Results 21 to 30 of about 198,744 (258)
Histone Modifications as an Intersection Between Diet and Longevity
Frontiers in Genetics, 2019 Histone modifications are key epigenetic regulators that control chromatin structure and gene transcription, thereby impacting on various important cellular phenotypes.
Diego Molina-Serrano +4 more
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Epigenetics, 2023 Histones are subjected to extensive covalent modifications that affect inter-nucleosomal interactions as well as alter chromatin structure and DNA accessibility.
Yang Yu +4 more
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Histone ubiquitination and deubiquitination in transcription, DNA damage response, and cancer
Frontiers in Oncology, 2012 Histone post-transcriptional modifications play essential roles in regulation of all DNA related processes. Among them, histone ubiquitination has been discovered for more than three decades.
Jian eCao, Qin eYan
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PTMViz: a tool for analyzing and visualizing histone post translational modification data
BMC Bioinformatics, 2021 Background Histone post-translational modifications (PTMs) play an important role in our system by regulating the structure of chromatin and therefore contribute to the regulation of gene and protein expression. Irregularities in histone PTMs can lead to
Kevin Chappell +6 more
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Bio-Protocol, 2021 In the field of chromatin biology, a major goal of understanding the roles of histone post-translational modifications is to identify the proteins and domains that recognize these modifications.
Mark Soo, Arneet Saltzman
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Histone modification in Drosophila [PDF]
Briefings in Functional Genomics, 2012 Post-translational modifications (PTMs) of nucleosomal core histones play roles in basic biological processes via altering chromatin structure and creating target sites for proteins acting on chromatin. Several features make Drosophila a uniquely effective model for studying PTMs.
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Hi–C interaction graph analysis reveals the impact of histone modifications in chromatin shape
Applied Network Science, 2021 Chromosome conformation capture experiments such as Hi–C map the three-dimensional spatial organization of genomes in a genome-wide scale. Even though Hi–C interactions are not biased towards any of the histone modifications, previous analysis has ...
Emre Sefer
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Classification of Promoters Based on the Combination of Core Promoter Elements Exhibits Different Histone Modification Patterns. [PDF]
PLoS ONE, 2016 Four different histones (H2A, H2B, H3, and H4; two subunits each) constitute a histone octamer, around which DNA wraps to form histone-DNA complexes called nucleosomes.
Yayoi Natsume-Kitatani +1 more
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SnapShot: Histone Modifications
Cell, 2014 Histone proteins are decorated by a variety of protein posttranslational modifications called histone marks that modulate chromatin structure and function, contributing to the cellular gene expression program. This SnapShot summarizes the reported human, mouse, and rat histone marks, including recently identified lysine acylation marks.
Huang, He +4 more
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Histones and histone modifications in protozoan parasites
Cellular Microbiology, 2006 Protozoan parasites are early branching eukaryotes causing significant morbidity and mortality in humans and livestock. Single-celled parasites have evolved complex life cycles, which may involve multiple host organisms, and strategies to evade host immune responses.
William J, Sullivan +2 more
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