Results 21 to 30 of about 617,156 (199)
Epigenetic Alterations in Human Papillomavirus-Associated Cancers
Viruses, 2017 Approximately 15–20% of human cancers are caused by viruses, including human papillomaviruses (HPVs). Viruses are obligatory intracellular parasites and encode proteins that reprogram the regulatory networks governing host cellular signaling pathways ...
David Soto +2 more
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Dermatologica Sinica, 2023 Primary cutaneous mucinous carcinoma (PCMC) is rare, and its carcinogenesis is unclear. Trimethylation of histone H3 at lysine 27 (H3K27me3) is a key regulator in chromatin remodeling-controlled transcription.
Shu-Hao Li +2 more
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Pathogens, 2012 EBNA1, a nuclear protein expressed in all EBV-associated neoplasms is indispensable for the maintenance of the viral episomes in latently infected cells.
Hans Helmut Niller, Janos Minarovits
doaj +1 more source
Epigenetic Regulation of Autophagy: A Path to the Control of Autoimmunity
Frontiers in Immunology, 2018 Autoimmune diseases are a significant cause of debilitation and mortality globally and are in need of cost-effective therapeutics. Autophagy is a cellular pathway that facilitates immune modulation involved in both pathogen control and autoimmunity ...
Jessica C. Hargarten +1 more
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Frontiers in Pharmacology, 2017 Introduction: Epigenetic regulation of fibrogenesis through post-translational histone modifications (marks) may be a key determinant of progression in renal disease. In this study, we examined the distribution and acquisition of histone 3 Lysine 9 (H3K9)
Timothy D. Hewitson +8 more
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Frontiers in Cardiovascular Medicine, 2022 BackgroundPatients successfully resuscitated from cardiac arrest often develop organ dysfunction caused by systemic inflammation and increased coagulation, leading to disseminated intravascular coagulation (DIC).
Asumi Mizugaki +4 more
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Journal of Applied Botany and Food Quality, 2013 Flavanols as a small subclass of the flavonoids stain selectively blue with the special reagent p-dimethylaminocinnamaldehyde (DMACA). Because of the prominent blue colour it is easy to recognize the flavanols histochemically in the vacuoles of expanding
Jürgen Polster +4 more
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New Insights in Transcriptional Regulation of the Ethylene Response in Arabidopsis
Frontiers in Plant Science, 2019 As any living organisms, plants must respond to a wide variety of environmental stimuli. Plant hormones regulate almost all aspects of plant growth and development.
Likai Wang +3 more
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A short guide to histone deacetylases including recent progress on class II enzymes
Experimental and Molecular Medicine, 2020 The interaction between histones and DNA is important for eukaryotic gene expression. A loose interaction caused, for example, by the neutralization of a positive charge on the histone surface by acetylation, induces a less compact chromatin structure ...
Suk-Youl Park, Jeong-Sun Kim
semanticscholar +1 more source
Pharmacological Inhibition of LSD1 for Cancer Treatment
Molecules, 2018 Lysine-specific demethylase 1A (LSD1, also named KDM1A) is a demethylase that can remove methyl groups from histones H3K4me1/2 and H3K9me1/2. It is aberrantly expressed in many cancers, where it impedes differentiation and contributes to cancer cell ...
Guan-Jun Yang +4 more
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