Results 31 to 40 of about 166,151 (260)
Epigenetic modifications are studied intensively to understand mechanisms of long-term memory. We have shown that histone H3 methylation is important for the defense reflexes formation in the mollusk Helix lucorum.
L. N. Grinkevich, O. V. Vorobiova
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DNA Methylation Dictates Histone H3K4 Methylation [PDF]
Histone lysine methylation and DNA methylation contribute to transcriptional regulation. We have previously shown that acetylated histones are associated with unmethylated DNA and are nearly absent from the methylated DNA regions by using patch-methylated stable episomes in human cells.
Cindy Yen, Okitsu, Chih-Lin, Hsieh
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Background Epigenetic modifications, including CG methylation (a major form of DNA methylation) and histone modifications, interact with each other to shape their genomic distribution patterns.
Wan Kin Au Yeung +2 more
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Molecular Coupling of DNA Methylation and Histone Methylation [PDF]
The combinatorial pattern of DNA and histone modifications constitutes an epigenetic 'code' that shapes gene-expression patterns by enabling or restricting the transcriptional potential of genomic domains. DNA methylation is associated with histone modifications, particularly the absence of histone H3 lysine 4 methylation (H3K4me0) and the presence of ...
Hideharu, Hashimoto +2 more
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Raf1 Is a DCAF for the Rik1 DDB1-like protein and has separable roles in siRNA generation and chromatin modification. [PDF]
Non-coding transcription can trigger histone post-translational modifications forming specialized chromatin. In fission yeast, heterochromatin formation requires RNAi and the histone H3K9 methyltransferase complex CLRC, composed of Clr4, Raf1, Raf2, Cul4,
Alessia Buscaino +10 more
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Relationship between histone demethylase LSD family and development and prognosis of gastric cancer
Objectiveto elucidate the correlation between histone demethylase and gastric cancerResearch objecthistone demethylase and gastric cancerResultsAs one of the important regulatory mechanisms in molecular biology and epigenetics, histone modification plays
Liyan Dong +8 more
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Aims. Latent autoimmune diabetes in adults (LADA) is an autoimmune disease of which the mechanism is not clear. Emerging evidence suggests that histone methylation contributes to autoimmunity. Methods.
Xi-yu Liu, Hong Li
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Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
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Arabidopsis homologs of retinoblastoma-associated protein 46/48 associate with a histone deacetylase to act redundantly in chromatin silencing. [PDF]
RNA molecules such as small-interfering RNAs (siRNAs) and antisense RNAs (asRNAs) trigger chromatin silencing of target loci. In the model plant Arabidopsis, RNA-triggered chromatin silencing involves repressive histone modifications such as histone ...
Xiaofeng Gu +5 more
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Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
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