Results 111 to 120 of about 66,330 (250)
HIV-1 Transcription and Latency in the Spotlight
VirusesAt every integrated HIV-1 genome, there is a transcriptional cycle that ultimately shapes proviral fate [...]
openaire +3 more sources
PLoS Pathogens, 2019 The establishment of HIV-1 latency gives rise to persistent chronic infection that requires life-long treatment. To reverse latency for viral eradiation, the HIV-1 Tat protein and its associated ELL2-containing Super Elongation Complexes (ELL2-SECs) are ...
Zichong Li +6 more
doaj +1 more source
Nonthermal plasma approaches for combating implant‐associated infections: A compendious review
VIEW, EarlyView.Implant‐associated infections pose serious clinical challenges. Non‐thermal plasma (NTP) modifications overcome this bottleneck in distinct ways relative to traditional sterilization methods. Gas‐phase plasmas generate highly energetic species, UV radiation and reactive oxygen/nitrogen species (RONS), which alter the implant surface properties.
A. M. Trimukhe +8 more
wiley +1 more source
Gender &History, EarlyView.ABSTRACT A new archive of oral history interviews from LGBTQIA‐identified alumni, faculty and staff reveals the complex ways that queer and transgender students understood, experienced and remembered the long transition from single‐sex to coeducation at Princeton University.
Ezelle Sanford III +2 more
wiley +1 more source
CBP/p300 lysine acetyltransferases inhibit HIV-1 expression in latently infected T cells
iScienceSummary: HIV-1 latency is regulated by chromatin modifying enzymes, and histone deacetylase inhibitors (HDACi) cause reactivation of provirus expression.
Riley M. Horvath, Ivan Sadowski
doaj +1 more source
Chronic Pruritic Papular Eruption in an Elderly Man
JEADV Clinical Practice, EarlyView.
Filipe Monteiro +6 more
wiley +1 more source
The Paediatric BCG Vaccine Century: From Historical Success to Future Innovations
Acta Paediatrica, EarlyView.ABSTRACT Aim The tuberculosis (TB) vaccine, Bacille‐Calmette‐Guérin (BCG), protects infants against severe forms of primary TB. Yet, it does not protect against pulmonary reactivation TB in adults. Methods A literature review was conducted between 1st January and 28th February 2025 using PubMed, Google Scholar and reports of the World Health ...
Stefan H. E. Kaufmann
wiley +1 more source
Scientific Reports, 2017 A potential strategy to cure HIV-1 infection is to use latency reversing agents (LRAs) to eliminate latent reservoirs established in resting CD4+ T (rCD4+) cells.
María Rosa López-Huertas +7 more
doaj +1 more source
Business Ethics, the Environment &Responsibility, EarlyView.ABSTRACT This paper examines the current state of the art regarding the contribution of Higher Education Institutions (HEIs) to the achievement of the Sustainable Development Goals (SDGs). We conducted a Systematic Literature Review Analysis (SLRA), which integrates a traditional Systematic Literature Review (SLR) with Bibliographic Analysis (BA), on a
Pasquale Latella, Stefania Veltri
wiley +1 more source
Epigenetic Regulation of HIV-1 Latency by Cytosine Methylation
PLoS Pathogens, 2009 Human immunodeficiency virus type 1 (HIV-1) persists in a latent state within resting CD4+ T cells of infected persons treated with highly active antiretroviral therapy (HAART). This reservoir must be eliminated for the clearance of infection. Using a cDNA library screen, we have identified methyl-CpG binding domain protein 2 (MBD2) as a regulator of ...
Kauder, Steven E +4 more
openaire +6 more sources