Results 111 to 120 of about 30,551,261 (265)

Correlates of HIV-1 genital shedding in Tanzanian women. [PDF]

, 2011
BACKGROUND: Understanding the correlates of HIV shedding is important to inform strategies to reduce HIV infectiousness. We examined correlates of genital HIV-1 RNA in women who were seropositive for both herpes simplex virus (HSV)-2 and HIV-1 and who ...
Clare Tanton, David A. Ross, Watson-Jones Deborah, Weiss, Helen A, Watson-Jones, Deborah, Helen A Weiss, Richard J. Hayes, Laurent Belec, Tanton, Clare, Le Goff, Jerome, Hayes, Richard J, Deborah Watson-Jones, Le Goff Jerome, Belec Laurent, Baisley, Kathy, Changalucha John, Weiss Helen A., Everett Dean, Ross, David A, Everett, Dean, David A Ross, Kathy Baisley, Changalucha, John, Mary Rusizoka, Jerome Le Goff, Helen A. Weiss, John Changalucha, Tanton Clare, Dean Everett, Richard J Hayes, Baisley Kathy, Ross David A., Rusizoka, Mary, Rusizoka Mary, Hayes Richard J., Belec, Laurent   +35 more
core   +1 more source

Advancing Therapies for Mycobacterial Diseases: From Small Molecules to Host‐Directed Strategies

Medicinal Research Reviews, EarlyView.
ABSTRACT The global burden of multidrug‐resistant tuberculosis (MDR‐TB) and the rising incidence of nontuberculous mycobacterial (NTM) infections highlight the urgent need for innovative therapeutic strategies. Current treatments are prolonged, toxic, and increasingly compromised by resistance and limited diagnostic capacity.
Tânia Silva, Alessandra Aiello, Tonino Alonzi, M. Alice Carvalho, Vladimir Finger, Delia Goletti, Sven Hoffner, Yousra Kherabi, Jan Korabecny, Julia Kulczyńska, Agnieszka Kyzioł, Alicia Lacoma, Filomena Martins, Zorica Nanovic, Sepideh Hosseiniporgham, Martina Hrast Rambaher, Leonardo Antonio Sechi, Daria Smalchuk, Grażyna Stochel, Lydia Tabernero, Nancy L. Tateosian, Violeta Valcheva, Anamarija Zega, Mafalda Sarraguça   +23 more
wiley   +1 more source

The role of miR-29a in HIV-1 replication and latency

Journal of Virus Eradication, 2017
The development of an effective HIV-1 eradication strategy relies upon a clear understanding of the cellular mechanisms involved in HIV-1 latency. Among such cellular processes, microRNA activities affect HIV-1 production by regulating viral transcripts as well as host cell HIV-1 dependency factors. miR-29a stands apart from other relevant microRNAs as
Frattari, Giacomo, Aagaard, Lars; id_orcid 0000-0002-2896-0439, Denton, Paul W   +2 more
openaire   +4 more sources

Cost-effectiveness of voluntary HIV-1 counseling and testing in reducing sexual transmission of HIV-1 in Kenya and Tanzania. [PDF]

, 2000
Background Access to HIV-1 voluntary counseling and testing (VCT) is severely limited in less-developed countries. We undertook a multisite trial of HIV-1 VCT to assess its impact, cost, and cost-effectiveness in less-developed country settings.\ud ...
Sangiwa , G, Balmer, D, Sweat , M, Furlonge , C, Coates , T, Kamenga , C, Gregorich , S, Grinstead, O   +7 more
core  

An Evaluation on the Role of Non-Coding RNA in HIV Transcription and Latency: A Review

, 2023
Peter W Ramirez,1 Christina Pantoja,1 Nadejda Beliakova-Bethell2,3 1Department of Biological Sciences, California State University, Long Beach, CA, USA; 2VA San Diego Healthcare System and Veterans Medical Research Foundation, San Diego, CA, USA ...
Pantoja C, Beliakova-Bethell N, Ramirez PW   +2 more
core  

Business‐Like Narrative and Public Engagement: Evidence From TED Talks on Nonprofit Issues

Nonprofit Management and Leadership, EarlyView.
ABSTRACT While the trend of nonprofits adopting business‐like practices has been widely discussed, limited attention has been paid to how the broader public responds to this shift. One way to capture public reactions is by examining engagement with business‐like narratives in media.
Jun Zhang
wiley   +1 more source

Gene silencing in HIV-1 latency by polycomb repressive group [PDF]

, 2011
Background The persistence of latently Human immunodeficiency virus-1 (HIV-1) infected cellular reservoirs in resting CD4+ T cells is a major obstacle to HIV-1 eradication. The detailed mechanism of HIV-1 latency remains unclear. We investigated histones
Choi, SY, Kyung-Chang Kim, Hyeon Kim, Sung Soon Kim, Sang-Yun Choi, Kim, KC, Roh, TY, Kim, HG, Park Jihwan, Choi, BS, Hyeon Guk Kim, Kim Sung, Kim Kyung-Chang, Sung Kim, Jihwan Park, Jung Kyung-Min, Choi Byeong-Sun, Tae-Young Roh, Kyung-Min Jung, Choi Sang-Yun, Byeong-Sun Choi, Kim, SS, Lee Joo-Shil, Roh Tae-Young, Kim Hyeon, Park, J, Joo-Shil Lee, Jung, KM, Lee, JS   +28 more
core   +1 more source

Sickle Cell Disease: Historical Overview and Current Therapies

Prenatal Diagnosis, EarlyView.
ABSTRACT Sickle cell disease (SCD) affects millions worldwide, yet the limited treatment options currently available do not always adequately control the disease and carry significant side effects. At present, the only curative treatment is hematopoietic stem cell (HSC) transplantation, a procedure that carries considerable challenges and numerous ...
Oluwaseun O. Babatunde, Madeleine G. Bibby, Anthony Atala, Graça Almeida‐Porada, Christopher D. Porada   +4 more
wiley   +1 more source

National Multi-Sectoral Strategic Framework on HIV/AIDS 2003 - 2007 [PDF]

, 2003
Tanzania is facing a major threat to the survival of its people and the development chances of the nation from a concentrated and generalised HIV /AIDS epidemic. More than two Million people are estimated to be living with HIV /AIDS in 2002.
Tanzania Commission for HIV/AIDS, (TCAIDS)
core  

Disease Progression Mathematical Modeling With a Case Study on Hepatitis B Virus Infection

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 420-434, March 2025.
ABSTRACT Chronic Hepatitis B presents a significant health and socioeconomic burden. The risk of hepatocellular carcinoma remains elevated although treatments are available. Achieving an optimal treatment regimen necessitates a deep comprehension of the dynamic relationship between the virus and its host across disease states.
Clémence Boivin‐Champeaux, Nieves Velez de Mendizabal, Aksana Jones, Scott Balsitis, Stephan Schmidt, Justin S. Feigelman, Francine Johansson Azeredo   +6 more
wiley   +1 more source