Results 111 to 120 of about 66,203 (260)
HIV-1 Transcription and Latency in the Spotlight
VirusesAt every integrated HIV-1 genome, there is a transcriptional cycle that ultimately shapes proviral fate [...]
openaire +3 more sources
Bevacizumab‐Associated Eczema Herpeticum in Metastatic Ovarian Carcinoma: A Case Report
JEADV Clinical Practice, EarlyView.ABSTRACT Eczema herpeticum (EH) is a rare but potentially life‐threatening cutaneous infection caused by herpes simplex virus (HSV), classically associated with atopic dermatitis. Its occurrence in oncology patients receiving anti‐angiogenic targeted therapy and cytotoxic chemotherapy is exceedingly uncommon.
Mandeep Dutta Joshi +6 more
wiley +1 more source
Scientific Reports, 2017 A potential strategy to cure HIV-1 infection is to use latency reversing agents (LRAs) to eliminate latent reservoirs established in resting CD4+ T (rCD4+) cells.
María Rosa López-Huertas +7 more
doaj +1 more source
Movement Disorders Clinical Practice, EarlyView.ABSTRACT Background Classifying abnormal tongue movements is challenging due to their varied presentations and limited visibility compared to other body parts. Accurate identification of the phenomenology guides physical examination and can point to specific diagnoses.
Nathaniel Bendahan +4 more
wiley +1 more source
Schematic of the HIV-1 latency circuit.
, 2018 The events associated with HIV-1 transcription and translation that govern the latency of an HIV-1 infected cell are depicted as a set of reactions (see Eqs (1)–(18) in Methods).
Narendra M. Dixit (135562) +1 more
core +1 more source
Plasmepsins as Antimalarial Drug Targets—Then, Now, and the Future
Medicinal Research Reviews, EarlyView.ABSTRACT Malaria is a devastating disease caused by Plasmodium parasites. Plasmodium parasites express ten cathepsin D‐like aspartyl proteases, called plasmepsins (PMs). These PMs have diverse roles fulfill diverse functions throughout the parasite's lifecycle, though several exhibit functional redundancies. Among them, PMV, PMIV, and PMX are essential
Brad E. Sleebs
wiley +1 more source
CBP/p300 lysine acetyltransferases inhibit HIV-1 expression in latently infected T cells
iScienceSummary: HIV-1 latency is regulated by chromatin modifying enzymes, and histone deacetylase inhibitors (HDACi) cause reactivation of provirus expression.
Riley M. Horvath, Ivan Sadowski
doaj +1 more source
The UK register of HIV seroconverters: Methods and analytical issues
, 1996 A Register of HIV-infected persons who have had a negative antibody test within 3 years of their first antibody positive test (seroconverters) is being set up in the UK to monitor the distribution of times from HIV seroconversion to AIDS (the incubation ...
Babiker, A +18 more
core
Epigenetic Regulation of HIV-1 Latency by Cytosine Methylation
PLoS Pathogens, 2009 Human immunodeficiency virus type 1 (HIV-1) persists in a latent state within resting CD4+ T cells of infected persons treated with highly active antiretroviral therapy (HAART). This reservoir must be eliminated for the clearance of infection. Using a cDNA library screen, we have identified methyl-CpG binding domain protein 2 (MBD2) as a regulator of ...
Kauder, Steven E +4 more
openaire +6 more sources
Nanjing Consensus II on Washed Microbiota Transplantation: Statements From the CHINAGUT Conference
Microbiota Medicine Research, EarlyView.ABSTRACT The new method of fecal microbiota transplantation, based on automatic facilities and washing processes, was coined as washed microbiota transplantation (WMT). The first recommendations on WMT were released as Nanjing Consensus report by the fecal microbiota transplantation (FMT)‐standardization Study Group in 2019.
Faming Zhang +53 more
wiley +1 more source