Results 201 to 210 of about 189,363 (327)

Chemically Modified Histone H3 to Study Acetylation at the Nucleosome Dyad

, 2009
Mridula Manohar
openalex   +1 more source

Hyperinsulinemia promotes aberrant histone acetylation in triple-negative breast cancer [PDF]

, 2019
Parijat Senapati, Hiroyuki Kato, Michael Lee, Amy Leung, Christine Thai, Angelica Sanchez, Emily J. Gallagher, Derek LeRoith, Victoria L. Seewaldt, David K. Ann, Dustin E. Schones   +10 more
openalex   +1 more source

Inherited metabolic epilepsies–established diseases, new approaches

Epilepsia Open, EarlyView.
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

Epigenetic Factors in Pathogenesis of Retinoblastoma: DNA Methylation and Histone Acetylation. [PDF]

Curr Issues Mol Biol
Kiosis G, Skourtsidis K, Ioannou D, Tseriotis VS, Stergiou K, Akritidou F, Papamitsou T, Kourti M, Karachrysafi S.   +8 more
europepmc   +1 more source

EGR1 Nuclear Condensates Promote Renal Cyst Development in Polycystic Kidney Disease

Exploration, EarlyView.
ABSTRACT Autosomal dominant polycystic kidney disease (ADPKD) is marked by aberrant cell proliferation driven by cAMP‐PKA and MAPK signaling pathways. EGR1, a transcription factor directly activated by the above two pathways, is critical in the over‐proliferation of tumor cells, which share similarities with cystic epithelial cells in ADPKD. This study
Chaoqun Ren, Zhaoxu Wu, Min Li, Yaqin Du, Hong Zhou, Yazhu Quan, Mengyao Xiong, Yiming Wang, Zhiwei Qiu, Shuai Zhu, Xiaowei Li, Jinzhao He, Cai Gao, Hui Cai, Tingting Li, Baoxue Yang   +15 more
wiley   +1 more source

Influences of DNA Methylation and Histone Acetylation on Gene Expressions

Yu Wang
openalex   +2 more sources

Histone acetylation of the htr3a gene in the prefrontal cortex of Wistar rats regulates ethanol-seeking behavior.

, 2012
Yahui Xu, Xuebing Liu, Xiaojie Zhang, Guanbai Zhang, Ruiling Zhang, Tieqiao Liu, Wei Hao   +6 more
openalex   +1 more source

The BRD4-nucleosome interaction is enhanced modestly and non-selectively by histone acetylation. [PDF]

Nucleic Acids Res
Lambrechts LS, Reid XJ, Kambanis L, Luong C, Kobakhidze E, Daners A, Zhong Y, Patel K, Franck CK, Sani HM, Taylor C, Low JKK, Payne RJ, Mackay JP.   +13 more
europepmc   +1 more source

Roles of histone chaperone Nap1 and histone acetylation in regulating phase-separation of nucleosome arrays. [PDF]

Nat Commun
Gao J, Li H, Tan S, Zhou R, Lee TH.
europepmc   +1 more source

Somatic cell reprogramming for Parkinson's disease treatment

Ibrain, Volume 11, Issue 1, Page 59-73, Spring 2025.
The fundamental purpose of cell reprogramming to treat Parkinson's disease is to generate dopaminergic neurons (DAN) and do transplantation. There are two ways to accomplish this. One method is to induce cells into induced DA neurons (iDAN) directly or to induce cells into induced pluripotent stem cells and ultimately into iDAN in vitro. Another option
Xiaozhuo Li, Kevin Fang, Fengping Wang
wiley   +1 more source