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DNA Methylation Dictates Histone H3K4 Methylation [PDF]
Molecular and Cellular Biology, 2007 Histone lysine methylation and DNA methylation contribute to transcriptional regulation. We have previously shown that acetylated histones are associated with unmethylated DNA and are nearly absent from the methylated DNA regions by using patch-methylated stable episomes in human cells.
Cindy Yen, Okitsu, Chih-Lin, Hsieh
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G3: Genes, Genomes, Genetics, 2016 Histone methylation levels, which are determined by the action of both histone demethylases and methyltransferases, impact multiple biological processes by affecting gene expression activity.
Mengying Liu +2 more
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DNA methylation underpins the epigenomic landscape regulating genome transcription in Arabidopsis
Genome Biology, 2022 Background It is challenging to determine the effect of DNA methylation on the epigenetic landscape and the function in higher organisms due to the lack of DNA methylation-free mutants.
Lun Zhao +6 more
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Methylated DNMT1 and E2F1 Are Targeted for Proteolysis by L3MBTL3 and CRL4DCAF5 Ubiquitin Ligase [PDF]
, 2018 Many non-histone proteins are lysine methylated and a novel function of this modification is to trigger the proteolysis of methylated proteins. Here, we report that the methylated lysine 142 of DNMT1, a major DNA methyltransferase that preserves ...
Alejo, Salvador +7 more
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BMC Plant Biology, 2010 Background Modifications of DNA and histones in various combinations are correlated with many cellular processes. In this study, we investigated the possible relationship between histone H4 tetraacetylation, DNA methylation and histone H3 dimethylation ...
Yang Fei +7 more
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Mimicking Methylated Histones [PDF]
ACS Chemical Biology, 2007 Histones with specific patterns of lysine methylation help to define how their associated DNA is used. A recent semisynthetic strategy for generating histone proteins that contain methyl-lysine analogues at specific sites will provide researchers with the materials to further elucidate the role of these modifications.
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Redox Biology, 2021 Preterm birth is still a major health problem and maternal inflammation has been shown to play a role. The combination of maternal inflammation and neonatal hyperoxia contributes to epigenetic changes that influence gene expression and the development of
Sophia S. Sugar +4 more
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SUVH1, a Su(var)3-9 family member, promotes the expression of genes targeted by DNA methylation. [PDF]
, 2015 Transposable elements are found throughout the genomes of all organisms. Repressive marks such as DNA methylation and histone H3 lysine 9 (H3K9) methylation silence these elements and maintain genome integrity.
Chen, Xuemei +6 more
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Controlling histone methylation via trans-histone pathways [PDF]
Epigenetics, 2008 Covalent post-translational modifications of histones have been demonstrated to participate in a wide array of cellular processes, including regulation of gene transcription, gene repression, DNA double strand break repair and mitosis. Regulation of how these covalent modifications, and the implications of this regulation, are currently of great ...
Ian M, Fingerman +2 more
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Research progress on histone acetylation/methylation in oral diseases [PDF]
口腔疾病防治Histone acetylation and methylation can affect chromatin conformation and regulate a variety of biological activities. Abnormal histone acetylation and methylation modifications are related to the occurrence and development of a variety of oral diseases.
LUO Yuchuan, LI Feifei, YU Fanyuan, YIN Bei, YE Ling
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