Results 11 to 20 of about 25,975 (254)

Evaluation of HLA typing content of next-generation sequencing datasets from family trios and individuals of arab ethnicity [PDF]

Frontiers in Genetics
Introduction: HLA typing is a critical tool in both clinical and research applications at the individual and population levels. Benchmarking studies have indicated HLA-HD as the preferred tool for accurate and comprehensive HLA allele calling. The advent
Mohammed Dashti, Md Zubbair Malik, Rasheeba Nizam, Sindhu Jacob, Fahd Al-Mulla, Thangavel Alphonse Thanaraj   +5 more
doaj   +2 more sources

Personalized HLA typing leads to the discovery of novel HLA alleles and tumor‐specific HLA variants [PDF]

Hla, 2022
Trevor Clancy
exaly   +2 more sources

The Impact of COVID-19 on Healthy Related Issues, A structured Review

مجله كليه طب الكندي, 2021
Coronavirus: (COVID-19) is a recently discovered viral disease caused by a new strain of coronavirus. The majority of patients with corona-virus infections will have a mild-moderate respiratory disease that recovers without special care.
Hiyam Rauof Al-Hamamy
doaj   +1 more source

High-Resolution HLA Typing of HLA-A, -B, -C, -DRB1, and -DQB1 in Kinh Vietnamese by Using Next-Generation Sequencing [PDF]

Frontiers in Genetics, 2020
Tran Ngoc Dang, Minh Duc, Dang Tran Ngoc   +2 more
exaly   +2 more sources

High resolution HLA-DRB1 analysis and shared molecular amino acid signature of DRβ1 molecules in Occult hepatitis B infection

BMC Immunology, 2022
Aim To investigate the association of human leukocyte antigen (HLA)-DRB1 alleles and the variations of polymorphic amino acid changes in DRβ1 chain in Shaanxi Han population with Occult hepatitis B infection (OBI).
Tianju Wang, Chunmei Shen, Hengxin Li, Liping Chen, Sheng Liu, Jun Qi   +5 more
doaj   +1 more source

Development of a high-resolution mass-spectrometry-based method and software for human leukocyte antigen typing

Frontiers in Immunology, 2023
IntroductionThe human leukocyte antigen (HLA) system plays a critical role in the human immune system and is strongly associated with immune recognition and rejection in organ transplantation.
Kun Wang, Zetao Sun, Fei Zhu, Yunping Xu, Feng Zhou   +4 more
doaj   +1 more source

Diagnosis of COVID-19: facts and challenges

New Microbes and New Infections, 2020
At the end of 2019, the novel coronavirus disease 2019 (COVID-19) emerged in Wuhan, China, then spread rapidly across the country and throughout the world.
H.H. Zalzala
doaj   +1 more source

HLA typing from 1000 genomes whole genome and whole exome illumina data. [PDF]

PLoS ONE, 2013
Specific HLA genotypes are known to be linked to either resistance or susceptibility to certain diseases or sensitivity to certain drugs. In addition, high accuracy HLA typing is crucial for organ and bone marrow transplantation. The most widespread high
Endre Major, Krisztina Rigó, Tim Hague, Attila Bérces, Szilveszter Juhos   +4 more
doaj   +1 more source

SOAPTyping: an open-source and cross-platform tool for sequence-based typing for HLA class I and II alleles

BMC Bioinformatics, 2020
Background The human leukocyte antigen (HLA) gene family plays a key role in the immune response and thus is crucial in many biomedical and clinical settings.
Yong Zhang, Yongsheng Chen, Huixin Xu, Junbin Fang, Zijian Zhao, Weipeng Hu, Xiaoqin Yang, Jia Ye, Yun Cheng, Jiayin Wang, Weiqiang Sun, Jian Wang, Huanming Yang, Jing Yan, Lin Fang   +14 more
doaj   +1 more source

Measuring ambiguity in HLA typing methods. [PDF]

PLoS ONE, 2012
In hematopoietic stem cell transplantation, donor selection is based primarily on matching donor and patient HLA genes. These genes are highly polymorphic and their typing can result in exact allele assignment at each gene (the resolution at which ...
Vanja Paunić, Loren Gragert, Abeer Madbouly, John Freeman, Martin Maiers   +4 more
doaj   +1 more source