Results 191 to 200 of about 102,004 (245)

Allergic Sensitization to Inhalant Allergens in the Upper Respiratory Tract—the B Cell Side

Allergy, EarlyView.
ABSTRACT Allergic diseases are on the rise worldwide, driven by respiratory epithelial barrier dysfunction that promotes sensitization to inhalant allergens such as pollen, dust mites, pet dander, and fungal spores. These antigens trigger IgE‐mediated immune responses that lead to diseases such as allergic rhinitis (AR) and asthma.
Ola Grimsholm, Mohammed Zghaebi, Bita Hambrecht, Tanja Kalic, Christopher C. Udoye, Rudolf Manz, Barbara Bohle, Katarzyna M. Sitnik, Julia Eckl‐Dorna, Heimo Breiteneder   +9 more
wiley   +1 more source

Inhibition of histone deacetylase 3 in dental mesenchyme regulates the development of tooth root. [PDF]

J Bone Miner Res
Niibe K, Begun DL, Doi-Fujimura K, Nagasaki A, Zars E, Li X, Taylor EL, MacDougall MB, Egusa H, Westendorf JJ.   +9 more
europepmc   +1 more source

Histone deacetylase (HDAC) [PDF]

Science-Business eXchange, 2010
openaire   +1 more source

Identification of MEF2A, MEF2C, and MEF2D interactomes in basal and Fsk‐stimulated mouse MA‐10 Leydig cells

Andrology, EarlyView.
Abstract Background Myocyte enhancer factor 2 transcription factors regulate essential transcriptional programs in various cell types. The activity of myocyte enhancer factor 2 factors is modulated through interactions with cofactors, chromatin remodelers, and other regulatory proteins, which are dependent on cell context and physiological state.
Karine de Mattos, Marie‐Pier Scott‐Boyer, Arnaud Droit, Robert S. Viger, Jacques J. Tremblay   +4 more
wiley   +1 more source

Novel selective indole based histone deacetylase 10 inhibitors as anticancer therapeutics. [PDF]

Sci Rep
Tarawneh AH, Al-Trawneh SA, Yesiloglu TZ, Zessin M, Robaa D, Barinka C, Schutkowski M, Sippl W, Ross SA.   +8 more
europepmc   +1 more source

Clonal haematopoiesis in T‐follicular helper cell lymphoma: A prognostic biomarker and early event in lymphoma evolution

British Journal of Haematology, EarlyView.
Summary T‐follicular helper cell lymphomas (TFHLs) are frequently associated with epigenetic mutations and clonal haematopoiesis (CH), but the clinical and prognostic implications of CH in TFHL remains unclear. We performed next‐generation sequencing on paired peripheral blood (PB) and tumour tissue samples from 30 patients with TFHL. CH was defined by
Chong Wei, Yan Zhang, Danqing Zhao, Wei Zhang, Daobin Zhou   +4 more
wiley   +1 more source

Histone deacetylase 6 inhibits STING-dependent antiviral immunity via site-specific deacetylation. [PDF]

J Biol Chem
Qu M, Wei D, Ke Q, Cheng P, Ma Y, Afera B, Guo K, Li M, Yin X, Wang X, Han J, Sun Y.   +11 more
europepmc   +1 more source

Mycosis fungoides and Sézary syndrome

British Journal of Haematology, EarlyView.
Summary Mycosis fungoides (MF) and Sézary syndrome (SS) are the most common cutaneous T‐cell lymphomas, arising from mature CD4+ memory T cells. Diagnosis is complex and relies on clinicopathological correlation, immunophenotyping and molecular clonality testing, while management is stage‐adapted, with potentially curative outcomes achievable only in ...
Francisco Martins, Joana Calvão
wiley   +1 more source

Comprehensive Structure-Activity Relationship Analysis of Benzamide Derivatives as Histone Deacetylase 1 (HDAC1) Inhibitors. [PDF]

Int J Mol Sci
Soto-Delgado J, Rodríguez-Núñez YA, Guerra C, Prent-Peñaloza L, Bacho M.   +4 more
europepmc   +1 more source