Results 111 to 120 of about 223,415 (361)

A Role of Histone Acetylation in the Regulation of Circadian Rhythm in Ants

iScience, 2020
Summary: In many organisms, circadian rhythms and associated oscillations in gene expression are controlled by post-translational modifications of histone proteins.
Romain Libbrecht, Dennis Nadrau, Susanne Foitzik   +2 more
doaj   +1 more source

The physics of epigenetics

, 2016
In higher organisms, all cells share the same genome, but every cell expresses only a limited and specific set of genes that defines the cell type. During cell division, not only the genome, but also the cell type is inherited by the daughter cells. This
Barbi, Maria, Caré, Bertrand R., Cortini, Ruggero, Lavelle, Christophe, Lesne, Annick, Mozziconacci, Julien, Victor, Jean-Marc   +6 more
core   +3 more sources

Histone deacetylases and their roles in mineralized tissue regeneration

Bone Reports, 2017
Histone acetylation is an important epigenetic mechanism that controls expression of certain genes. It includes non-sequence-based changes of chromosomal regional structure that can alter the expression of genes.
Nam Cong-Nhat Huynh, Vincent Everts, Ruchanee Salingcarnboriboon Ampornaramveth   +2 more
doaj   +1 more source

Somatic cell reprogramming for Parkinson's disease treatment

Ibrain, Volume 11, Issue 1, Page 59-73, Spring 2025.
The fundamental purpose of cell reprogramming to treat Parkinson's disease is to generate dopaminergic neurons (DAN) and do transplantation. There are two ways to accomplish this. One method is to induce cells into induced DA neurons (iDAN) directly or to induce cells into induced pluripotent stem cells and ultimately into iDAN in vitro. Another option
Xiaozhuo Li, Kevin Fang, Fengping Wang
wiley   +1 more source

Histone acetyltransferase PfGCN5 regulates stress responsive and artemisinin resistance related genes in Plasmodium falciparum [PDF]

, 2021
Mukul Rawat, Abhishek Kanyal, Aishwarya Sahasrabudhe, Shruthi Sridhar Vembar, José-Juan Lopez-Rubio, Krishanpal Karmodiya   +5 more
openalex   +1 more source

Mechanisms of spinal glial activation in chemotherapy‐induced peripheral neuropathy: Focus on microglia and astrocytes

Ibrain, EarlyView.
Chemotherapy‐induced peripheral neuropathy (CIPN) remains a major clinical challenge, with central sensitization considered an important pathological mechanism in its occurrence and persistence. This review focuses on spinal astrocytes and microglia, systematically summarizing the pathological mechanisms of spinal glial cells involved in CIPN caused by
Long Gu, Song Cao, Yonghuai Feng
wiley   +1 more source

RNA Binding to CBP Stimulates Histone Acetylation and Transcription [PDF]

, 2017
CBP/p300 are transcription co-activators whose binding is a signature of enhancers, cis-regulatory elements that control patterns of gene expression in multicellular organisms. Active enhancers produce bi-directional enhancer RNAs (eRNAs) and display CBP/
Bailey, Barlev, Bedford, Beltran, Berndsen, Bezzi, Bonasio, Bowers, Castello, Cifuentes-Rojas, Corcoran, Creyghton, Daniel A. Bose, Danny Reinberg, Davidovich, De Santa, Delvecchio, Di Ruscio, Friedersdorf, Greg Donahue, Gupta, Hafner, Hah, He, Heinz, Hendrickson, Henry, Hilton, Hsieh, Huang, Huppertz, Jin, Kagey, Kaikkonen, Kaneko, Kaneko, Kaneko, Kasper, Kim, Kim, Lai, Lam, Lam, Langmead, Li, Li, Lienert, Liu, Lowary, Luger, Martin, Matys, May, Melo, Meng, Mousavi, Peterson, Pnueli, Postepska-Igielska, Quinlan, Rada-Iglesias, Ramin Shiekhattar, Roberto Bonasio, Schaukowitch, Schröder, Shelley L. Berger, Shen, Stasevich, Sun, Tanaka, Thompson, Thompson, Tie, Wang, Wang, Wang, Wang, Wang, Wongtrakoongate, Yang, Yue, Zhang, Ørom   +82 more
core   +1 more source

Epigenetic Regulation in the Pathogenesis of Renal Inflammation: Insights and Therapeutic Potentials

iNew Medicine, EarlyView.
ABSTRACT Renal inflammation is a common pathological process in various kidney diseases, often initiated by factors such as toxins, ischemia, or autoimmune reactions. This inflammatory response can result in structural damage and a rapid decline in renal function.
Yu‐Hang Dong, Xiao‐Yu Shen, Han‐Cheng Jin, Xiang‐Yu Li, Hao He, Xiao‐Ming Meng   +5 more
wiley   +1 more source

Purifi cation of Multiprotein Histone Acetyltransferase Complexes [PDF]

, 2011
The reversible acetylation of specific lysine residues on core histones regulates gene transcription in eukaryotes. Since the discovery of GCN5 as the first transcription-regulating histone acetyltransferase (HAT), a variety of HATs have now been identified and shown to acetylate different sites on histones as well as on non-histone proteins, including
Yuan-Liang, Wang, Francesco, Faiola, Ernest, Martinez   +2 more
openaire   +2 more sources

Organoids and organ‐on‐a‐chip models for investigating the pathophysiology of the human reproductive system

Interdisciplinary Medicine, EarlyView.
Organoids and organ‐on‐a‐chips are advancing reproductive system research. In the female reproductive system, applications include cancer organoid models, placental chips, and hormone simulation models. For the male reproductive system, research focuses on drug resistance mechanisms, co‐culture platforms, and infertility studies. These refined in vitro
Hongqi Zhang, Shiwen Deng, Fangfang Jin, Jiayao Qu, Xiang Fan, Peng Chen, Xinrong Fan   +6 more
wiley   +1 more source