Results 11 to 20 of about 2,172,961 (295)

Epigenetic regulation of histone modifications in glioblastoma: recent advances and therapeutic insights [PDF]

Biomarker Research
Glioblastoma (GBM) is the most common primary malignant brain tumor, characterized by its aggressive behavior, limited treatment options, and poor prognosis. Despite advances in surgery, radiotherapy, and chemotherapy, the median survival of GBM patients
Li Zhang, Yang Yang, Yanchu Li, Chenyu Wang, Chenbin Bian, Hongbin Wang, Feng Wang   +6 more
doaj   +2 more sources

The interplay of histone modifications – writers that read

EMBO Reports, 2015
Histones are subject to a vast array of posttranslational modifications including acetylation, methylation, phosphorylation, and ubiquitylation.
Tianyi Zhang, Sarah Cooper, Neil Brockdorff   +2 more
exaly   +2 more sources

Regulation of chromatin by histone modifications

Cell Research, 2011
Andrew J Bannister, Tony Kouzarides, Bannister Andrew J   +2 more
exaly   +2 more sources

Histone modifications in the regulation of erythropoiesis. [PDF]

Ann Med
The pathogenesis of anemia and other erythroid dysphasia are mains poorly understood, primarily due to limited knowledge about the differentiation processes and regulatory mechanisms governing erythropoiesis. Erythropoiesis is a highly complex and precise biological process, that can be categorized into three distinct stages: early erythropoiesis ...
Wu X, Xu H, Xia E, Gao L, Hou Y, Sun L, Zhang H, Cheng Y.   +7 more
europepmc   +4 more sources

Editorial: Histone modifications in cancer [PDF]

Frontiers in Pharmacology
Jiaqian Luo, Sizhi P. Gao
doaj   +2 more sources

Histone modifications in neurodifferentiation of embryonic stem cells

Heliyon, 2022
Post-translational modifications of histone proteins regulate a long cascade of downstream cellular activities, including transcription and replication.
Min Huang, Xiaoxiao Xiao, Guanxu Ji, Qiang Wu   +3 more
doaj   +1 more source

Single-cell CUT&Tag profiles histone modifications and transcription factors in complex tissues

Nature Biotechnology, 2021
In contrast to single-cell approaches for measuring gene expression and DNA accessibility, single-cell methods for analyzing histone modifications are limited by low sensitivity and throughput.
Marek Bartošovič, Mukund Kabbe, G. Castelo-Branco   +2 more
semanticscholar   +1 more source

Histones and histone modifications [PDF]

Current Biology, 2004
Histone variants, distinct patterns of posttranslational modifications of histones, and histone tail binding proteins all contribute to establishment of various ‘open’ or ‘closed’ chromatin domains that have specialized folding properties and biological functions. Some of these domains can be propagated through DNA replication and mitosis, guaranteeing
Peterson, Craig L, Laniel, Marc-André
openaire   +2 more sources

Histone variants shape chromatin states in Arabidopsis

eLife, 2023
How different intrinsic sequence variations and regulatory modifications of histones combine in nucleosomes remain unclear. To test the importance of histone variants in the organization of chromatin we investigated how histone variants and histone ...
Bhagyshree Jamge, Zdravko J Lorković, Elin Axelsson, Akihisa Osakabe, Vikas Shukla, Ramesh Yelagandula, Svetlana Akimcheva, Annika Luisa Kuehn, Frédéric Berger   +8 more
doaj   +1 more source

Histone Modifications and Non-Coding RNAs: Mutual Epigenetic Regulation and Role in Pathogenesis

International Journal of Molecular Sciences, 2022
In the last few years, more and more scientists have suggested and confirmed that epigenetic regulators are tightly connected and form a comprehensive network of regulatory pathways and feedback loops.
I. Bure, M. Nemtsova, E. Kuznetsova
semanticscholar   +1 more source