Results 41 to 50 of about 257,789 (305)
BMC Genomics, 2019 Background During decidualization in endometrial stromal cells (ESCs), expressions of a number of genes and epigenetic modifications of histones are altered.
Ryo Maekawa +8 more
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Trithorax group proteins: switching genes on and keeping them active [PDF]
, 2011 Cellular memory is provided by two counteracting groups of chromatin proteins termed Trithorax group (TrxG) and Polycomb group (PcG) proteins. TrxG proteins activate transcription and are perhaps best known because of the involvement of the TrxG protein ...
Cavalli, G. +3 more
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Global lysine methylome profiling using systematically characterized affinity reagents
Scientific Reports, 2023 Lysine methylation modulates the function of histone and non-histone proteins, and the enzymes that add or remove lysine methylation—lysine methyltransferases (KMTs) and lysine demethylases (KDMs), respectively—are frequently mutated and dysregulated in ...
Christine A. Berryhill +7 more
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Epigenomes in Cardiovascular Disease. [PDF]
, 2018 If unifying principles could be revealed for how the same genome encodes different eukaryotic cells and for how genetic variability and environmental input are integrated to impact cardiovascular health, grand challenges in basic cell biology and ...
McKinsey TA +4 more
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Histone Deimination Antagonizes Arginine Methylation [PDF]
Cell, 2004 Methylation of arginine residues within histone H3 has been linked to active transcription. This modification appears on the estrogen-regulated pS2 promoter when the CARM1 methyltransferase is recruited during transcriptional activation. Here we describe a process, deimination, that converts histone arginine to citrulline and antagonizes arginine ...
Cuthbert, Graeme L. +10 more
openaire +2 more sources
Relationship between histone demethylase LSD family and development and prognosis of gastric cancer
Frontiers in Immunology, 2023 Objectiveto elucidate the correlation between histone demethylase and gastric cancerResearch objecthistone demethylase and gastric cancerResultsAs one of the important regulatory mechanisms in molecular biology and epigenetics, histone modification plays
Liyan Dong +8 more
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Journal of Diabetes Research, 2017 Aims. Latent autoimmune diabetes in adults (LADA) is an autoimmune disease of which the mechanism is not clear. Emerging evidence suggests that histone methylation contributes to autoimmunity. Methods.
Xi-yu Liu, Hong Li
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Вавиловский журнал генетики и селекции, 2016 Epigenetic modifications are studied intensively to understand mechanisms of long-term memory. We have shown that histone H3 methylation is important for the defense reflexes formation in the mollusk Helix lucorum.
L. N. Grinkevich, O. V. Vorobiova
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Arabidopsis homologs of retinoblastoma-associated protein 46/48 associate with a histone deacetylase to act redundantly in chromatin silencing. [PDF]
PLoS Genetics, 2011 RNA molecules such as small-interfering RNAs (siRNAs) and antisense RNAs (asRNAs) trigger chromatin silencing of target loci. In the model plant Arabidopsis, RNA-triggered chromatin silencing involves repressive histone modifications such as histone ...
Xiaofeng Gu +5 more
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Specific binding of the methyl binding domain protein 2 at the BRCA1-NBR2 locus [PDF]
, 1996 The methyl-CpG binding domain (MBD) proteins are key molecules in the interpretation of DNA methylation signals leading to gene silencing. We investigated their binding specificity at the constitutively methylated region of a CpG island containing the ...
Auriol, Emilie +3 more
core +2 more sources