrid histidine kinases in pathogenic fungi [PDF]

Molecular Microbiology, 2015
SummaryHistidine kinases (HK) sense and transduce via phosphorylation events many intra‐ and extracellular signals in bacteria, archaea, slime moulds and plants. HK are also widespread in the fungal kingdom, but their precise roles in the regulation of physiological processes remain largely obscure.
Defosse, Tatiana, Sharma, Anupam, Mondal, Alok, Dugé de Bernonville, Thomas, Latgé, Jean-Paul, Calderone, Richard, Giglioli-Guivarc'H, Nathalie, Courdavault, Vincent, Clastre, Marc, Papon, Nicolas   +9 more
openaire   +3 more sources

Identification of possible Ser/Thr/Tyr phosphorylation sites in the fungal histidine kinase CaNik1p by peptide array technique

Bulletin of Faculty of Pharmacy Cairo University, 2018
CaNik1p is a histidine kinase (HK) that is present in Candida albicans. It was found to be a target for antifungal activities on the hyperosmotic glycerol pathway.
Mohammed El-Mowafy, Ursula Bilitewski
doaj   +1 more source

Proteolysis and multimerization regulate signaling along the two-component regulatory system AdeRS

iScience, 2021
Summary: Bacterial two-component regulatory systems are ubiquitous environment-sensing signal transducers involved in pathogenesis and antibiotic resistance.
Zhenlin Ouyang, Fang Zheng, Li Zhu, Jan Felix, Di Wu, Ke Wu, Irina Gutsche, Yi Wu, Peter M. Hwang, Junjun She, Yurong Wen   +10 more
doaj   +1 more source