Results 11 to 20 of about 211,982 (321)

Paul I. Terasaki, Ph.D: a pioneer in transplant medicine and a dedicated philanthropist [PDF]

open access: yesFrontiers in Transplantation
In the last five decades, remarkable surgical and medical advances ensued within the field of organ transplantation. These strides were marked by significant breakthroughs in transplant immunology, with Dr. Paul I.
Jon Kobashigawa
doaj   +2 more sources

Selective Deletion of HLA-B, and -C Class I Genes Promotes Immunocompatibility of Humanized Skin Graft Model [PDF]

open access: yesImmunoTargets and Therapy
Laura Cobos-Figueroa,1,2,* Laura Notario,1,* Carmen Mir,1 Carlos Molpeceres,2 Sara Lauzurica,2 Daniel López,1 Elena Lorente,1,* Pilar Lauzurica1,* 1Centro Nacional de Microbiología, Insituto de Salud Carlos III, Majadahonda, Madrid, Spain;
Cobos-Figueroa L   +7 more
doaj   +2 more sources

Pretransplant histocompatibility testing algorithm: Laboratory and clinical approach in the Indian context

open access: yesIndian Journal of Transplantation, 2021
Remarkable advances in histocompatibility testing have immensely improved the safety of transplantation and have decreased the incidence of rejections.
Feroz Aziz   +3 more
doaj   +1 more source

Transplanting the Elderly: Mandatory Age- and Minimal Histocompatibility Matching

open access: yesFrontiers in Immunology, 2020
Worldwide over 40% of patients receiving renal replacement therapy (RRT) are aged 65 years or older, a number that is still increasing. Renal transplantation is the preferred RRT, providing substantial survival benefit over those remaining on dialysis ...
Geertje J. Dreyer, Johan W. de Fijter
doaj   +1 more source

Qualitative and quantitative comparison of cell-free DNA and cell-free fetal DNA isolation by four (semi-)automated extraction methods: impact in two clinical applications: chimerism quantification and noninvasive prenatal diagnosis

open access: yesJournal of Translational Medicine, 2021
Background Non-invasive molecular analysis of cell-free DNA (cfDNA) became a sensitive biomarker for monitoring organ transplantation or for detection of fetal DNA (cffDNA) in noninvasive prenatal test. In this study, we compared the efficiencies of four
Pascal Pedini   +9 more
doaj   +1 more source

Biocompatibility of polyetheretherketone for the treatment of orbital bone defects [PDF]

open access: yesInternational Journal of Ophthalmology, 2020
AIM: To investigate the biocompatibility and therapeutic effects of polyetheretherketone (PEEK) on recovery of a rabbit orbital defect. METHODS: Totally 16 New Zealand rabbits were used to establish an orbital bone defect model and then randomly divided
Rui-Dong Gu   +4 more
doaj   +1 more source

Clinical, immunological and ethical aspects of selecting a recipient for cadaver kidney transplantation

open access: yesВестник трансплантологии и искусственных органов, 2020
The decision to choose a particular patient for kidney transplantation is made through two consecutive decisions: decision to include the patient on the waiting list and decision to select a patient competitively among several candidates for transplant ...
V. A. Vatazin   +2 more
doaj   +1 more source

Clinical heterogeneity in a family with flail arm syndrome and review of hnRNPA1‐related spectrum

open access: yesAnnals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1910-1917, December 2022., 2022
Abstract Objective Flail arm syndrome (FAS) is one of the atypical subtypes of amyotrophic lateral sclerosis (ALS). Mutations in hnRNPA1 encoding heterogeneous nuclear ribonucleoprotein (hnRNP) A1 are a rare genetic cause of ALS. Herein, marked clinical heterogeneity of FAS in a pedigree with a known hnRNPA1 variant was described to raise early ...
Xiaochen Han   +5 more
wiley   +1 more source

The Accuracy of Sequence-Specific Oligonucleotide and Real-Time Polymerase Chain Reaction HLA Typing in Determining the Presence of Pre-Transplant Donor-Specific Anti-HLA Antibodies and Total Eplet Mismatches for Deceased Donor Kidney Transplantation

open access: yesFrontiers in Immunology, 2022
High resolution human leukocyte antigen (HLA) typing is important in establishing eplet compatibility and the specificity of donor-specific anti-HLA antibodies (DSA).
Nicholas G. Larkins   +14 more
doaj   +1 more source

Highly Sensitized Patients Are Well Served by Receiving a Compatible Organ Offer Based on Acceptable Mismatches

open access: yesFrontiers in Immunology, 2021
Highly sensitized kidney patients accrue on the transplant waiting list due to their broad immunization against non-self Human Leucocyte Antigens (HLA).
Sebastiaan Heidt   +3 more
doaj   +1 more source

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