Results 61 to 70 of about 795,110 (304)
Acta Scientiarum. Health Sciences, 2015 While a 42-year-old male patient was being prepared for deceased-donor renal transplantation, anti-HLA-A2 antibodies were detected in the serum by enzyme-linked immunosorbent assay (ELISA) method.
Hugo Mendonça Mundim +5 more
doaj +1 more source
Frontiers in Immunology, 2022 To examine the production time, type, and MFI of post-transplantation de novo HLA antibodies, and their effects on haplo-HSCT outcomes, we retrospectively included 116 patients who were negative for pre-existing HLA antibodies.
Lan Wang +13 more
doaj +1 more source
E5 protein of human papillomavirus type 16 selectively downregulates surface HLA class I [PDF]
, 2005 Papillomaviruses have evolved mechanisms that result in escape from host immune surveillance. The E5 protein is expressed early in papillomavirus infection in the deep layers of the infected epithelium.
Marchetti, Barbara +9 more
core +1 more source
Advanced Science, EarlyView.Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang +6 more
wiley +1 more source
Antibody verification of HLA class I and class II eplets by human monoclonal HLA antibodies [PDF]
In solid organ transplantation, formation of de novo donor-specific HLA antibodies is induced by mismatched eplets on donor HLA molecules. While several studies have shown a strong correlation between the number of eplet mismatches and inferior outcomes,
Franke-van Dijk, M.E.I. +7 more
core +3 more sources
Validation of Anti-HLA Antibodies in Serum of Blood Transfused or Organ Transplanted Patients
Eurasian Journal of Medicine, 2019 Objective: The role of HLA molecules in innate immunity is well known. It has also been established that anti-HLA antibodies are produced by blood transfusion, multiparous women, previous transplantation, and autoimmune diseases.
Gönül Zişan Öncel +3 more
doaj
Вестник трансплантологии и искусственных органов, 2016 Aim: to analyze the relationship between circulating anti-HLA antibodies (class-I and class-II), renal pathology and C4d deposition in cases of late acute and chronic antibody-mediated renal allograft rejection according to the method of antibodies ...
E. S. Ivanova +6 more
doaj +1 more source
Advanced Science, EarlyView.4D bioprinted hydrogel loaded with FGF2‐modified extracellular vesicles (4D@F‐EVs) targets dermal fibroblasts and elevates local wound FGF2 levels via sustained release of F‐EVs. It activates PI3K‐Akt signaling, restores critical KGF+ fibroblast–KGFR+ keratinocyte crosstalk, enhances robust angiogenesis and collagen deposition to efficiently repair ...
Xiaomin Wang +19 more
wiley +1 more source
Advanced Science, EarlyView.A biomimetic doppelgänger nanosystem neutralizes extracellular inflammatory cytokines and silences intracellular pyroptosis, reprogramming pathogenic macrophages to attenuate both joint and spine degeneration. ABSTRACT Osteoarthritis (OA) and intervertebral disc degeneration (IVDD) are debilitating musculoskeletal disorders driven by shared ...
Fudong Li +9 more
wiley +1 more source
Overcoming Drug Resistance by Paclitaxel Resistance in Triple‐Negative Breast Cancer
Advanced Science, EarlyView.In the murine triple‐negative breast cancer (TNBC) model, chemotherapy effectively increases tumor neoantigen burden (TNB). Here, the study constructs a liposomal nanovaccine using antigens derived from in vitro chemotherapy‐treated paclitaxel‐resistant TNBC 4T1 cells.
Bo Chen +10 more
wiley +1 more source