Results 11 to 20 of about 83,958 (230)
Effective use of mesenchymal stem cells in human skin substitutes generated by tissue engineering [PDF]
Mesenchymal stem cells (MSCs) can differentiate toward epithelial cells and may be used as an alternative source for generation of heterotypical artificial human skin substitutes, thus, enhancing their development and translation potential to the clinic.
MA Martin-Piedra +8 more
doaj +1 more source
Opsonic and protective properties of antibodies raised to conjugate vaccines targeting six Staphylococcus aureus antigens. [PDF]
Staphylococcus aureus is a major cause of nosocomial and community-acquired infections for which a vaccine is greatly desired. Antigens found on the S. aureus outer surface include the capsular polysaccharides (CP) of serotype 5 (CP5) or 8 (CP8) and/or a
Clarissa Pozzi +5 more
doaj +1 more source
Transplant rejection is the critical clinical end-point limiting indefinite survival after histocompatibility antigen (HLA) mismatched organ transplantation. The predominant cause of late graft loss is antibody-mediated rejection (AMR), a process whereby
Silvia Pineda +7 more
doaj +1 more source
Binding of TCR multimers and a TCR-like antibody with distinct fine-specificities is dependent on the surface density of HLA complexes. [PDF]
Class I Major Histocompatibility Complex (MHC) molecules evolved to sample degraded protein fragments from the interior of the cell, and to display them at the surface for immune surveillance by CD8(+) T cells.
Jianrong L Low +9 more
doaj +1 more source
Type 1 Diabetes and Autoimmune Thyroid Disease—The Genetic Link
Type 1 diabetes (T1D) and autoimmune thyroid disease (AITD) are the most frequent chronic autoimmune diseases worldwide. Several autoimmune endocrine and non-endocrine disorders tend to occur together.
Lara Frommer, George J. Kahaly
doaj +1 more source
Subpopulation composition of peripheral blood lymphocytes in COVID-19
The pathogenesis of severe coronavirus infection COVID-19 is associated with activation of immune system, cytokine storm, impaired blood clotting, microvascular thrombosis, organ ischemia and multiple organ dysfunction syndrome.
E. V. Svirshchevskaya +4 more
doaj +1 more source
Three HLA-D region antigens defined by primed LD typing. [PDF]
We have recently described a new method, primed LD typing or PLT, for specific identification of HLA-D antigens. Highly discriminatory PLT cells have been developed which clearly differentiate between cells of individuals that restimulate strongly and those that restimulate weakly.
F H, Bach +5 more
openaire +2 more sources
Donor-recipient (D-R) mismatches outside of human leukocyte antigens (HLAs) contribute to kidney allograft loss, but the mechanisms remain unclear, specifically for intronic mismatches. We quantified non-HLA mismatches at variant-, gene-, and genome-wide
Zeguo Sun +17 more
doaj +1 more source
HLA-D Region Antigen Expression by Human Epidermal Langerhans Cells
We have systematically examined HLA-D region antigen expression by normal human epidermal Langerhans cells with an improved double label indirect immunofluorescence technique in order to better understand the immunologic potential of this human interstitial dendritic cell type.
Sontheimer, Richard D +2 more
openaire +2 more sources
Risk of Transfusion Complication: A Systematic Review of Iranian Literature [PDF]
Background and aims: Injecting healthy blood on time can save patients’ lives; on the other hand, delaying the start of transfusion or injecting unhealthy and wrong blood can cause fatal risks.
Hamidreza Azizi Farsani +6 more
doaj +1 more source

