Results 31 to 40 of about 2,172,961 (295)

The inheritance of histone modifications depends upon the location in the chromosome in Saccharomyces cerevisiae. [PDF]

PLoS ONE, 2011
Histone modifications are important epigenetic features of chromatin that must be replicated faithfully. However, the molecular mechanisms required to duplicate and maintain histone modification patterns in chromatin remain to be determined.
Hiroshi Masumoto, Ryuichiro Nakato, Masato Kanemaki, Katsuhiko Shirahige, Mayumi Hachinohe   +4 more
doaj   +1 more source

GoPeaks: histone modification peak calling for CUT&Tag

Genome Biology, 2022
Genome-wide mapping of histone modifications is critical to understanding transcriptional regulation. CUT&Tag is a new method for profiling histone modifications, offering improved sensitivity and decreased cost compared with ChIP-seq.
William M. Yashar, Garth Kong, Jake VanCampen, Brittany M. Curtiss, Daniel J. Coleman, Lucia Carbone, Galip Gürkan Yardimci, Julia E. Maxson, Theodore P. Braun   +8 more
doaj   +1 more source

Combinatorial Pattern of Histone Modifications in Exon Skipping Event

Frontiers in Genetics, 2019
Histone modifications are associated with alternative splicing. It has been suggested that histone modifications act in combinational patterns in gene expression regulation.
Wei Chen, Wei Chen, Wei Chen, Xiaoming Song, Hao Lin   +4 more
doaj   +1 more source

Arabidopsis thaliana: a powerful model organism to explore histone modifications and their upstream regulations

Epigenetics, 2023
Histones are subjected to extensive covalent modifications that affect inter-nucleosomal interactions as well as alter chromatin structure and DNA accessibility.
Yang Yu, Sihan Wang, Ziqin Wang, Renwei Gao, Joohyun Lee   +4 more
doaj   +1 more source

SnapShot: Histone Modifications

Cell, 2014
Histone proteins are decorated by a variety of protein posttranslational modifications called histone marks that modulate chromatin structure and function, contributing to the cellular gene expression program. This SnapShot summarizes the reported human, mouse, and rat histone marks, including recently identified lysine acylation marks.
Huang, He, Sabari, Benjamin R., Garcia, Benjamin A., Allis, C. David, Zhao, Yingming   +4 more
openaire   +2 more sources

Assessing the in vitro Binding Specificity of Histone Modification Reader Proteins Using Histone Peptide Arrays

Bio-Protocol, 2021
In the field of chromatin biology, a major goal of understanding the roles of histone post-translational modifications is to identify the proteins and domains that recognize these modifications.
Mark Soo, Arneet Saltzman
doaj   +1 more source

Histone ubiquitination and deubiquitination in transcription, DNA damage response, and cancer

Frontiers in Oncology, 2012
Histone post-transcriptional modifications play essential roles in regulation of all DNA related processes. Among them, histone ubiquitination has been discovered for more than three decades.
Jian eCao, Qin eYan
doaj   +1 more source

PTMViz: a tool for analyzing and visualizing histone post translational modification data

BMC Bioinformatics, 2021
Background Histone post-translational modifications (PTMs) play an important role in our system by regulating the structure of chromatin and therefore contribute to the regulation of gene and protein expression. Irregularities in histone PTMs can lead to
Kevin Chappell, Stefan Graw, Charity L. Washam, Aaron J. Storey, Chris Bolden, Eric C. Peterson, Stephanie D. Byrum   +6 more
doaj   +1 more source

Histone modification in Drosophila [PDF]

Briefings in Functional Genomics, 2012
Post-translational modifications (PTMs) of nucleosomal core histones play roles in basic biological processes via altering chromatin structure and creating target sites for proteins acting on chromatin. Several features make Drosophila a uniquely effective model for studying PTMs.
openaire   +2 more sources

Hi–C interaction graph analysis reveals the impact of histone modifications in chromatin shape

Applied Network Science, 2021
Chromosome conformation capture experiments such as Hi–C map the three-dimensional spatial organization of genomes in a genome-wide scale. Even though Hi–C interactions are not biased towards any of the histone modifications, previous analysis has ...
Emre Sefer
doaj   +1 more source