Results 51 to 60 of about 2,005,250 (367)

VEZF1 elements mediate protection from DNA methylation [PDF]

, 2010
There is growing consensus that genome organization and long-range gene regulation involves partitioning of the genome into domains of distinct epigenetic chromatin states.
AC Bell, Adam G. West, AG West, AG West, AG West, Alan Hair, CD Lewis, CL Li, D Macleod, F Antequera, F Recillas-Targa, Gary Felsenfeld, H Gowher, Humaira Gowher, IG Lin, J Aitsebaomo, J Stalder, JA Wallace, Jacqueline Dickson, JH Chung, JH Chung, JP Issa, KS Wendt, L Valenzuela, Lisa Stubbs, M Brandeis, M Gaszner, M Marin, M Oki, MC Barton, Miklos Gaszner, MJ Pikaart, MM Suzuki, MN Prioleau, MN Prioleau, MS Turker, N Koyano-Nakagawa, PA Jones, PB Talbert, PD Jackson, PE Szabo, R Buckle, R Jaenisch, R Kellum, R Straussman, Ruslan Strogantsev, S Fan, S Huang, S Huang, S Yao, SP Clark, T Hashimshony, V Mutskov, VJ Mutskov, VK Rakyan   +54 more
core   +5 more sources

Role of enhancer of zeste homolog 2 polycomb protein and its significance in tumor progression and cell differentiation [PDF]

, 2013
Epigenetics is a branch of genetics that focuses on the heritable changes of DNA or associated proteins, other than DNA sequence variations, which carry information content during cell division [1,2].
Bagella, Luigi Marco, Marchesi, Irene
core   +2 more sources

Coordinated effects of sequence variation on DNA binding, chromatin structure, and transcription. [PDF]

, 2013
DNA sequence variation has been associated with quantitative changes in molecular phenotypes such as gene expression, but its impact on chromatin states is poorly characterized.
Bielser, D., Bryois, J., Core, L.J., Deplancke, B., Dermitzakis, E.T., Gschwind, A.R., Gutierrez-Arcelus, M., Hacker, D., Hernandez, N., Kilpinen, H., Lappalainen, T., Lis, J.T., Migliavacca, E., Orioli, A., Padioleau, I., Panousis, N.I., Planchon, A., Raghav, S.K., Reymond, A., Romano-Palumbo, L., Thurnheer, S., Udin, G., Waszak, S.M., Wiederkehr, M., Witwicki, R.M., Yurovsky, A.   +25 more
core   +1 more source

Resetting histone modifications during human parental-to-zygotic transition

Science, 2019
Epigenetics of human embryonic development Substantial epigenetic reprogramming occurs in mammalian early development. Xia et al. investigated the reprogramming dynamics of three key histone modifications in human early embryonic development.
Weikun Xia, Jiawei Xu, Guang Yu, G. Yao, Kai Xu, Xueshan Ma, N. Zhang, Bofeng Liu, Tong Li, Zili Lin, Xia Chen, Lijia Li, Qiujun Wang, Dayuan Shi, S. Shi, Yile Zhang, Wenyan Song, Haixia Jin, Linli Hu, Z. Bu, Yang Wang, Jie Na, Wei Xie, Ying-pu Sun   +23 more
semanticscholar   +1 more source

Extracting histones for the specific purpose of label-free MS [PDF]

, 2016
Extracting histones from cells is the first step in studies that aim to characterize histones and their post-translational modifications (hPTMs) with MS.
De Clerck, Laura, Deforce, Dieter, Dhaenens, Maarten, Govaert, Elisabeth, Meert, Paulien, Scheerlinck, Ellen, Stella, Martina, Van Steendam, Katleen, Vossaert, Liesbeth, Willems, Sander   +9 more
core   +2 more sources

Crossing epigenetic frontiers: the intersection of novel histone modifications and diseases

Signal Transduction and Targeted Therapy
Histone post-translational modifications (HPTMs), as one of the core mechanisms of epigenetic regulation, are garnering increasing attention due to their close association with the onset and progression of diseases and their potential as targeted ...
Weiyi Yao, Xinting Hu, Xin Wang
semanticscholar   +1 more source

N6-methyladenosine RNA modification regulates embryonic neural stem cell self-renewal through histone modifications

Nature Neuroscience, 2018
Internal N6-methyladenosine (m6A) modification is widespread in messenger RNAs (mRNAs) and is catalyzed by heterodimers of methyltransferase-like protein 3 (Mettl3) and Mettl14.
Yang Wang, Yue Li, Minghui Yue, Jun Wang, Sandeep Kumar, R. Wechsler-Reya, Zhaolei Zhang, Y. Ogawa, Manolis Kellis, G. Duester, Jing Crystal Zhao   +10 more
semanticscholar   +1 more source

Preserving genome integrity and function: the DNA damage response and histone modifications

Critical reviews in biochemistry and molecular biology, 2019
Modulation of chromatin templates in response to cellular cues, including DNA damage, relies heavily on the post-translation modification of histones.
Jae Jin Kim, S. Lee, K. Miller
semanticscholar   +1 more source

DeepDiff: DEEP‐learning for predicting DIFFerential gene expression from histone modifications [PDF]

Bioinform., 2018
Motivation Computational methods that predict differential gene expression from histone modification signals are highly desirable for understanding how histone modifications control the functional heterogeneity of cells through influencing differential ...
Arshdeep Sekhon, Ritambhara Singh, Yanjun Qi   +2 more
semanticscholar   +1 more source

ChIP-seq profiling of H3K4me3 and H3K27me3 in an invasive insect, Bactroceradorsalis

Frontiers in Genetics, 2023
Introduction: While it has been suggested that histone modifications can facilitate animal responses to rapidly changing environments, few studies have profiled whole-genome histone modification patterns in invasive species, leaving the regulatory ...
Yan Zhao, Juntao Hu, Jiajiao Wu, Zhihong Li   +3 more
doaj   +1 more source