Results 31 to 40 of about 166,151 (260)

Opposite roles of serotonin and neuropeptide FMRFamide in the regulation of epigenetic processes involved in the longterm memory formation

open access: yesВавиловский журнал генетики и селекции, 2016
Epigenetic modifications are studied intensively to understand mechanisms of long-term memory. We have shown that histone H3 methylation is important for the defense reflexes formation in the mollusk Helix lucorum.
L. N. Grinkevich, O. V. Vorobiova
doaj   +1 more source

DNA Methylation Dictates Histone H3K4 Methylation [PDF]

open access: yesMolecular and Cellular Biology, 2007
Histone lysine methylation and DNA methylation contribute to transcriptional regulation. We have previously shown that acetylated histones are associated with unmethylated DNA and are nearly absent from the methylated DNA regions by using patch-methylated stable episomes in human cells.
Cindy Yen, Okitsu, Chih-Lin, Hsieh
openaire   +2 more sources

A convolutional neural network-based regression model to infer the epigenetic crosstalk responsible for CG methylation patterns

open access: yesBMC Bioinformatics, 2021
Background Epigenetic modifications, including CG methylation (a major form of DNA methylation) and histone modifications, interact with each other to shape their genomic distribution patterns.
Wan Kin Au Yeung   +2 more
doaj   +1 more source

Molecular Coupling of DNA Methylation and Histone Methylation [PDF]

open access: yesEpigenomics, 2010
The combinatorial pattern of DNA and histone modifications constitutes an epigenetic 'code' that shapes gene-expression patterns by enabling or restricting the transcriptional potential of genomic domains. DNA methylation is associated with histone modifications, particularly the absence of histone H3 lysine 4 methylation (H3K4me0) and the presence of ...
Hideharu, Hashimoto   +2 more
openaire   +2 more sources

Raf1 Is a DCAF for the Rik1 DDB1-like protein and has separable roles in siRNA generation and chromatin modification. [PDF]

open access: yesPLoS Genetics, 2012
Non-coding transcription can trigger histone post-translational modifications forming specialized chromatin. In fission yeast, heterochromatin formation requires RNAi and the histone H3K9 methyltransferase complex CLRC, composed of Clr4, Raf1, Raf2, Cul4,
Alessia Buscaino   +10 more
doaj   +1 more source

Relationship between histone demethylase LSD family and development and prognosis of gastric cancer

open access: yesFrontiers in Immunology, 2023
Objectiveto elucidate the correlation between histone demethylase and gastric cancerResearch objecthistone demethylase and gastric cancerResultsAs one of the important regulatory mechanisms in molecular biology and epigenetics, histone modification plays
Liyan Dong   +8 more
doaj   +1 more source

Reduced Histone H3 Lysine 9 Methylation Contributes to the Pathogenesis of Latent Autoimmune Diabetes in Adults via Regulation of SUV39H2 and KDM4C

open access: yesJournal of Diabetes Research, 2017
Aims. Latent autoimmune diabetes in adults (LADA) is an autoimmune disease of which the mechanism is not clear. Emerging evidence suggests that histone methylation contributes to autoimmunity. Methods.
Xi-yu Liu, Hong Li
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Arabidopsis homologs of retinoblastoma-associated protein 46/48 associate with a histone deacetylase to act redundantly in chromatin silencing. [PDF]

open access: yesPLoS Genetics, 2011
RNA molecules such as small-interfering RNAs (siRNAs) and antisense RNAs (asRNAs) trigger chromatin silencing of target loci. In the model plant Arabidopsis, RNA-triggered chromatin silencing involves repressive histone modifications such as histone ...
Xiaofeng Gu   +5 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

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