Results 191 to 200 of about 115,732 (260)

Contribution of reversible histone acetylation to freeze tolerance and recovery in wood frog kidneys. [PDF]

Sci Rep
Taiwo OO, Storey KB.
europepmc   +1 more source

BRD9 inhibition as potential treatment option for testicular germ cell tumors

Andrology, EarlyView.
Abstract Background Testicular germ cell tumors (TGCT) are the predominant tumor in younger males. Usually, 5‐year survival rates are quite high, but 15–20% of patients with metastatic non‐seminomas are resistant to standard cisplatin‐based therapy.
Aylin Hansen, Christine Sanders, Florian Fronhoffs, Kai Funke, Glen Kristiansen, Hubert Schorle   +5 more
wiley   +1 more source

Unraveling the role of histone acetylation in sepsis biomarker discovery. [PDF]

Front Mol Biosci
Cheng F, Deng J, Du Z, Li L, Qiu Z, Zhu M, Zhao H, Wang Z.   +7 more
europepmc   +1 more source

Impact of Chemotherapy on Sperm Functional Characteristics in Patients With Testicular Germ Cell Tumours

Andrology, EarlyView.
ABSTRACT Background Testicular germ cell tumours (TGCT) are the most common malignancies among young men and represent a major threat to reproductive health. Both the disease itself and oncological treatments, particularly chemotherapy, can compromise spermatogenesis and semen quality.
Ondrej Sanovec, Ondrej Simonik, Zuzana Kratka, Lukas Ded, Jana Vondrakova, Maryam Qasemi, Barbora Bryndova, Michala Krejci, Daniela Spevakova, Vishma Pratap Sur, Radomir Kren, Tomas Hradec, Pavel Skrobanek, Ludmila Boublikova, Libor Zamecnik, Tomas Buchler, Jiri Neuzil, Pavla Postlerova, Katerina Komrskova   +18 more
wiley   +1 more source

Histone acetylation readers Bdf1 and Yaf9 direct SWR1 remodeler to +1 nucleosome. [PDF]

Sci Adv
Ranjan A, Elalaoui E, Tang X, Cha J, Louder RK, Nguyen K, Ye J, Bennani M, Gardner AM, Liu D, Pugh BF, Wu C.   +11 more
europepmc   +1 more source

[Histone acetylation].

Postepy biochemii, 1986
openaire   +1 more source

The Functional Role and Molecular Characterization of the Therapeutic Target CLDN6 in Germ Cell Tumors

Andrology, EarlyView.
ABSTRACT Background The tight junction protein CLDN6 has been identified as a cancer‐associated cell surface marker that is rarely expressed in healthy tissues. In testicular germ cell tumors (GCT), CLDN6 is particularly detectable in seminomas, embryonal carcinomas, and choriocarcinomas.
Jule Zwick, Margaretha A. Skowron, Gereon Poschmann, Patrick Petzsch, Ann Kathrin Bergmann, Kai Stühler, Jochen Hecht, Daniel Nettersheim   +7 more
wiley   +1 more source

Butyrate blocks specific histone acetylation by preventing recruitment of p300 to acetylated histones

Jiang M, Psoma A, Lyu J, Chiariello MG, Modderman R, Bianchi F, Incarnato D, Marrink S, Jonkers IH, van den Bogaart G.   +9 more
europepmc   +1 more source

Reversion of aortic valve cells calcification by activation of Notch signalling via histone acetylation induction. [PDF]

Signal Transduct Target Ther
Garoffolo G, Ferrari S, De Martino S, Pizzo E, Candino V, Curini L, Macrì F, Kruithof BPT, Mongelli A, Grillo M, Fanotti N, Fejzaj P, Casaburo M, Alanazi A, Marsan NA, Khaliel F, Alsulbud A, Agrifoglio M, Colombo GI, Chiesa M, Farsetti A, Gaetano C, Raucci A, Pesce M.   +23 more
europepmc   +1 more source

Chromodomain Helicase DNA–Binding Proteins and Spermatogenesis: Current Advances

Andrology, EarlyView.
ABSTRACT Background Male infertility is a prevalent clinical condition, with approximately one‐third of cases classified as idiopathic, frequently stemming from impaired spermatogenesis because of dysregulated gene expression. Chromodomain helicase DNA‐binding (CHD) proteins are central chromatin remodelers that orchestrate this epigenetic regulation ...
Mingrui Zhang, Di Liu, Guoqiang Liu, Minggang Zhu, Feng Pan   +4 more
wiley   +1 more source