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Surrogate Alcohols and Their Metabolites Modify Histone H3 Acetylation: Involvement of Histone Acetyl Transferase and Histone Deacetylase

Alcoholism: Clinical and Experimental Research, 2008
Background:  Ethanol increases histone H3 acetylation in the rat liver. However, the effect of other carbon chain length alcohols, consumed as surrogate alcohols and used in industry, on H3 acetylation is unknown. Hence, we investigated the effect of these alcohols on histone H3 acetylation, cell toxicity and HAT and HDAC activity.Methods:  Primary ...
Mahua, Choudhury, Shivendra D, Shukla
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Plant histone acetylation: In the beginning…

Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 2011
The study of histone acetylation in plants started with protein purification and sequencing, with gel analysis and the use of radioactive tracers. In alfalfa, acid urea Triton gel electrophoresis and in vivo labeling with tritated acetate and lysine quantified dynamic acetylation of core histones and identified the replication-coupled and -independent ...
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Histone acetylation and an epigenetic code

BioEssays, 2000
The enzyme-catalyzed acetylation of the N-terminal tail domains of core histones provides a rich potential source of epigenetic information. This may be used both to mediate transient changes in transcription, through modification of promoter-proximal nucleosomes, and for the longer-term maintenance and modulation of patterns of gene expression.
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Histone acetylation: facts and questions

Chromosoma, 1994
The DNA of eukaryotic cells is organized in a complex with proteins, either as interphase chromatin or mitotic chromosomes. Nucleosomes, the structural subunits of chromatin, have long been considered as static structures, incompatible with processes occurring in chromatin.
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Modulation of cellular processes by histone and non-histone protein acetylation

Nature Reviews Molecular Cell Biology, 2022
Asifa Akhtar   +2 more
exaly  

Histone acetylation dynamics regulating plant development and stress responses

Cellular and Molecular Life Sciences, 2021
Jitendra Kumar Thakur   +2 more
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Histone acetylation sets Pol II

Nature Reviews Molecular Cell Biology, 2014
Zlotorynski Eytan, Eytan Zlotorynski
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Functions and mechanisms of non-histone protein acetylation

Nature Reviews Molecular Cell Biology, 2018
Takeo Narita   +2 more
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