Results 41 to 50 of about 795,110 (304)

Sex-Specific Differences in HLA Antibodies after Pneumococcal Vaccination in Kidney Transplant Recipients

Vaccines, 2019
In transplant recipients vaccination against Streptococcus pneumoniae is recommended to reduce mortality from invasive pneumococcal disease. It is still debated if vaccination in transplant recipients triggers alloresponses.
Monika Lindemann, Simon Oesterreich, Benjamin Wilde, Ute Eisenberger, Nils Muelling, Peter A. Horn, Falko M. Heinemann, Oliver Witzke   +7 more
doaj   +1 more source

Fc galactosylation of anti-platelet human IgG1 alloantibodies enhances complement activation on platelets

Haematologica, 2022
Approximately 20% of patients receiving multiple platelet transfusions develop platelet alloantibodies, which can be directed against human leukocyte antigens (HLA) and, to a lesser extent, against human platelet antigens (HPA).
Thijs L.J. van Osch, Janita J. Oosterhoff, Arthur E. H. Bentlage, Jan Nouta, Carolien A. M. Koeleman, Dionne M. Geerdes, Juk Yee Mok, Sebastiaan Heidt, Arend Mulder, Wim J. E. van Esch, Rick Kapur, Leendert Porcelijn, C. Ellen van der Schoot, Masja de Haas, Manfred Wuhrer, Jan Voorberg, Gestur Vidarsson   +16 more
doaj   +1 more source

Significance of HLA-matching and anti-HLA antibodies in heart transplant patients receiving induction therapy?

, 2022
OBJECTIVES: Though Human Leukocyte Antigen (HLA) matching benefits are demonstrated in renal transplantation, evidence in heart transplantation is lacking, and its clinical feasibility is uncertain.
Poncelet, Alain, Van Caenegem, Olivier, Latinne, Dominique, Gavroy, Benjamin, Timmermans, Thierry, Jacquet, Luc-Marie, Mastrobuoni, Stefano   +6 more
core   +1 more source

Anti-HLA and Anti-MICA Antibodies in Liver Transplant Recipients: Effect on Long-Term Graft Survival

Clinical and Developmental Immunology, 2013
Objective. Presence of anti-HLA antibodies has a well-known impact on kidney grafts survival; however their role in liver transplantation has not been fully elucidated.
Michał Ciszek, Bartosz Foroncewicz, Krzysztof Mucha, Dorota Żochowska, Bogna Ziarkiewicz-Wróblewska, Marek Krawczyk, Leszek Pączek   +6 more
doaj   +1 more source

Study on transfusion-related acute lung injury caused by HLA-Ⅱ antibody

Zhongguo shuxue zazhi, 2023
Objective To explore the risk factors of transfusion-related acute lung injury (TRALI). Methods The clinical symptoms, signs, imaging examinations, and laboratory test results of two patients with TRALI after blood transfusion were retrospectively ...
Yu ZOU, Mao ZHENG, Xin JI, Xiuyun LIAO, Tianhua JIANG, Jue WANG   +5 more
doaj   +1 more source

Frequency of HLA antibodies in South India [PDF]

, 1993
Sera from 4088 pregnant women (649 antenatal bleeding and 3439 post-partum bleeding) living in Madurai, were collected and screened for anti-HLA. A, B and DR antibodies. 696 of them were screened for anti-HLA DR antibodies.
Mahendran, V., Manuel, May, Balakrishnan, K., Shankar Kumar, U., Indra Raja, V., Brahmajothi, V., Pitchappan, R. M., Amutha, S., Shantha Kumari, R., Sashidhar, M., SamalRaj   +10 more
core   +1 more source

Elimination of HLA antibodies by platelet adsorption [PDF]

Immunohematology, 2020
Abstract The presence of HLA antibodies in patient serum or plasma may make antibody identification difficult. These HLA antibodies may mask the presence of clinically significant red blood cell (RBC) alloantibodies. Because platelets strongly express HLA antigens, it is possible to remove HLA antibodies by adsorbing the patient’s ...
Jung, J., Barron, C.
openaire   +2 more sources

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit, Chiranth K. Nagaraj, Jackson S. Newell, Kim Truc Nguyen, Xilal Y. Rima, Jacob Doon‐Ralls, Eduardo Reátegui, Jeffrey M. Statland, Rabi Tawil, Kevin M. Flanigan, Scott Q. Harper, Nizar Y. Saad   +11 more
wiley   +1 more source

Association between Anti-Ganglionic Nicotinic Acetylcholine Receptor (gAChR) Antibodies and HLA-DRB1 Alleles in the Japanese Population.

PLoS ONE, 2016
Background/aimsAnti-ganglionic nicotinic acetylcholine receptor (gAChR) antibodies are observed in autoimmune diseases, as well as in patients with autoimmune autonomic ganglionopathy.
Yasuhiro Maeda, Kiyoshi Migita, Osamu Higuchi, Akihiro Mukaino, Hiroshi Furukawa, Atsumasa Komori, Minoru Nakamura, Satoru Hashimoto, Shinya Nagaoka, Seigo Abiru, Hiroshi Yatsuhashi, Hidenori Matsuo, Atsushi Kawakami, Michio Yasunami, Shunya Nakane   +14 more
doaj   +1 more source