Editorial: The relevance of molecular mechanisms in HIV-1 latency and reactivation from latency
Alexander O. Pasternak +4 more
doaj +1 more source
Clustered mutations in HIV-1 gag are consistently required for escape from HLA-B27-restricted cytotoxic T lymphocyte responses [PDF]
The immune response to HIV-1 in patients who carry human histocompatibility leukocyte antigen (HLA)-B27 is characterized by an immunodominant response to an epitope in p24 gag (amino acids 263-272, KR WIILGLNK).
Anthony D. Kelleher +38 more
core +1 more source
Evaluating the neutralizing antibody response to HIV-1 membrane proximal external regional; Implications for vaccine design [PDF]
Includes bibliographical references.Inducing broadly neutralizing antibodies targeting the HIV-1 envelope is thought to be crucial for developing an effective vaccine.
Jacob, Rajesh Abraham
core +1 more source
Alexander O. Pasternak +4 more
doaj +1 more source
Promoter Methylation of HIV Coreceptor-Related Genes CCR5 and CXCR4: Original Research
The persistence of human immunodeficiency virus (HIV) within viral reservoirs poses significant challenges to eradication efforts. Epigenetic alterations, including DNA methylation, are potential factors influencing the latency and persistence of HIV ...
Anna Esman +8 more
doaj +1 more source
Concurrent sexual partnerships and HIV prevalence in five urban communities of sub-Saharan Africa. [PDF]
OBJECTIVE: To estimate parameters of concurrent sexual partnerships in five urban populations in sub-Saharan Africa and to assess their association with levels of HIV infection and other sexually transmitted infections (STI).
Lagarde, E. +24 more
core +1 more source
Anaemia in acute HIV-1 subtype C infection. [PDF]
BACKGROUND: The high prevalence of anaemia and the increased morbidity and mortality associated with anaemia during AIDS has been well described yet there has been little information about anaemia and changes in haemoglobin levels during acute and early ...
Auld, Sara C +43 more
core +2 more sources
HIV persistence in the setting of antiretroviral therapy: when, where and how does HIV hide?
Advances in the treatment of HIV infection have dramatically reduced the death rate from AIDS and improved the quality of life of many HIV-infected individuals. However, the possible long-term toxicity associated with antiretroviral therapy (ART), stigma
Deanna A. Kulpa, Nicolas Chomont
doaj +1 more source
Cost-effectiveness of voluntary HIV-1 counseling and testing in reducing sexual transmission of HIV-1 in Kenya and Tanzania. [PDF]
Background Access to HIV-1 voluntary counseling and testing (VCT) is severely limited in less-developed countries. We undertook a multisite trial of HIV-1 VCT to assess its impact, cost, and cost-effectiveness in less-developed country settings.\ud ...
Sangiwa , G +7 more
core
Where in the Cell Are You? Probing HIV-1 Host Interactions through Advanced Imaging Techniques
Viruses must continuously evolve to hijack the host cell machinery in order to successfully replicate and orchestrate key interactions that support their persistence. The type-1 human immunodeficiency virus (HIV-1) is a prime example of viral persistence
Brennan S. Dirk +2 more
doaj +1 more source

