Results 61 to 70 of about 2,248 (159)

Glucose 6‐phosphate dehydrogenase variants increase NADPH pools for yeast isoprenoid production

FEBS Open Bio, Volume 14, Issue 3, Page 410-425, March 2024.
This study focuses on enhancing isoprenoid yields by increasing NADPH levels. Gene fusions of S. cerevisiae glucose 6‐phosphate dehydrogenase (ScG6PD) with 6‐phosphogluconolactonase (6PGL) and truncated HMG‐CoA reductase were created, and overexpressing them yielded higher sclareol (diterpenoid). Rational mutagenesis of ScG6PD identified mutants (N403D
Sri Harsha Adusumilli, Anuthariq Alikkam Veetil, Chinmayee Choudhury, Banani Chattopadhyaya, Diptimayee Behera, Anand Kumar Bachhawat   +5 more
wiley   +1 more source

Rat liver HMG1: a physiological nucleosome assembly factor. [PDF]

The EMBO Journal, 1984
Incubation of rat liver single-stranded DNA-binding protein HMG1 with the four core histones at 0.15 M NaCl favors histone association primarily into tetramers and, to a lesser extent, into octamers. The assembly of pre-formed histone-HMG1 complexes with DNA yields nucleosome-like subunits which satisfy most of the criteria defining native core ...
C, Bonne-Andrea, F, Harper, J, Sobczak, A M, De Recondo   +3 more
openaire   +2 more sources

Human umbilical cord mesenchymal stem cell‐derived exosomes attenuate neuroinflammation and oxidative stress through the NRF2/NF‐κB/NLRP3 pathway

CNS Neuroscience &Therapeutics, Volume 30, Issue 3, March 2024.
Human umbilical cord mesenchymal stem cell (hUC‐MSC)‐derived exosomes reduce neuroinflammation and oxidative stress in in vitro and in vivo models. Abstract Aims We investigated whether human umbilical cord mesenchymal stem cell (hUC‐MSC)‐derived exosomes bear therapeutic potential against lipopolysaccharide (LPS)‐induced neuroinflammation.
Ji Che, Hui Wang, Jing Dong, Yuanyuan Wu, Haichao Zhang, Lei Fu, Jun Zhang   +6 more
wiley   +1 more source

Priming avocado with sodium hydrosulfide prior to frost conditions induces the expression of genes involved in protection and stress responses

Physiologia Plantarum, Volume 176, Issue 2, March/April 2024.
Abstract Priming plants with chemical agents has been extensively investigated as a means for improving their tolerance to many biotic and abiotic stresses. Earlier, we showed that priming young avocado (Persea americana Mill cv. ‘Hass’) trees with sodium hydrosulfide (NaHS), a donor of hydrogen sulfide, improves the response of photosynthesis to ...
Vivekanand Tiwari, Yuval Bussi, Itzhak Kamara, Adi Faigenboim, Vered Irihimovitch, Dana Charuvi   +5 more
wiley   +1 more source

Boosting the biosynthesis of betulinic acid and related triterpenoids in Yarrowia lipolytica via multimodular metabolic engineering

Microbial Cell Factories, 2019
Background Betulinic acid is a pentacyclic lupane-type triterpenoid and a potential antiviral and antitumor drug, but the amount of betulinic acid in plants is low and cannot meet the demand for this compound. Yarrowia lipolytica, as an oleaginous yeast,
Cong-Cong Jin, Jin-Lai Zhang, Hao Song, Ying-Xiu Cao   +3 more
doaj   +1 more source

Improving High Light Tolerance of Tobacco Plants: Adequate Magnesium Supply Enhances Photosynthetic Performance

Agronomy
High light (HL) significantly impacts plant photosynthesis. This study investigated the effects of different magnesium (Mg) levels (0, 1, 2, and 5 mol Mg plant−1; HMg0, HMg1, HMg2, and HMg5) on tobacco (Nicotiana tabacum L. cv. Cuibi No.
Rongrong Xie, Jingjuan Gao, Zongfeng Yang, Yuemin Wang, Liangyuan Tong, Yuqin Ke, Chunjian Li, Chaoyuan Zheng, Wenqing Li   +8 more
doaj   +1 more source

Genomic landscape of Candidozyma auris in Italy, 2019 to 2025: emerging diversity of clade I sub-lineages associated with inter-facility transmission and cross-border transfers

Eurosurveillance
BACKGROUND Candidozyma auris is a fungal pathogen of major concern, that frequently exhibits multidrug resistance and causes healthcare-related outbreaks worldwide.
Anna Marchese
doaj   +1 more source

Mutational analysis of the DNA binding domain A of chromosomal protein HMG1

Nucleic Acids Research, 1994
We have mutated several residues of the first of the two HMG-boxes of mammalian HMG1. Some mutants cannot be produced in Escherichia coli, suggesting that the peptide fold is grossly disrupted. A few others can be produced efficiently and have normal DNA binding affinity and specificity; however, they are more sensitive towards heating and chaotropic ...
Falciola, L, Murchie, A I, Lilley, D M, Bianchi, M   +3 more
openaire   +4 more sources

Ashbya gossypii as a versatile platform to produce sabinene from agro-industrial wastes

Fungal Biology and Biotechnology
Background Ashbya gossypii is a filamentous fungus widely utilized for industrial riboflavin production and has a great potential as a microbial chassis for synthesizing other valuable metabolites such as folates, biolipids, and limonene.
Gloria Muñoz-Fernández, Javier-Fernando Montero-Bullón, José Luis Martínez, Rubén M. Buey, Alberto Jiménez   +4 more
doaj   +1 more source

Nucleotide sequence of rat liver HMG1 cDNA

Nucleic Acids Research, 1987
G, Paonessa, R, Frank, R, Cortese
openaire   +3 more sources