Histone modifications and their role in epigenetics of atopy and allergic diseases
Allergy, Asthma & Clinical Immunology, 2018 This review covers basic aspects of histone modification and the role of posttranslational histone modifications in the development of allergic diseases, including the immune mechanisms underlying this development.
Bilal Alaskhar Alhamwe +11 more
doaj +1 more source
Predicting gene expression in the human malaria parasite Plasmodium falciparum using histone modification, nucleosome positioning, and 3D localization features. [PDF]
, 2019 Empirical evidence suggests that the malaria parasite Plasmodium falciparum employs a broad range of mechanisms to regulate gene transcription throughout the organism's complex life cycle.
Cook, Kate +4 more
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Histone Modifications as an Intersection Between Diet and Longevity
Frontiers in Genetics, 2019 Histone modifications are key epigenetic regulators that control chromatin structure and gene transcription, thereby impacting on various important cellular phenotypes.
Diego Molina-Serrano +4 more
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Chromatin status and transcription factor binding to gonadotropin promoters in gonadotrope cell lines. [PDF]
, 2017 BackgroundProper expression of key reproductive hormones from gonadotrope cells of the pituitary is required for pubertal onset and reproduction. To further our understanding of the molecular events taking place during embryonic development, leading to ...
Brayman, Melissa J +6 more
core +3 more sources
Domain Model Explains Propagation Dynamics and Stability of Histone H3K27 and H3K36 Methylation Landscapes [PDF]
, 2020 Chromatin states must be maintained during cell proliferation to uphold cellular identity and genome integrity. Inheritance of histone modifications is central in this process. However, the histone modification landscape is challenged by incorporation of
Alabert +58 more
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Epigenetics, 2023 Histones are subjected to extensive covalent modifications that affect inter-nucleosomal interactions as well as alter chromatin structure and DNA accessibility.
Yang Yu +4 more
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BPA-Induced Deregulation of Epigenetic Patterns: Effects on Female Zebrafish Reproduction [PDF]
, 2016 Bisphenol A (BPA) is one of the commonest Endocrine Disruptor Compounds worldwide. It interferes with vertebrate reproduction, possibly by inducing deregulation of epigenetic mechanisms.
Carnevali, Oliana +6 more
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Readers of histone modifications [PDF]
Cell Research, 2011 Histone modifications not only play important roles in regulating chromatin structure and nuclear processes but also can be passed to daughter cells as epigenetic marks. Accumulating evidence suggests that the key function of histone modifications is to signal for recruitment or activity of downstream effectors. Here, we discuss the latest discovery of
Miyong, Yun +3 more
openaire +2 more sources
Site selective reading of epigenetic markers by a dual-mode synthetic receptor array. [PDF]
, 2017 Variably functionalized self-folding deep cavitands form an arrayed, fluorescent indicator displacement assay system for the detection of post-translationally modified (PTM) histone peptides.
Bardeen, Christopher J +8 more
core +2 more sources
PTMViz: a tool for analyzing and visualizing histone post translational modification data
BMC Bioinformatics, 2021 Background Histone post-translational modifications (PTMs) play an important role in our system by regulating the structure of chromatin and therefore contribute to the regulation of gene and protein expression. Irregularities in histone PTMs can lead to
Kevin Chappell +6 more
doaj +1 more source