Results 61 to 70 of about 2,854 (146)

Engineering of Yarrowia lipolytica for production of astaxanthin

Synthetic and Systems Biotechnology, 2017
Astaxanthin is a red-colored carotenoid, used as food and feed additive. Astaxanthin is mainly produced by chemical synthesis, however, the process is expensive and synthetic astaxanthin is not approved for human consumption. In this study, we engineered
Kanchana Rueksomtawin Kildegaard, Belén Adiego-Pérez, David Doménech Belda, Jaspreet Kaur Khangura, Carina Holkenbrink, Irina Borodina   +5 more
doaj   +1 more source

New developments in biotechnology applied to microorganisms

EFSA Journal, Volume 22, Issue 7, July 2024.
Abstract EFSA was requested by the European Commission (in accordance with Article 29 of Regulation (EC) No 178/2002) to provide a scientific opinion on the application of new developments in biotechnology (new genomic techniques, NGTs) to viable microorganisms and products of category 4 to be released into the environment or placed on the market as or
EFSA Panel on Genetically Modified Organisms (GMO), Ewen Mullins, Jean‐Louis Bresson, Ian Crawford Dewhurst, Michelle M. Epstein, Leslie George Firbank, Philippe Guerche, Jan Hejatko, Francisco Javier Moreno, Hanspeter Naegeli, Fabien Nogué, Nils Rostoks, Jose Juan Sánchez Serrano, Giovanni Savoini, Eve Veromann, Fabio Veronesi, Pier Sandro Cocconcelli, Debora Glandorf, Lieve Herman, Rodrigo Jimenez Saiz, Lorena Ruiz Garcia, Jaime Aguilera Entrena, Andrea Gennaro, Reinhilde Schoonjans, Dafni Maria Kagkli, Tamas Dalmay   +25 more
wiley   +1 more source

Glucose 6‐phosphate dehydrogenase variants increase NADPH pools for yeast isoprenoid production

FEBS Open Bio, Volume 14, Issue 3, Page 410-425, March 2024.
This study focuses on enhancing isoprenoid yields by increasing NADPH levels. Gene fusions of S. cerevisiae glucose 6‐phosphate dehydrogenase (ScG6PD) with 6‐phosphogluconolactonase (6PGL) and truncated HMG‐CoA reductase were created, and overexpressing them yielded higher sclareol (diterpenoid). Rational mutagenesis of ScG6PD identified mutants (N403D
Sri Harsha Adusumilli, Anuthariq Alikkam Veetil, Chinmayee Choudhury, Banani Chattopadhyaya, Diptimayee Behera, Anand Kumar Bachhawat   +5 more
wiley   +1 more source

Effects of Fatty Acids from Coconut and Olive Oil on Expression of the HMG1 Gene and Feeding Behavior in Tetrahymena thermophila [PDF]

, 2019
HMG-CoA reductase is an enzyme involved in the biosynthetic pathways of sterols in many different organisms. The gene in Tetrahymena thermophila which codes for this protein is HMG1, and has many homologs across many other organisms, from fungi to humans.
Konen, Amelia, Stewart, Taryn
core   +2 more sources

Human umbilical cord mesenchymal stem cell‐derived exosomes attenuate neuroinflammation and oxidative stress through the NRF2/NF‐κB/NLRP3 pathway

CNS Neuroscience &Therapeutics, Volume 30, Issue 3, March 2024.
Human umbilical cord mesenchymal stem cell (hUC‐MSC)‐derived exosomes reduce neuroinflammation and oxidative stress in in vitro and in vivo models. Abstract Aims We investigated whether human umbilical cord mesenchymal stem cell (hUC‐MSC)‐derived exosomes bear therapeutic potential against lipopolysaccharide (LPS)‐induced neuroinflammation.
Ji Che, Hui Wang, Jing Dong, Yuanyuan Wu, Haichao Zhang, Lei Fu, Jun Zhang   +6 more
wiley   +1 more source

Interaction of linker proteins, H1 and HMG1, with nucleosome reconstituted on positioning sequences [PDF]

The aim of this research was to gain more understanding on how a linker histone (LH), H1⁰, and high mobility group protein, HMG1, interact with nucleosome.
An, Woojin
core   +6 more sources

Priming avocado with sodium hydrosulfide prior to frost conditions induces the expression of genes involved in protection and stress responses

Physiologia Plantarum, Volume 176, Issue 2, March/April 2024.
Abstract Priming plants with chemical agents has been extensively investigated as a means for improving their tolerance to many biotic and abiotic stresses. Earlier, we showed that priming young avocado (Persea americana Mill cv. ‘Hass’) trees with sodium hydrosulfide (NaHS), a donor of hydrogen sulfide, improves the response of photosynthesis to ...
Vivekanand Tiwari, Yuval Bussi, Itzhak Kamara, Adi Faigenboim, Vered Irihimovitch, Dana Charuvi   +5 more
wiley   +1 more source

INTERACTION OF DOXORUBICIN WITH DNA-HMG1 COMPLEX [PDF]

Journal of Sciences, Islamic Republic of Iran, 1995
In this study, the interaction of the anthracycline antibiotic doxorubicin with DNA-HMG 1 complex was investigated employing UV/VIS spectroscopy, thermal denaturation and DNA cellulose chromatography techniques.
doaj  

The lack of chromosomal protein Hmg1 does not disrupt cell growth but causes lethal hypoglycaemia in newborn mice.

, 1999
High mobility group 1 (HMG1) protein is an abundant component of all mammalian nuclei, and related proteins exist in all eukaryotes. HMG1 binds linear DNA with moderate affinity and no sequence specificity, but bends the double helix significantly on ...
Grassi, F, A. Aguzzi, Calogero, S, S. Calogero, ME Bianchi, T. Voigtländer, Aguzzi, A; https://orcid.org/, Voigtländer, T, Ferrier, P, Bianchi, M E, Ferrari, S, P. Ferrier, F Grassi, S. Ferrari   +13 more
core   +1 more source

Secretion and binding of HMG1 protein to the external surface of the membrane are required for murine erythroleukemia cell differentiation [PDF]

, 1997
We show here that murine erythroleukemia (MEL) cells, following induction with hexamethylene bisacetamide, accumulate high mobility group (HMG)1 protein onto the external surface of the cell in a membrane-associated form detectable by immunostaining with
Mauro Patrone, Sandro Pontremoli, Pontremoli, Sandro, Antonio Zicca, Passalacqua, Mario, Sparatore, Bianca, Patrone, Mauro, Edon Melloni, Bianca Sparatore, Zicca, Antonio, Melloni, Edon, Mario Passalacqua   +11 more
core   +1 more source